Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0004879 | molecular_function | nuclear receptor activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| C | 0003677 | molecular_function | DNA binding |
| C | 0004879 | molecular_function | nuclear receptor activity |
| C | 0005634 | cellular_component | nucleus |
| C | 0006355 | biological_process | regulation of DNA-templated transcription |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue F5A A 501 |
| Chain | Residue |
| A | PHE273 |
| A | ALA454 |
| A | ALA455 |
| A | LEU456 |
| A | TYR464 |
| A | CYS276 |
| A | GLN277 |
| A | SER280 |
| A | TYR314 |
| A | HIS440 |
| A | VAL444 |
| A | ILE447 |
| A | LYS448 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue F5A A 502 |
| Chain | Residue |
| A | LEU247 |
| A | LEU254 |
| A | LYS257 |
| A | CYS275 |
| A | THR279 |
| A | ALA333 |
| A | TYR334 |
| A | HOH680 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | binding site for residue F5A C 501 |
| Chain | Residue |
| C | PHE273 |
| C | GLN277 |
| C | SER280 |
| C | TYR314 |
| C | HIS440 |
| C | VAL444 |
| C | ILE447 |
| C | LYS448 |
| C | ALA454 |
| C | ALA455 |
| C | LEU456 |
| C | TYR464 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | binding site for residue F5A C 502 |
| Chain | Residue |
| C | LEU247 |
| C | LYS257 |
| C | CYS275 |
| C | THR279 |
| C | GLU282 |
| C | ALA333 |
| C | TYR334 |
| C | HOH613 |
| C | HOH618 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 454 |
| Details | Domain: {"description":"NR LBD","evidences":[{"source":"PROSITE-ProRule","id":"PRU01189","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 258 |
| Details | Region: {"description":"Required for heterodimerization with RXRA"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"19116277","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3ET1","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Site: {"description":"Essential for heterodimerization with RXRA"} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 8 |
| Details | Motif: {"description":"LXXLL motif 4"} |
