7BWT
SopD-Rab8 complex structure
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0016020 | cellular_component | membrane |
| A | 0020002 | cellular_component | host cell plasma membrane |
| A | 0030254 | biological_process | protein secretion by the type III secretion system |
| A | 0030430 | cellular_component | host cell cytoplasm |
| A | 0033644 | cellular_component | host cell membrane |
| A | 0044164 | cellular_component | host cell cytosol |
| B | 0003924 | molecular_function | GTPase activity |
| B | 0005525 | molecular_function | GTP binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue PEG A 401 |
| Chain | Residue |
| A | GLU143 |
| A | SER244 |
| A | MET245 |
| A | TYR278 |
| A | HIS282 |
| A | HOH528 |
| B | ALA76 |
| B | ARG79 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue PEG A 402 |
| Chain | Residue |
| B | ARG27 |
| B | LYS153 |
| A | HOH560 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 403 |
| Chain | Residue |
| A | SER213 |
| A | GLY221 |
| A | ASN222 |
| A | PHE223 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 404 |
| Chain | Residue |
| A | LYS85 |
| A | ILE101 |
| A | GLU152 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 405 |
| Chain | Residue |
| A | SER140 |
| A | GLU142 |
| A | GLU143 |
| A | MET189 |
| A | MET190 |
| A | SER244 |
| A | GOL406 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 406 |
| Chain | Residue |
| A | GLU142 |
| A | GLU188 |
| A | MET189 |
| A | GOL405 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue GOL A 407 |
| Chain | Residue |
| A | GLU67 |
| A | HOH525 |
| site_id | AC8 |
| Number of Residues | 21 |
| Details | binding site for residue GDP B 201 |
| Chain | Residue |
| B | ASP16 |
| B | SER17 |
| B | GLY18 |
| B | VAL19 |
| B | GLY20 |
| B | LYS21 |
| B | THR22 |
| B | CYS23 |
| B | PHE33 |
| B | ASN121 |
| B | LYS122 |
| B | ASP124 |
| B | VAL125 |
| B | SER151 |
| B | ALA152 |
| B | LYS153 |
| B | MG202 |
| B | HOH305 |
| B | HOH307 |
| B | HOH309 |
| B | HOH318 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 202 |
| Chain | Residue |
| B | THR22 |
| B | GDP201 |
| B | HOH305 |
| B | HOH307 |
| B | HOH309 |
| B | HOH319 |
| site_id | AD1 |
| Number of Residues | 8 |
| Details | binding site for residue GOL B 203 |
| Chain | Residue |
| B | ARG27 |
| B | PHE28 |
| B | ASP31 |
| B | ARG48 |
| B | ASN155 |
| B | VAL158 |
| B | GLU159 |
| B | GOL206 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 204 |
| Chain | Residue |
| B | LYS10 |
| B | TRP62 |
| B | THR64 |
| B | TYR77 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 205 |
| Chain | Residue |
| A | GLU240 |
| B | THR4 |
| B | SER29 |
| B | GLU30 |
| B | ILE47 |
| B | HOH315 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 206 |
| Chain | Residue |
| B | LYS3 |
| B | SER29 |
| B | ARG48 |
| B | GOL203 |
Functional Information from PROSITE/UniProt
| site_id | PS00675 |
| Number of Residues | 14 |
| Details | SIGMA54_INTERACT_1 Sigma-54 interaction domain ATP-binding region A signature. LLLiGDSGVGKtcV |
| Chain | Residue | Details |
| B | LEU11-VAL24 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 14 |
| Details | Motif: {"description":"Switch 1","evidences":[{"source":"UniProtKB","id":"P62820","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 17 |
| Details | Motif: {"description":"Switch 2","evidences":[{"source":"UniProtKB","id":"P62820","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"21378754","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"27552051","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"3QBT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5SZI","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"27552051","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"5SZI","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"21378754","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27552051","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3QBT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5SZI","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"21378754","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"3QBT","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"21378754","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3QBT","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphothreonine; by LRRK2","evidences":[{"source":"PubMed","id":"26824392","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29125462","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30209220","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30398148","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
