7QPB
Catalytic C-lobe of the HECT-type ubiquitin ligase E6AP in complex with a hybrid foldamer-peptide macrocycle
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000209 | biological_process | protein polyubiquitination |
| A | 0004842 | molecular_function | ubiquitin-protein transferase activity |
| A | 0061630 | molecular_function | ubiquitin protein ligase activity |
| B | 0000209 | biological_process | protein polyubiquitination |
| B | 0004842 | molecular_function | ubiquitin-protein transferase activity |
| B | 0061630 | molecular_function | ubiquitin protein ligase activity |
| C | 0000209 | biological_process | protein polyubiquitination |
| C | 0004842 | molecular_function | ubiquitin-protein transferase activity |
| C | 0061630 | molecular_function | ubiquitin protein ligase activity |
| D | 0000209 | biological_process | protein polyubiquitination |
| D | 0004842 | molecular_function | ubiquitin-protein transferase activity |
| D | 0061630 | molecular_function | ubiquitin protein ligase activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Glycyl thioester intermediate |
| Chain | Residue | Details |
| A | ILE843 | |
| B | ILE843 | |
| C | ILE843 | |
| D | ILE843 |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 2 |
| Details | M-CSA 438 |
| Chain | Residue | Details |
| A | HIS818 | |
| A | CYS820 | covalent catalysis |
| site_id | MCSA2 |
| Number of Residues | 2 |
| Details | M-CSA 438 |
| Chain | Residue | Details |
| B | HIS818 | |
| B | CYS820 | covalent catalysis |
| site_id | MCSA3 |
| Number of Residues | 2 |
| Details | M-CSA 438 |
| Chain | Residue | Details |
| C | HIS818 | |
| C | CYS820 | covalent catalysis |
| site_id | MCSA4 |
| Number of Residues | 2 |
| Details | M-CSA 438 |
| Chain | Residue | Details |
| D | HIS818 | |
| D | CYS820 | covalent catalysis |
