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7V0U

Local refinement of Band 3-II cytoplasmic domains, class 1 of erythrocyte ankyrin-1 complex

Functional Information from GO Data
ChainGOidnamespacecontents
D0005452molecular_functionsolute:inorganic anion antiporter activity
D0005515molecular_functionprotein binding
D0005737cellular_componentcytoplasm
D0005886cellular_componentplasma membrane
D0006811biological_processmonoatomic ion transport
D0006820biological_processmonoatomic anion transport
D0006821biological_processchloride transport
D0006873biological_processintracellular monoatomic ion homeostasis
D0007596biological_processblood coagulation
D0008092molecular_functioncytoskeletal protein binding
D0008509molecular_functionmonoatomic anion transmembrane transporter activity
D0009898cellular_componentcytoplasmic side of plasma membrane
D0015106molecular_functionbicarbonate transmembrane transporter activity
D0015108molecular_functionchloride transmembrane transporter activity
D0015297molecular_functionantiporter activity
D0015701biological_processbicarbonate transport
D0016020cellular_componentmembrane
D0016323cellular_componentbasolateral plasma membrane
D0017121biological_processplasma membrane phospholipid scrambling
D0030018cellular_componentZ disc
D0030492molecular_functionhemoglobin binding
D0030506molecular_functionankyrin binding
D0030863cellular_componentcortical cytoskeleton
D0035811biological_processnegative regulation of urine volume
D0036296biological_processresponse to increased oxygen levels
D0042803molecular_functionprotein homodimerization activity
D0043495molecular_functionprotein-membrane adaptor activity
D0045852biological_processpH elevation
D0048821biological_processerythrocyte development
D0051453biological_processregulation of intracellular pH
D0055085biological_processtransmembrane transport
D0070062cellular_componentextracellular exosome
D0072562cellular_componentblood microparticle
D0072659biological_processprotein localization to plasma membrane
D0140900molecular_functionchloride:bicarbonate antiporter activity
D0170014cellular_componentankyrin-1 complex
D1902476biological_processchloride transmembrane transport
D1904539biological_processnegative regulation of glycolytic process through fructose-6-phosphate
F0005452molecular_functionsolute:inorganic anion antiporter activity
F0005515molecular_functionprotein binding
F0005737cellular_componentcytoplasm
F0005886cellular_componentplasma membrane
F0006811biological_processmonoatomic ion transport
F0006820biological_processmonoatomic anion transport
F0006821biological_processchloride transport
F0006873biological_processintracellular monoatomic ion homeostasis
F0007596biological_processblood coagulation
F0008092molecular_functioncytoskeletal protein binding
F0008509molecular_functionmonoatomic anion transmembrane transporter activity
F0009898cellular_componentcytoplasmic side of plasma membrane
F0015106molecular_functionbicarbonate transmembrane transporter activity
F0015108molecular_functionchloride transmembrane transporter activity
F0015297molecular_functionantiporter activity
F0015701biological_processbicarbonate transport
F0016020cellular_componentmembrane
F0016323cellular_componentbasolateral plasma membrane
F0017121biological_processplasma membrane phospholipid scrambling
F0030018cellular_componentZ disc
F0030492molecular_functionhemoglobin binding
F0030506molecular_functionankyrin binding
F0030863cellular_componentcortical cytoskeleton
F0035811biological_processnegative regulation of urine volume
F0036296biological_processresponse to increased oxygen levels
F0042803molecular_functionprotein homodimerization activity
F0043495molecular_functionprotein-membrane adaptor activity
F0045852biological_processpH elevation
F0048821biological_processerythrocyte development
F0051453biological_processregulation of intracellular pH
F0055085biological_processtransmembrane transport
F0070062cellular_componentextracellular exosome
F0072562cellular_componentblood microparticle
F0072659biological_processprotein localization to plasma membrane
F0140900molecular_functionchloride:bicarbonate antiporter activity
F0170014cellular_componentankyrin-1 complex
F1902476biological_processchloride transmembrane transport
F1904539biological_processnegative regulation of glycolytic process through fructose-6-phosphate
Functional Information from PROSITE/UniProt
site_idPS00219
Number of Residues12
DetailsANION_EXCHANGER_1 Anion exchangers family signature 1. FGGLVRDIRRRY
ChainResidueDetails
FPHE379-TYR390

site_idPS00220
Number of Residues15
DetailsANION_EXCHANGER_2 Anion exchangers family signature 2. FLISLIFIYETFsKL
ChainResidueDetails
FPHE526-LEU540

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues9
DetailsRegion: {"description":"Interaction with ANK1","evidences":[{"evidenceCode":"ECO:0000305"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues1
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P23562","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

243083

PDB entries from 2025-10-15

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