7BVE
Cryo-EM structure of Mycobacterium smegmatis arabinosyltransferase EmbC2-AcpM2 in complex with ethambutol
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0005886 | cellular_component | plasma membrane |
A | 0016757 | molecular_function | glycosyltransferase activity |
A | 0046872 | molecular_function | metal ion binding |
A | 0052636 | molecular_function | arabinosyltransferase activity |
A | 0071555 | biological_process | cell wall organization |
A | 0071766 | biological_process | Actinobacterium-type cell wall biogenesis |
B | 0005886 | cellular_component | plasma membrane |
B | 0016757 | molecular_function | glycosyltransferase activity |
B | 0046872 | molecular_function | metal ion binding |
B | 0052636 | molecular_function | arabinosyltransferase activity |
B | 0071555 | biological_process | cell wall organization |
B | 0071766 | biological_process | Actinobacterium-type cell wall biogenesis |
C | 0000035 | molecular_function | acyl binding |
C | 0000036 | molecular_function | acyl carrier activity |
C | 0005737 | cellular_component | cytoplasm |
C | 0005829 | cellular_component | cytosol |
C | 0006633 | biological_process | fatty acid biosynthetic process |
C | 0009245 | biological_process | lipid A biosynthetic process |
D | 0000035 | molecular_function | acyl binding |
D | 0000036 | molecular_function | acyl carrier activity |
D | 0005737 | cellular_component | cytoplasm |
D | 0005829 | cellular_component | cytosol |
D | 0006633 | biological_process | fatty acid biosynthetic process |
D | 0009245 | biological_process | lipid A biosynthetic process |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | binding site for residue CA A 1101 |
Chain | Residue |
A | ASP929 |
A | ASP931 |
A | ALA933 |
A | HIS936 |
site_id | AC2 |
Number of Residues | 3 |
Details | binding site for residue PO4 A 1102 |
Chain | Residue |
A | ARG383 |
A | THR570 |
A | 95E1103 |
site_id | AC3 |
Number of Residues | 7 |
Details | binding site for residue 95E A 1103 |
Chain | Residue |
A | ILE283 |
A | ARG383 |
A | TRP965 |
A | VAL1004 |
A | PO41102 |
A | ASP279 |
A | TYR282 |
site_id | AC4 |
Number of Residues | 4 |
Details | binding site for residue CA B 1101 |
Chain | Residue |
B | ASP929 |
B | ASP931 |
B | ALA933 |
B | HIS936 |
site_id | AC5 |
Number of Residues | 3 |
Details | binding site for residue PO4 B 1102 |
Chain | Residue |
B | ARG383 |
B | THR570 |
B | 95E1103 |
site_id | AC6 |
Number of Residues | 7 |
Details | binding site for residue 95E B 1103 |
Chain | Residue |
B | ASP279 |
B | TYR282 |
B | ILE283 |
B | ARG383 |
B | TRP965 |
B | VAL1004 |
B | PO41102 |
site_id | AC7 |
Number of Residues | 9 |
Details | binding site for Di-peptide PN7 C 101 and SER C 41 |
Chain | Residue |
A | HIS245 |
A | ARG247 |
A | SER251 |
A | ARG401 |
C | ASP40 |
C | LEU42 |
C | SER43 |
C | MET44 |
C | VAL45 |
site_id | AC8 |
Number of Residues | 9 |
Details | binding site for Di-peptide PN7 D 101 and SER D 41 |
Chain | Residue |
B | HIS245 |
B | ARG247 |
B | SER251 |
B | ARG401 |
D | ASP40 |
D | LEU42 |
D | SER43 |
D | MET44 |
D | VAL45 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | MOD_RES: O-(pantetheine 4'-phosphoryl)serine => ECO:0000255|PROSITE-ProRule:PRU00258 |
Chain | Residue | Details |
C | SER41 | |
D | SER41 |
site_id | SWS_FT_FI2 |
Number of Residues | 4 |
Details | CROSSLNK: Isoglutamyl lysine isopeptide (Lys-Gln) (interchain with Q-Cter in protein Pup) => ECO:0000269|PubMed:20094657 |
Chain | Residue | Details |
C | LYS79 | |
D | LYS79 |