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7NE1

Structure of the complex between Netrin-1 and its receptor Neogenin

Functional Information from GO Data
ChainGOidnamespacecontents
B0005887cellular_componentintegral component of plasma membrane
B0007399biological_processnervous system development
B0007411biological_processaxon guidance
B0030513biological_processpositive regulation of BMP signaling pathway
B0038023molecular_functionsignaling receptor activity
B0055072biological_processiron ion homeostasis
Functional Information from PROSITE/UniProt
site_idPS00022
Number of Residues12
DetailsEGF_1 EGF-like domain signature 1. CdCrhNtaGPeC
ChainResidueDetails
ACYS304-CYS315
ACYS423-CYS434

site_idPS01248
Number of Residues35
DetailsEGF_LAM_1 Laminin-type EGF-like (LE) domain signature. Cd.CrhntaGpeCdrCkpfhYdrpwqratareane.C
ChainResidueDetails
ACYS304-CYS338
ACYS368-CYS404
ACYS423-CYS451

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
AASN95
AASN116
AASN131
AASN417

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PDB entries from 2024-07-17

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