7U5V
Crystal structure of the Mixed Lineage Leukaemia (MLL1) SET Domain with the cofactor product S-Adenosylhomocysteine and Borealin peptide
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 116 |
| Details | Domain: {"description":"SET","evidences":[{"source":"PROSITE-ProRule","id":"PRU00190","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00190","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"19187761","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26886794","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2W5Y","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5F5E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5F6L","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00190","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"19187761","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26886794","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2W5Z","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5F5E","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"19187761","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26886794","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2W5Y","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5F5E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5F6L","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16990798","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19187761","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2W5Y","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2W5Z","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5F5E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5F6L","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"S-methylcysteine; by autocatalysis","evidences":[{"source":"PubMed","id":"24235145","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
