7JL3
Cryo-EM structure of RIG-I:dsRNA filament in complex with RIPLET PrySpry domain (trimer)
Functional Information from GO Data
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000305 |
| Chain | Residue | Details |
| A | VAL309 | |
| C | VAL309 | |
| E | VAL309 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01125 |
| Chain | Residue | Details |
| C | SER855 | |
| C | LYS858 | |
| C | LYS909 | |
| C | GLU914 | |
| E | SER855 | |
| E | LYS858 | |
| E | LYS909 | |
| E | GLU914 | |
| A | SER855 | |
| A | LYS858 | |
| A | LYS909 | |
| A | GLU914 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | MOD_RES: (Microbial infection) Deamidated asparagine; by herpes simplex virus 1/HHV-1 UL37 => ECO:0000269|PubMed:27866900 |
| Chain | Residue | Details |
| C | LEU540 | |
| C | LEU594 | |
| E | LEU540 | |
| E | LEU594 | |
| A | LEU540 | |
| A | LEU594 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | MOD_RES: Phosphothreonine; by CK2 => ECO:0000269|PubMed:21068236 |
| Chain | Residue | Details |
| C | ALA815 | |
| E | ALA815 | |
| A | ALA815 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | MOD_RES: Phosphoserine; by CK2 => ECO:0000269|PubMed:21068236 |
| Chain | Residue | Details |
| C | THR899 | |
| C | GLY900 | |
| E | THR899 | |
| E | GLY900 | |
| A | THR899 | |
| A | GLY900 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 3 |
| Details | MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861 |
| Chain | Residue | Details |
| C | THR903 | |
| E | THR903 | |
| A | THR903 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 3 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:19484123, ECO:0000269|PubMed:24755855 |
| Chain | Residue | Details |
| C | ILE209 | |
| A | ILE209 | |
| E | ILE209 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 6 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250|UniProtKB:Q6Q899 |
| Chain | Residue | Details |
| A | GLU857 | |
| C | GLU857 | |
| E | GLU857 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 3 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:19484123, ECO:0000269|PubMed:24755855, ECO:0000269|PubMed:28469175 |
| Chain | Residue | Details |
| A | PRO217 | |
| C | PRO217 | |
| E | PRO217 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 3 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:26471729 |
| Chain | Residue | Details |
| A | SER226 | |
| C | SER226 | |
| E | SER226 |
