7KXB
Crystal structure of SARS-CoV-2 Nsp3 Macrodomain complex with PARG329
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | binding site for residue XB1 A 201 |
| Chain | Residue |
| A | ASP22 |
| A | LEU126 |
| A | SER128 |
| A | ALA129 |
| A | GLY130 |
| A | PHE132 |
| A | ALA154 |
| A | PHE156 |
| A | HOH309 |
| A | HOH316 |
| A | HOH333 |
| A | ILE23 |
| A | HOH338 |
| A | HOH396 |
| A | ALA38 |
| A | ASN40 |
| A | LYS44 |
| A | GLY46 |
| A | GLY47 |
| A | GLY48 |
| A | VAL49 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue BME A 202 |
| Chain | Residue |
| A | ASN58 |
| A | ASN59 |
| A | TYR68 |
| A | ASN72 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 203 |
| Chain | Residue |
| A | SER7 |
| A | GLY8 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 204 |
| Chain | Residue |
| A | SER7 |
| A | LYS19 |
| A | LYS29 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 205 |
| Chain | Residue |
| A | GLY47 |
| A | GLY48 |
| A | HOH303 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"For ADP-ribosylhydrolase activity","evidences":[{"source":"PubMed","id":"37242344","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"K9N638","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
