7KEU

Cryo-EM structure of the Caspase-1-CARD:ASC-CARD octamer

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006954	biological_process	inflammatory response
A	0042981	biological_process	regulation of apoptotic process
A	0045087	biological_process	innate immune response
B	0006954	biological_process	inflammatory response
B	0042981	biological_process	regulation of apoptotic process
B	0045087	biological_process	innate immune response
C	0006954	biological_process	inflammatory response
C	0042981	biological_process	regulation of apoptotic process
C	0045087	biological_process	innate immune response
D	0006954	biological_process	inflammatory response
D	0042981	biological_process	regulation of apoptotic process
D	0045087	biological_process	innate immune response
E	0004197	molecular_function	cysteine-type endopeptidase activity
E	0006508	biological_process	proteolysis
E	0042981	biological_process	regulation of apoptotic process
F	0004197	molecular_function	cysteine-type endopeptidase activity
F	0006508	biological_process	proteolysis
F	0042981	biological_process	regulation of apoptotic process
G	0004197	molecular_function	cysteine-type endopeptidase activity
G	0006508	biological_process	proteolysis
G	0042981	biological_process	regulation of apoptotic process
H	0004197	molecular_function	cysteine-type endopeptidase activity
H	0006508	biological_process	proteolysis
H	0042981	biological_process	regulation of apoptotic process

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"25847972","evidenceCode":"ECO:0000269"}]}

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Catalytic Information from CSA

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