7V0Y

Local refinement of Band 3-III cytoplasmic domains, class 1 of erythrocyte ankyrin-1 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0005452	molecular_function	solute:inorganic anion antiporter activity
C	0005515	molecular_function	protein binding
C	0005737	cellular_component	cytoplasm
C	0005886	cellular_component	plasma membrane
C	0006811	biological_process	monoatomic ion transport
C	0006820	biological_process	monoatomic anion transport
C	0006821	biological_process	chloride transport
C	0006873	biological_process	intracellular monoatomic ion homeostasis
C	0007596	biological_process	blood coagulation
C	0008092	molecular_function	cytoskeletal protein binding
C	0008509	molecular_function	monoatomic anion transmembrane transporter activity
C	0009898	cellular_component	cytoplasmic side of plasma membrane
C	0015106	molecular_function	bicarbonate transmembrane transporter activity
C	0015108	molecular_function	chloride transmembrane transporter activity
C	0015297	molecular_function	antiporter activity
C	0015701	biological_process	bicarbonate transport
C	0016020	cellular_component	membrane
C	0016323	cellular_component	basolateral plasma membrane
C	0017121	biological_process	plasma membrane phospholipid scrambling
C	0030018	cellular_component	Z disc
C	0030492	molecular_function	hemoglobin binding
C	0030506	molecular_function	ankyrin binding
C	0030863	cellular_component	cortical cytoskeleton
C	0035811	biological_process	negative regulation of urine volume
C	0036296	biological_process	response to increased oxygen levels
C	0042803	molecular_function	protein homodimerization activity
C	0043495	molecular_function	protein-membrane adaptor activity
C	0045852	biological_process	pH elevation
C	0048821	biological_process	erythrocyte development
C	0051453	biological_process	regulation of intracellular pH
C	0055085	biological_process	transmembrane transport
C	0070062	cellular_component	extracellular exosome
C	0072562	cellular_component	blood microparticle
C	0072659	biological_process	protein localization to plasma membrane
C	0140900	molecular_function	chloride:bicarbonate antiporter activity
C	0170014	cellular_component	ankyrin-1 complex
C	1902476	biological_process	chloride transmembrane transport
C	1904539	biological_process	negative regulation of glycolytic process through fructose-6-phosphate
E	0005452	molecular_function	solute:inorganic anion antiporter activity
E	0005515	molecular_function	protein binding
E	0005737	cellular_component	cytoplasm
E	0005886	cellular_component	plasma membrane
E	0006811	biological_process	monoatomic ion transport
E	0006820	biological_process	monoatomic anion transport
E	0006821	biological_process	chloride transport
E	0006873	biological_process	intracellular monoatomic ion homeostasis
E	0007596	biological_process	blood coagulation
E	0008092	molecular_function	cytoskeletal protein binding
E	0008509	molecular_function	monoatomic anion transmembrane transporter activity
E	0009898	cellular_component	cytoplasmic side of plasma membrane
E	0015106	molecular_function	bicarbonate transmembrane transporter activity
E	0015108	molecular_function	chloride transmembrane transporter activity
E	0015297	molecular_function	antiporter activity
E	0015701	biological_process	bicarbonate transport
E	0016020	cellular_component	membrane
E	0016323	cellular_component	basolateral plasma membrane
E	0017121	biological_process	plasma membrane phospholipid scrambling
E	0030018	cellular_component	Z disc
E	0030492	molecular_function	hemoglobin binding
E	0030506	molecular_function	ankyrin binding
E	0030863	cellular_component	cortical cytoskeleton
E	0035811	biological_process	negative regulation of urine volume
E	0036296	biological_process	response to increased oxygen levels
E	0042803	molecular_function	protein homodimerization activity
E	0043495	molecular_function	protein-membrane adaptor activity
E	0045852	biological_process	pH elevation
E	0048821	biological_process	erythrocyte development
E	0051453	biological_process	regulation of intracellular pH
E	0055085	biological_process	transmembrane transport
E	0070062	cellular_component	extracellular exosome
E	0072562	cellular_component	blood microparticle
E	0072659	biological_process	protein localization to plasma membrane
E	0140900	molecular_function	chloride:bicarbonate antiporter activity
E	0170014	cellular_component	ankyrin-1 complex
E	1902476	biological_process	chloride transmembrane transport
E	1904539	biological_process	negative regulation of glycolytic process through fructose-6-phosphate

Functional Information from PROSITE/UniProt

site_id	PS00219
Number of Residues	12
Details	ANION_EXCHANGER_1 Anion exchangers family signature 1. FGGLVRDIRRRY

Chain	Residue	Details
E	PHE379-TYR390

---

site_id	PS00220
Number of Residues	15
Details	ANION_EXCHANGER_2 Anion exchangers family signature 2. FLISLIFIYETFsKL

Chain	Residue	Details
E	PHE526-LEU540

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	9
Details	Region: {"description":"Interaction with ANK1","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P23562","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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