7T0O
cryoEM reconstruction of the HIV gp140 in complex with the extracellular domains of CD4 and the adnectin domain of Combinectin. The gp140 and CD4 coordinates from entry 6EDU were rigid body fitted to the EM map along withe the crystal structure of CD4+adnectin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| D | 0005198 | molecular_function | structural molecule activity |
| D | 0019031 | cellular_component | viral envelope |
| G | 0005198 | molecular_function | structural molecule activity |
| G | 0019031 | cellular_component | viral envelope |
| H | 0006955 | biological_process | immune response |
| H | 0007155 | biological_process | cell adhesion |
| H | 0015026 | molecular_function | coreceptor activity |
| H | 0016020 | cellular_component | membrane |
| I | 0005198 | molecular_function | structural molecule activity |
| I | 0019031 | cellular_component | viral envelope |
| L | 0006955 | biological_process | immune response |
| L | 0007155 | biological_process | cell adhesion |
| L | 0015026 | molecular_function | coreceptor activity |
| L | 0016020 | cellular_component | membrane |
| M | 0006955 | biological_process | immune response |
| M | 0007155 | biological_process | cell adhesion |
| M | 0015026 | molecular_function | coreceptor activity |
| M | 0016020 | cellular_component | membrane |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI12 |
| Number of Residues | 198 |
| Details | Domain: {"description":"Ig-like V-type"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI13 |
| Number of Residues | 339 |
| Details | Domain: {"description":"Ig-like C2-type 2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI14 |
| Number of Residues | 168 |
| Details | Domain: {"description":"Ig-like C2-type 3"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI15 |
| Number of Residues | 3 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","featureId":"CAR_000053","evidences":[{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"2001369","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"2592374","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI16 |
| Number of Residues | 3 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","featureId":"CAR_000054","evidences":[{"source":"PubMed","id":"2001369","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"2592374","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
