7OUB
High resolution structure of Alpha-1-acid glycoprotein bound to potent anti-tumour compound UCN-01
Functional Information from GO Data
Chain | GOid | namespace | contents |
B | 0002682 | biological_process | regulation of immune system process |
B | 0005515 | molecular_function | protein binding |
B | 0005576 | cellular_component | extracellular region |
B | 0005615 | cellular_component | extracellular space |
B | 0006953 | biological_process | acute-phase response |
B | 0031093 | cellular_component | platelet alpha granule lumen |
B | 0032731 | biological_process | positive regulation of interleukin-1 beta production |
B | 0032732 | biological_process | positive regulation of interleukin-1 production |
B | 0032760 | biological_process | positive regulation of tumor necrosis factor production |
B | 0035578 | cellular_component | azurophil granule lumen |
B | 0035580 | cellular_component | specific granule lumen |
B | 0062023 | cellular_component | collagen-containing extracellular matrix |
B | 0070062 | cellular_component | extracellular exosome |
B | 0072562 | cellular_component | blood microparticle |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | MOD_RES: Pyrrolidone carboxylic acid => ECO:0000269|PubMed:15253437 |
Chain | Residue | Details |
B | GLN1 |
site_id | SWS_FT_FI2 |
Number of Residues | 1 |
Details | CARBOHYD: N-linked (GlcNAc...) (complex) asparagine => ECO:0000269|PubMed:14760718, ECO:0000269|PubMed:15084671, ECO:0000269|PubMed:15253437, ECO:0000269|PubMed:1567356, ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:19838169, ECO:0000269|PubMed:22171320 |
Chain | Residue | Details |
B | ASN15 |
site_id | SWS_FT_FI3 |
Number of Residues | 1 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:14760718, ECO:0000269|PubMed:1567356, ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19159218 |
Chain | Residue | Details |
B | ASN38 |
site_id | SWS_FT_FI4 |
Number of Residues | 1 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:14760718, ECO:0000269|PubMed:1567356, ECO:0000269|PubMed:16335952 |
Chain | Residue | Details |
B | ASN54 |
site_id | SWS_FT_FI5 |
Number of Residues | 1 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:14760718, ECO:0000269|PubMed:15253437, ECO:0000269|PubMed:1567356, ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19159218 |
Chain | Residue | Details |
B | ASN75 |
site_id | SWS_FT_FI6 |
Number of Residues | 1 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:1567356, ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19159218 |
Chain | Residue | Details |
B | ASN85 |