7RPK

Cryo-EM structure of murine Dispatched in complex with Sonic hedgehog

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016020	cellular_component	membrane
H	0007267	biological_process	cell-cell signaling
H	0007275	biological_process	multicellular organism development

Functional Information from PROSITE/UniProt

site_id	PS00284
Number of Residues	11
Details	SERPIN Serpins signature. LEFQSTFLFtL

Chain	Residue	Details
A	LEU923-LEU933

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	7
Details	BINDING: BINDING => ECO:0000269|PubMed:18794898, ECO:0000269|PubMed:19561611, ECO:0000269|PubMed:20519495

Chain	Residue	Details
H	GLU90
A	VAL1038-TYR1058
A	ILE1081-LEU1101
A	PHE1109-CYS1129
H	GLU91
H	ASP96
H	THR126
H	GLU127
H	ASP130
H	ASP132
A	MET986-ILE1006
A	LEU1008-LEU1028

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site_id	SWS_FT_FI2
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:18794898, ECO:0000269|PubMed:19561611, ECO:0000269|PubMed:20519495, ECO:0000269|PubMed:7477329

Chain	Residue	Details
H	HIS141
H	ASP148
H	HIS183

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