Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7LVB

CHOLERA TOXIN B SUBUNIT WITH ATTACHED SIV EPITOPE

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005534	molecular_function	galactose binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0020002	cellular_component	host cell plasma membrane
A	0035821	biological_process	modulation of process of another organism
A	0042531	biological_process	positive regulation of tyrosine phosphorylation of STAT protein
A	0042597	cellular_component	periplasmic space
A	0046812	molecular_function	host cell surface binding
A	0090729	molecular_function	toxin activity
A	1902494	cellular_component	catalytic complex
B	0005515	molecular_function	protein binding
B	0005534	molecular_function	galactose binding
B	0005576	cellular_component	extracellular region
B	0005615	cellular_component	extracellular space
B	0020002	cellular_component	host cell plasma membrane
B	0035821	biological_process	modulation of process of another organism
B	0042531	biological_process	positive regulation of tyrosine phosphorylation of STAT protein
B	0042597	cellular_component	periplasmic space
B	0046812	molecular_function	host cell surface binding
B	0090729	molecular_function	toxin activity
B	1902494	cellular_component	catalytic complex
C	0005515	molecular_function	protein binding
C	0005534	molecular_function	galactose binding
C	0005576	cellular_component	extracellular region
C	0005615	cellular_component	extracellular space
C	0020002	cellular_component	host cell plasma membrane
C	0035821	biological_process	modulation of process of another organism
C	0042531	biological_process	positive regulation of tyrosine phosphorylation of STAT protein
C	0042597	cellular_component	periplasmic space
C	0046812	molecular_function	host cell surface binding
C	0090729	molecular_function	toxin activity
C	1902494	cellular_component	catalytic complex
D	0005515	molecular_function	protein binding
D	0005534	molecular_function	galactose binding
D	0005576	cellular_component	extracellular region
D	0005615	cellular_component	extracellular space
D	0020002	cellular_component	host cell plasma membrane
D	0035821	biological_process	modulation of process of another organism
D	0042531	biological_process	positive regulation of tyrosine phosphorylation of STAT protein
D	0042597	cellular_component	periplasmic space
D	0046812	molecular_function	host cell surface binding
D	0090729	molecular_function	toxin activity
D	1902494	cellular_component	catalytic complex
E	0005515	molecular_function	protein binding
E	0005534	molecular_function	galactose binding
E	0005576	cellular_component	extracellular region
E	0005615	cellular_component	extracellular space
E	0020002	cellular_component	host cell plasma membrane
E	0035821	biological_process	modulation of process of another organism
E	0042531	biological_process	positive regulation of tyrosine phosphorylation of STAT protein
E	0042597	cellular_component	periplasmic space
E	0046812	molecular_function	host cell surface binding
E	0090729	molecular_function	toxin activity
E	1902494	cellular_component	catalytic complex
F	0005515	molecular_function	protein binding
F	0005534	molecular_function	galactose binding
F	0005576	cellular_component	extracellular region
F	0005615	cellular_component	extracellular space
F	0020002	cellular_component	host cell plasma membrane
F	0035821	biological_process	modulation of process of another organism
F	0042531	biological_process	positive regulation of tyrosine phosphorylation of STAT protein
F	0042597	cellular_component	periplasmic space
F	0046812	molecular_function	host cell surface binding
F	0090729	molecular_function	toxin activity
F	1902494	cellular_component	catalytic complex
G	0005515	molecular_function	protein binding
G	0005534	molecular_function	galactose binding
G	0005576	cellular_component	extracellular region
G	0005615	cellular_component	extracellular space
G	0020002	cellular_component	host cell plasma membrane
G	0035821	biological_process	modulation of process of another organism
G	0042531	biological_process	positive regulation of tyrosine phosphorylation of STAT protein
G	0042597	cellular_component	periplasmic space
G	0046812	molecular_function	host cell surface binding
G	0090729	molecular_function	toxin activity
G	1902494	cellular_component	catalytic complex
H	0005515	molecular_function	protein binding
H	0005534	molecular_function	galactose binding
H	0005576	cellular_component	extracellular region
H	0005615	cellular_component	extracellular space
H	0020002	cellular_component	host cell plasma membrane
H	0035821	biological_process	modulation of process of another organism
H	0042531	biological_process	positive regulation of tyrosine phosphorylation of STAT protein
H	0042597	cellular_component	periplasmic space
H	0046812	molecular_function	host cell surface binding
H	0090729	molecular_function	toxin activity
H	1902494	cellular_component	catalytic complex
I	0005515	molecular_function	protein binding
I	0005534	molecular_function	galactose binding
I	0005576	cellular_component	extracellular region
I	0005615	cellular_component	extracellular space
I	0020002	cellular_component	host cell plasma membrane
I	0035821	biological_process	modulation of process of another organism
I	0042531	biological_process	positive regulation of tyrosine phosphorylation of STAT protein
I	0042597	cellular_component	periplasmic space
I	0046812	molecular_function	host cell surface binding
I	0090729	molecular_function	toxin activity
I	1902494	cellular_component	catalytic complex
J	0005515	molecular_function	protein binding
J	0005534	molecular_function	galactose binding
J	0005576	cellular_component	extracellular region
J	0005615	cellular_component	extracellular space
J	0020002	cellular_component	host cell plasma membrane
J	0035821	biological_process	modulation of process of another organism
J	0042531	biological_process	positive regulation of tyrosine phosphorylation of STAT protein
J	0042597	cellular_component	periplasmic space
J	0046812	molecular_function	host cell surface binding
J	0090729	molecular_function	toxin activity
J	1902494	cellular_component	catalytic complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	binding site for residue GAL D 201

