7BT5
Crystal structure of plasmodium LysRS complexing with an antitumor compound
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| A | 0004824 | molecular_function | lysine-tRNA ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| A | 0006430 | biological_process | lysyl-tRNA aminoacylation |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| B | 0004824 | molecular_function | lysine-tRNA ligase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| B | 0006430 | biological_process | lysyl-tRNA aminoacylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | binding site for residue LYS A 601 |
| Chain | Residue |
| A | GLU308 |
| A | GLU346 |
| A | TYR348 |
| A | ASN503 |
| A | TYR505 |
| A | GLU507 |
| A | GLY554 |
| A | F6O602 |
| A | HOH714 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | binding site for residue F6O A 602 |
| Chain | Residue |
| A | ARG330 |
| A | GLU332 |
| A | GLY333 |
| A | THR337 |
| A | HIS338 |
| A | ASN339 |
| A | PRO340 |
| A | PHE342 |
| A | GLU500 |
| A | VAL501 |
| A | LEU502 |
| A | GLY554 |
| A | GLY556 |
| A | ARG559 |
| A | ILE570 |
| A | LYS601 |
| A | HOH722 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue LYS B 601 |
| Chain | Residue |
| B | GLU308 |
| B | GLU346 |
| B | TYR348 |
| B | ASN503 |
| B | TYR505 |
| B | GLU507 |
| B | GLY554 |
| B | HOH713 |
| site_id | AC4 |
| Number of Residues | 17 |
| Details | binding site for residue F6O B 602 |
| Chain | Residue |
| B | ALA287 |
| B | ARG330 |
| B | GLU332 |
| B | GLY333 |
| B | THR337 |
| B | HIS338 |
| B | ASN339 |
| B | PHE342 |
| B | GLU500 |
| B | VAL501 |
| B | LEU502 |
| B | GLY554 |
| B | GLY556 |
| B | ARG559 |
| B | ILE570 |
| B | HOH735 |
| B | HOH747 |
