Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

7LR0

Structure of squirrel TRPV1 in complex with capsaicin

Functional Information from GO Data
ChainGOidnamespacecontents
A0000122biological_processnegative regulation of transcription by RNA polymerase II
A0001659biological_processtemperature homeostasis
A0001660biological_processfever generation
A0002024biological_processdiet induced thermogenesis
A0002790biological_processpeptide secretion
A0005216molecular_functionmonoatomic ion channel activity
A0005230molecular_functionextracellular ligand-gated monoatomic ion channel activity
A0005261molecular_functionmonoatomic cation channel activity
A0005262molecular_functioncalcium channel activity
A0005516molecular_functioncalmodulin binding
A0005524molecular_functionATP binding
A0005886cellular_componentplasma membrane
A0006629biological_processlipid metabolic process
A0006811biological_processmonoatomic ion transport
A0006816biological_processcalcium ion transport
A0009268biological_processresponse to pH
A0009408biological_processresponse to heat
A0014832biological_processurinary bladder smooth muscle contraction
A0016020cellular_componentmembrane
A0019233biological_processsensory perception of pain
A0032591cellular_componentdendritic spine membrane
A0034220biological_processmonoatomic ion transmembrane transport
A0034605biological_processcellular response to heat
A0043005cellular_componentneuron projection
A0045211cellular_componentpostsynaptic membrane
A0048265biological_processresponse to pain
A0048266biological_processbehavioral response to pain
A0050909biological_processsensory perception of taste
A0050954biological_processsensory perception of mechanical stimulus
A0050955biological_processthermoception
A0050960biological_processdetection of temperature stimulus involved in thermoception
A0050965biological_processdetection of temperature stimulus involved in sensory perception of pain
A0050968biological_processdetection of chemical stimulus involved in sensory perception of pain
A0051219molecular_functionphosphoprotein binding
A0055085biological_processtransmembrane transport
A0060083biological_processsmooth muscle contraction involved in micturition
A0070588biological_processcalcium ion transmembrane transport
A0071468biological_processcellular response to acidic pH
A0097603molecular_functiontemperature-gated ion channel activity
A0098703biological_processcalcium ion import across plasma membrane
A0098982cellular_componentGABA-ergic synapse
A1901594biological_processresponse to capsazepine
B0000122biological_processnegative regulation of transcription by RNA polymerase II
B0001659biological_processtemperature homeostasis
B0001660biological_processfever generation
B0002024biological_processdiet induced thermogenesis
B0002790biological_processpeptide secretion
B0005216molecular_functionmonoatomic ion channel activity
B0005230molecular_functionextracellular ligand-gated monoatomic ion channel activity
B0005261molecular_functionmonoatomic cation channel activity
B0005262molecular_functioncalcium channel activity
B0005516molecular_functioncalmodulin binding
B0005524molecular_functionATP binding
B0005886cellular_componentplasma membrane
B0006629biological_processlipid metabolic process
B0006811biological_processmonoatomic ion transport
B0006816biological_processcalcium ion transport
B0009268biological_processresponse to pH
B0009408biological_processresponse to heat
B0014832biological_processurinary bladder smooth muscle contraction
B0016020cellular_componentmembrane
B0019233biological_processsensory perception of pain
B0032591cellular_componentdendritic spine membrane
B0034220biological_processmonoatomic ion transmembrane transport
B0034605biological_processcellular response to heat
B0043005cellular_componentneuron projection
B0045211cellular_componentpostsynaptic membrane
B0048265biological_processresponse to pain
B0048266biological_processbehavioral response to pain
B0050909biological_processsensory perception of taste
B0050954biological_processsensory perception of mechanical stimulus
B0050955biological_processthermoception
B0050960biological_processdetection of temperature stimulus involved in thermoception
B0050965biological_processdetection of temperature stimulus involved in sensory perception of pain
B0050968biological_processdetection of chemical stimulus involved in sensory perception of pain
B0051219molecular_functionphosphoprotein binding
B0055085biological_processtransmembrane transport
B0060083biological_processsmooth muscle contraction involved in micturition
B0070588biological_processcalcium ion transmembrane transport
B0071468biological_processcellular response to acidic pH
B0097603molecular_functiontemperature-gated ion channel activity
B0098703biological_processcalcium ion import across plasma membrane
B0098982cellular_componentGABA-ergic synapse
B1901594biological_processresponse to capsazepine
