7T0R
Crystal structure of the anti-CD4 adnectin 6940_B01 as a complex with the extracellular domains of CD4 and ibalizumab fAb
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006955 | biological_process | immune response |
| A | 0007155 | biological_process | cell adhesion |
| A | 0015026 | molecular_function | coreceptor activity |
| A | 0016020 | cellular_component | membrane |
| D | 0006955 | biological_process | immune response |
| D | 0007155 | biological_process | cell adhesion |
| D | 0015026 | molecular_function | coreceptor activity |
| D | 0016020 | cellular_component | membrane |
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH |
| Chain | Residue | Details |
| L | TYR197-HIS203 | |
| H | TYR203-HIS209 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 198 |
| Details | Domain: {"description":"Ig-like V-type"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 226 |
| Details | Domain: {"description":"Ig-like C2-type 2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 112 |
| Details | Domain: {"description":"Ig-like C2-type 3"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","featureId":"CAR_000053","evidences":[{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"2001369","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"2592374","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","featureId":"CAR_000054","evidences":[{"source":"PubMed","id":"2001369","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"2592374","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