Chain	Residue
D	GLU51
D	GLN56
D	HIS57
D	GLN61
D	TRP88
D	ASN90
D	LYS91
D	HOH336
D	HOH339

site_id	AC2
Number of Residues	2
Details	binding site for residue PGE D 202

Chain	Residue
D	GLU11
D	CL204

site_id	AC3
Number of Residues	3
Details	binding site for residue PGE D 203

Chain	Residue
D	ARG35
H	GLU11
H	CL202

site_id	AC4
Number of Residues	2
Details	binding site for residue CL D 204

Chain	Residue
D	HIS13
D	PGE202

site_id	AC5
Number of Residues	9
Details	binding site for residue GAL E 201

Chain	Residue
E	GLU51
E	GLN56
E	HIS57
E	GLN61
E	TRP88
E	ASN90
E	LYS91
E	HOH348
F	HOH324

site_id	AC6
Number of Residues	2
Details	binding site for residue PGE E 202

Chain	Residue
E	TYR12
F	ARG35

site_id	AC7
Number of Residues	1
Details	binding site for residue CL E 203

Chain	Residue
E	HIS13

site_id	AC8
Number of Residues	9
Details	binding site for residue GAL F 201

Chain	Residue
F	GLU51
F	GLN56
F	GLN61
F	TRP88
F	ASN90
F	LYS91
F	HOH311
F	HOH323
F	HOH336