C0000122biological_processnegative regulation of transcription by RNA polymerase II
C0001659biological_processtemperature homeostasis
C0001660biological_processfever generation
C0002024biological_processdiet induced thermogenesis
C0002790biological_processpeptide secretion
C0005216molecular_functionmonoatomic ion channel activity
C0005230molecular_functionextracellular ligand-gated monoatomic ion channel activity
C0005261molecular_functionmonoatomic cation channel activity
C0005262molecular_functioncalcium channel activity
C0005516molecular_functioncalmodulin binding
C0005524molecular_functionATP binding
C0005886cellular_componentplasma membrane
C0006629biological_processlipid metabolic process
C0006811biological_processmonoatomic ion transport
C0006816biological_processcalcium ion transport
C0009268biological_processresponse to pH
C0009408biological_processresponse to heat
C0014832biological_processurinary bladder smooth muscle contraction
C0016020cellular_componentmembrane
C0019233biological_processsensory perception of pain
C0032591cellular_componentdendritic spine membrane
C0034220biological_processmonoatomic ion transmembrane transport
C0034605biological_processcellular response to heat
C0043005cellular_componentneuron projection
C0045211cellular_componentpostsynaptic membrane
C0048265biological_processresponse to pain
C0048266biological_processbehavioral response to pain
C0050909biological_processsensory perception of taste
C0050954biological_processsensory perception of mechanical stimulus
C0050955biological_processthermoception
C0050960biological_processdetection of temperature stimulus involved in thermoception
C0050965biological_processdetection of temperature stimulus involved in sensory perception of pain
C0050968biological_processdetection of chemical stimulus involved in sensory perception of pain
C0051219molecular_functionphosphoprotein binding
C0055085biological_processtransmembrane transport
C0060083biological_processsmooth muscle contraction involved in micturition
C0070588biological_processcalcium ion transmembrane transport
C0071468biological_processcellular response to acidic pH
C0097603molecular_functiontemperature-gated ion channel activity
C0098703biological_processcalcium ion import across plasma membrane
C0098982cellular_componentGABA-ergic synapse
C1901594biological_processresponse to capsazepine
D0000122biological_processnegative regulation of transcription by RNA polymerase II
D0001659biological_processtemperature homeostasis
D0001660biological_processfever generation
D0002024biological_processdiet induced thermogenesis
D0002790biological_processpeptide secretion
D0005216molecular_functionmonoatomic ion channel activity
D0005230molecular_functionextracellular ligand-gated monoatomic ion channel activity
D0005261molecular_functionmonoatomic cation channel activity
D0005262molecular_functioncalcium channel activity
D0005516molecular_functioncalmodulin binding
D0005524molecular_functionATP binding
D0005886cellular_componentplasma membrane
D0006629biological_processlipid metabolic process
D0006811biological_processmonoatomic ion transport
D0006816biological_processcalcium ion transport
D0009268biological_processresponse to pH
D0009408biological_processresponse to heat
D0014832biological_processurinary bladder smooth muscle contraction
D0016020cellular_componentmembrane
D0019233biological_processsensory perception of pain
D0032591cellular_componentdendritic spine membrane
D0034220biological_processmonoatomic ion transmembrane transport
D0034605biological_processcellular response to heat
D0043005cellular_componentneuron projection
D0045211cellular_componentpostsynaptic membrane
D0048265biological_processresponse to pain
D0048266biological_processbehavioral response to pain
D0050909biological_processsensory perception of taste
D0050954biological_processsensory perception of mechanical stimulus
D0050955biological_processthermoception
D0050960biological_processdetection of temperature stimulus involved in thermoception
D0050965biological_processdetection of temperature stimulus involved in sensory perception of pain
D0050968biological_processdetection of chemical stimulus involved in sensory perception of pain
D0051219molecular_functionphosphoprotein binding
D0055085biological_processtransmembrane transport
D0060083biological_processsmooth muscle contraction involved in micturition
D0070588biological_processcalcium ion transmembrane transport
D0071468biological_processcellular response to acidic pH
D0097603molecular_functiontemperature-gated ion channel activity
D0098703biological_processcalcium ion import across plasma membrane
D0098982cellular_componentGABA-ergic synapse
D1901594biological_processresponse to capsazepine
Functional Information from PDB Data
site_idAC1
Number of Residues4
Detailsbinding site for residue POV A 901
ChainResidue
APOV902
A4DY903
APOV905
BPHE657

