7BQ0
X-ray structure of human PPARalpha ligand binding domain-fenofibric acid-SRC1 coactivator peptide co-crystals obtained by delipidation and co-crystallization
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Peroxisome proliferator-activated receptor alpha | polymer | 273 | 30856.1 | 2 | UniProt (Q07869) Pfam (PF00104) | Homo sapiens | |
| 2 | B, D (B, D) | 15-meric peptide from Nuclear receptor coactivator 1 | polymer | 15 | 1848.2 | 2 | UniProt (Q15788) | Homo sapiens | |
| 3 | E, F, G, H (A, C) | 2-[4-(4-chlorobenzene-1-carbonyl)phenoxy]-2-methylpropanoic acid | non-polymer | 318.8 | 4 | Chemie (F5A) | |||
| 4 | I, J, K (A, C, D) | water | water | 18.0 | 200 | Chemie (HOH) |
Sequence modifications
A, C: 200 - 468 (UniProt: Q07869)
| PDB | External Database | Details |
|---|---|---|
| Gly 196 | - | expression tag |
| Ser 197 | - | expression tag |
| His 198 | - | expression tag |
| Met 199 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 65408.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1275.0 | |
| All* | Total formula weight | 66683.5 |
