7NZE
Crystal structure of HLA-DR4 in complex with a human collagen type II peptide
This is a non-PDB format compatible entry.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| AAA | 0006955 | biological_process | immune response |
| AAA | 0016020 | cellular_component | membrane |
| AAA | 0019882 | biological_process | antigen processing and presentation |
| AAA | 0042613 | cellular_component | MHC class II protein complex |
| BBB | 0006955 | biological_process | immune response |
| BBB | 0016020 | cellular_component | membrane |
| BBB | 0019882 | biological_process | antigen processing and presentation |
| BBB | 0042613 | cellular_component | MHC class II protein complex |
| CCC | 0006955 | biological_process | immune response |
| CCC | 0016020 | cellular_component | membrane |
| CCC | 0019882 | biological_process | antigen processing and presentation |
| CCC | 0042613 | cellular_component | MHC class II protein complex |
| DDD | 0006955 | biological_process | immune response |
| DDD | 0016020 | cellular_component | membrane |
| DDD | 0019882 | biological_process | antigen processing and presentation |
| DDD | 0042613 | cellular_component | MHC class II protein complex |
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCQVEH |
| Chain | Residue | Details |
| BBB | TYR171-HIS177 | |
| AAA | TYR161-HIS167 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | SITE: Self- and pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:21115828, ECO:0000269|PubMed:23260142, ECO:0000269|PubMed:8145819, ECO:0007744|PDB:4GBX |
| Chain | Residue | Details |
| AAA | GLN9 | |
| CCC | GLN9 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | SITE: Self-peptide antigen => ECO:0000269|PubMed:31619516 |
| Chain | Residue | Details |
| AAA | GLY49 | |
| AAA | ALA52 | |
| CCC | GLY49 | |
| CCC | ALA52 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | SITE: Self- and pathogen-derived peptide antigen => ECO:0000269|PubMed:21115828, ECO:0000269|PubMed:8145819 |
| Chain | Residue | Details |
| AAA | PHE51 | |
| CCC | PHE51 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | SITE: Self- and pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:21115828, ECO:0000269|PubMed:31619516, ECO:0000269|PubMed:8145819 |
| Chain | Residue | Details |
| AAA | SER53 | |
| CCC | SER53 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | SITE: Pathogen-derived peptide antigen => ECO:0000269|PubMed:23260142, ECO:0007744|PDB:4GBX |
| Chain | Residue | Details |
| AAA | GLU55 | |
| CCC | GLU55 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | SITE: Self- and pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:21115828, ECO:0000269|PubMed:23260142, ECO:0000269|PubMed:31619516, ECO:0000269|PubMed:8145819, ECO:0007744|PDB:4GBX |
| Chain | Residue | Details |
| AAA | ASN62 | |
| CCC | ASN62 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | SITE: Pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:21115828, ECO:0000269|PubMed:23260142, ECO:0000269|PubMed:8145819, ECO:0007744|PDB:4FQX, ECO:0007744|PDB:4GBX |
| Chain | Residue | Details |
| AAA | ASN69 | |
| CCC | ASN69 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | SITE: Self- and pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:23260142, ECO:0000269|PubMed:31619516, ECO:0000269|PubMed:8145819, ECO:0007744|PDB:4FQX, ECO:0007744|PDB:4GBX |
| Chain | Residue | Details |
| AAA | ARG76 | |
| CCC | ARG76 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 4 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:7477400 |
| Chain | Residue | Details |
| AAA | ASN78 | |
| AAA | ASN118 | |
| CCC | ASN78 | |
| CCC | ASN118 |