site_idAC2
Number of Residues3
Detailsbinding site for residue POV A 902
ChainResidue
ATYR633
APOV901
BLYS658

site_idAC3
Number of Residues9
Detailsbinding site for residue 4DY A 903
ChainResidue
APHE545
ATHR552
ATYR556
APOV901
BPHE593
BLEU664
BLEU671
ASER514
ALEU517

site_idAC4
Number of Residues7
Detailsbinding site for residue POV A 904
ChainResidue
AASN439
AVAL442
ATYR443
AARG493
AGLU515
APHE518
ATYR557

site_idAC5
Number of Residues5
Detailsbinding site for residue POV A 905
ChainResidue
AVAL510
AMET549
AILE575
ALEU576
APOV901

site_idAC6
Number of Residues6
Detailsbinding site for residue POV A 906
ChainResidue
AGLU480
AMET525
ASER528
ATYR532
APHE533
AMET543

site_idAC7
Number of Residues6
Detailsbinding site for residue POV A 907
ChainResidue
ATYR455
BMET583
BLEU587
BLEU590
BPHE591
BCYS636

site_idAC8
Number of Residues8
Detailsbinding site for residue POV A 908
ChainResidue
ATYR437
APHE440
APHE561
AGLN563
AMET564
BCYS580
BMET583
BPHE584

site_idAC9
Number of Residues4
Detailsbinding site for residue POV A 909
ChainResidue
APHE657
DPOV903
D4DY904
DPOV906

site_idAD1
Number of Residues4
Detailsbinding site for residue POV B 901
ChainResidue
BPOV902
B4DY903
BPOV905
CPHE657

site_idAD2
Number of Residues3
Detailsbinding site for residue POV B 902
ChainResidue
BTYR633
BPOV901
CLYS658

site_idAD3
Number of Residues9
Detailsbinding site for residue 4DY B 903
ChainResidue
BSER514
BLEU517
BPHE545
BTHR552
BTYR556
BPOV901
CPHE593
CLEU664
CLEU671

site_idAD4
Number of Residues7
Detailsbinding site for residue POV B 904
ChainResidue
BASN439
BVAL442
BTYR443
BARG493
BGLU515
BPHE518
BTYR557

site_idAD5
Number of Residues4
Detailsbinding site for residue POV B 905
ChainResidue
BMET549
BILE575
BLEU576
BPOV901

site_idAD6
Number of Residues6
Detailsbinding site for residue POV B 906
ChainResidue
BGLU480
BMET525
BSER528
BTYR532
BPHE533
BMET543

site_idAD7
Number of Residues6
Detailsbinding site for residue POV B 907
ChainResidue
BTYR455
CMET583
CLEU587
CLEU590
CPHE591
CCYS636

site_idAD8
Number of Residues8
Detailsbinding site for residue POV B 908
ChainResidue
BTYR437
BPHE440
BPHE561
BGLN563
BMET564
CCYS580
CMET583
CPHE584

site_idAD9
Number of Residues4
Detailsbinding site for residue POV C 901
ChainResidue
CPOV902
C4DY903
CPOV905
DPHE657

site_idAE1
Number of Residues3
Detailsbinding site for residue POV C 902
ChainResidue
CTYR633
CPOV901
DLYS658

site_idAE2
Number of Residues9
Detailsbinding site for residue 4DY C 903
ChainResidue
CSER514
CLEU517
CPHE545
CTHR552
CTYR556
CPOV901
DPHE593
DLEU664
DLEU671

site_idAE3
Number of Residues7
Detailsbinding site for residue POV C 904
ChainResidue
CASN439
CVAL442
CTYR443
CARG493
CGLU515
CPHE518
CTYR557

site_idAE4
Number of Residues4
Detailsbinding site for residue POV C 905
ChainResidue
CMET549
CILE575
CLEU576
CPOV901

site_idAE5
Number of Residues6
Detailsbinding site for residue POV C 906
ChainResidue
CGLU480
CMET525
CSER528
CTYR532
CPHE533
CMET543

site_idAE6
Number of Residues6
Detailsbinding site for residue POV C 907
ChainResidue
CTYR455
DMET583
DLEU587
DLEU590
DPHE591
DCYS636

site_idAE7
Number of Residues8
Detailsbinding site for residue POV C 908
ChainResidue
CTYR437
CPHE440
CPHE561
CGLN563
CMET564
DCYS580
DMET583
DPHE584

site_idAE8
Number of Residues7
Detailsbinding site for residue POV D 901
ChainResidue
AMET583
ALEU587
ALEU590
APHE591
ACYS636
DTYR455
DTYR456

site_idAE9
Number of Residues8
Detailsbinding site for residue POV D 902
ChainResidue
ACYS580
AMET583
APHE584
DTYR437
DPHE440
DPHE561
DGLN563
DMET564

site_idAF1
Number of Residues4
Detailsbinding site for residue POV D 903
ChainResidue
ALYS658
AALA659
APOV909
DTYR633

site_idAF2
Number of Residues9
Detailsbinding site for residue 4DY D 904
ChainResidue
APHE593
ALEU664
ALEU671
APOV909
DSER514
DLEU517
DPHE545
DTHR552
DTYR556

site_idAF3
Number of Residues7
Detailsbinding site for residue POV D 905
ChainResidue
DASN439
DVAL442
DTYR443
DARG493
DGLU515
DPHE518
DTYR557

site_idAF4
Number of Residues4
Detailsbinding site for residue POV D 906
ChainResidue
APOV909
DMET549
DILE575
DLEU576

site_idAF5
Number of Residues6
Detailsbinding site for residue POV D 907
ChainResidue
DGLU480
DMET525
DSER528
DTYR532
DPHE533
DMET543

224931

PDB entries from 2024-09-11

PDB statisticsPDBj update infoContact PDBjnumon