7Q5W
The tandem SH2 domains of SYK with a bound TYROBP diphospho-ITAM peptide
This is a non-PDB format compatible entry.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| AAA | 0004715 | molecular_function | non-membrane spanning protein tyrosine kinase activity |
| BBB | 0004715 | molecular_function | non-membrane spanning protein tyrosine kinase activity |
| CCC | 0004715 | molecular_function | non-membrane spanning protein tyrosine kinase activity |
| DDD | 0004715 | molecular_function | non-membrane spanning protein tyrosine kinase activity |
| EEE | 0004715 | molecular_function | non-membrane spanning protein tyrosine kinase activity |
| FFF | 0004715 | molecular_function | non-membrane spanning protein tyrosine kinase activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | MOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:O54885 |
| Chain | Residue | Details |
| GGG | PTR91 | |
| KKK | PTR102 | |
| LLL | PTR91 | |
| LLL | PTR102 | |
| GGG | PTR102 | |
| HHH | PTR91 | |
| HHH | PTR102 | |
| III | PTR91 | |
| III | PTR102 | |
| JJJ | PTR91 | |
| JJJ | PTR102 | |
| KKK | PTR91 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | MOD_RES: Phosphoserine => ECO:0000269|PubMed:21469132 |
| Chain | Residue | Details |
| AAA | SER44 | |
| EEE | SER202 | |
| FFF | SER44 | |
| FFF | SER202 | |
| AAA | SER202 | |
| BBB | SER44 | |
| BBB | SER202 | |
| CCC | SER44 | |
| CCC | SER202 | |
| DDD | SER44 | |
| DDD | SER202 | |
| EEE | SER44 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | MOD_RES: Phosphotyrosine => ECO:0000269|PubMed:21469132 |
| Chain | Residue | Details |
| AAA | TYR47 | |
| EEE | TYR131 | |
| FFF | TYR47 | |
| FFF | TYR131 | |
| AAA | TYR131 | |
| BBB | TYR47 | |
| BBB | TYR131 | |
| CCC | TYR47 | |
| CCC | TYR131 | |
| DDD | TYR47 | |
| DDD | TYR131 | |
| EEE | TYR47 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | MOD_RES: Phosphothreonine => ECO:0000269|PubMed:21469132 |
| Chain | Residue | Details |
| AAA | THR256 | |
| BBB | THR256 | |
| CCC | THR256 | |
| DDD | THR256 | |
| EEE | THR256 | |
| FFF | THR256 |