site_id	AC9
Number of Residues	2
Details	binding site for residue PGE F 202

Chain	Residue
F	GLU11
F	HOH353

site_id	AD1
Number of Residues	4
Details	binding site for residue PGE F 203

Chain	Residue
E	THR78
F	TYR76
F	LEU77
F	HOH358

site_id	AD2
Number of Residues	10
Details	binding site for residue GAL G 201

Chain	Residue
G	GLU51
G	GLN56
G	HIS57
G	GLN61
G	TRP88
G	ASN90
G	LYS91
G	HOH311
G	HOH322
G	HOH327

site_id	AD3
Number of Residues	3
Details	binding site for residue PGE G 202

Chain	Residue
G	GLU11
G	CL203
H	ARG35

site_id	AD4
Number of Residues	2
Details	binding site for residue CL G 203

Chain	Residue
G	HIS13
G	PGE202

site_id	AD5
Number of Residues	2
Details	binding site for residue CL G 204

Chain	Residue
G	THR92
J	ASN44

site_id	AD6
Number of Residues	8
Details	binding site for residue GAL H 201

Chain	Residue
H	GLU51
H	GLN56
H	GLN61
H	TRP88
H	ASN90
H	LYS91
H	HOH310
H	HOH329

site_id	AD7
Number of Residues	2
Details	binding site for residue CL H 202

Chain	Residue
D	PGE203
H	HIS13

site_id	AD8
Number of Residues	9
Details	binding site for residue GAL A 201

Chain	Residue
A	GLU51
A	GLN56
A	HIS57
A	GLN61
A	TRP88
A	ASN90
A	LYS91
A	HOH329
A	HOH349

site_id	AD9
Number of Residues	4
Details	binding site for residue PGE A 202

Chain	Residue
A	GLU11
A	TYR12
A	CL204
B	ARG35

site_id	AE1
Number of Residues	5
Details	binding site for residue PGE A 203

Chain	Residue
A	THR78
A	GLU79
A	HOH318
B	TYR76
B	LEU77

site_id	AE2
Number of Residues	2
Details	binding site for residue CL A 204

Chain	Residue
A	HIS13
A	PGE202

site_id	AE3
Number of Residues	9
Details	binding site for residue GAL B 201

Chain	Residue
B	GLU51
B	GLN56
B	HIS57
B	GLN61
B	TRP88
B	ASN90
B	LYS91
B	HOH350
C	HOH333

site_id	AE4
Number of Residues	3
Details	binding site for residue PGE B 202

Chain	Residue
B	GLU11
B	TYR12
B	CL204

site_id	AE5
Number of Residues	3
Details	binding site for residue PGE B 203

Chain	Residue
B	PHE25
B	PHE42
B	GLY45

site_id	AE6
Number of Residues	2
Details	binding site for residue CL B 204

Chain	Residue
B	HIS13
B	PGE202

site_id	AE7
Number of Residues	2
Details	binding site for residue CL B 205

Chain	Residue
B	HIS18
B	THR19

site_id	AE8
Number of Residues	9
Details	binding site for residue GAL C 201

Chain	Residue
C	GLU51
C	GLN56
C	HIS57
C	GLN61
C	TRP88
C	ASN90
C	LYS91
C	HOH351
I	HOH338

site_id	AE9
Number of Residues	4
Details	binding site for residue PGE C 202

Chain	Residue
C	GLU11
C	TYR12
C	CL204
I	ARG35

site_id	AF1
Number of Residues	4
Details	binding site for residue PGE C 203

Chain	Residue
C	THR78
C	GLU79
C	HOH310
I	LEU77

site_id	AF2
Number of Residues	2
Details	binding site for residue CL C 204

Chain	Residue
C	HIS13
C	PGE202

site_id	AF3
Number of Residues	10
Details	binding site for residue GAL I 201

Chain	Residue
I	GLU51
I	GLN56
I	HIS57
I	GLN61
I	TRP88
I	ASN90
I	LYS91
I	HOH306
I	HOH326
J	HOH353

site_id	AF4
Number of Residues	2
Details	binding site for residue PGE I 202

Chain	Residue
I	CL204
J	ARG35

site_id	AF5
Number of Residues	2
Details	binding site for residue PGE I 203

Chain	Residue
I	PHE25
I	GLY45

site_id	AF6
Number of Residues	2
Details	binding site for residue CL I 204

Chain	Residue
I	HIS13
I	PGE202

site_id	AF7
Number of Residues	9
Details	binding site for residue GAL J 201

Chain	Residue
A	HOH321
J	GLU51
J	GLN56
J	HIS57
J	GLN61
J	TRP88
J	ASN90
J	LYS91
J	HOH310

site_id	AF8
Number of Residues	2
Details	binding site for residue PGE J 202

Chain	Residue
J	GLU11
J	CL203

site_id	AF9
Number of Residues	2
Details	binding site for residue CL J 203

Chain	Residue
J	HIS13
J	PGE202

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)