7OIX

Structure of thermostable human MFSD2A in complex with thermostable human Sync2

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0003406	biological_process	retinal pigment epithelium development
B	0005324	molecular_function	long-chain fatty acid transmembrane transporter activity
B	0005548	molecular_function	phospholipid transporter activity
B	0005764	cellular_component	lysosome
B	0005789	cellular_component	endoplasmic reticulum membrane
B	0005886	cellular_component	plasma membrane
B	0006656	biological_process	phosphatidylcholine biosynthetic process
B	0006869	biological_process	lipid transport
B	0007420	biological_process	brain development
B	0008594	biological_process	photoreceptor cell morphogenesis
B	0008643	biological_process	carbohydrate transport
B	0009267	biological_process	cellular response to starvation
B	0010867	biological_process	positive regulation of triglyceride biosynthetic process
B	0015245	molecular_function	fatty acid transmembrane transporter activity
B	0015293	molecular_function	symporter activity
B	0015908	biological_process	fatty acid transport
B	0015909	biological_process	long-chain fatty acid transport
B	0016020	cellular_component	membrane
B	0021766	biological_process	hippocampus development
B	0030307	biological_process	positive regulation of cell growth
B	0031999	biological_process	negative regulation of fatty acid beta-oxidation
B	0034204	biological_process	lipid translocation
B	0034379	biological_process	very-low-density lipoprotein particle assembly
B	0035633	biological_process	maintenance of blood-brain barrier
B	0035845	biological_process	photoreceptor cell outer segment organization
B	0040014	biological_process	regulation of multicellular organism growth
B	0045056	biological_process	transcytosis
B	0050773	biological_process	regulation of dendrite development
B	0050890	biological_process	cognition
B	0051977	biological_process	lysophospholipid transport
B	0051978	molecular_function	lysophospholipid:sodium symporter activity
B	0055085	biological_process	transmembrane transport
B	0060042	biological_process	retina morphogenesis in camera-type eye
B	0060856	biological_process	establishment of blood-brain barrier
B	0061744	biological_process	motor behavior
B	0097009	biological_process	energy homeostasis
B	0140329	biological_process	lysophospholipid translocation
B	0140348	molecular_function	lysophosphatidylcholine flippase activity
B	0150011	biological_process	regulation of neuron projection arborization
B	0150104	biological_process	transport across blood-brain barrier
B	0150172	biological_process	regulation of phosphatidylcholine metabolic process
B	0150175	biological_process	regulation of phosphatidylethanolamine metabolic process
B	1901480	molecular_function	oleate transmembrane transporter activity
B	1990379	biological_process	lipid transport across blood-brain barrier
B	1990403	biological_process	embryonic brain development
B	1990963	biological_process	establishment of blood-retinal barrier

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	7
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	244
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"UniProtKB","id":"Q9DA75","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	59
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"UniProtKB","id":"Q9DA75","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	32
Details	Topological domain: {"description":"Extracellular","evidences":[{"source":"UniProtKB","id":"Q9DA75","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"21677192","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---