Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004713 | molecular_function | protein tyrosine kinase activity |
| A | 0004714 | molecular_function | transmembrane receptor protein tyrosine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| A | 0007169 | biological_process | cell surface receptor protein tyrosine kinase signaling pathway |
| A | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | binding site for residue EDO A 1001 |
| Chain | Residue |
| A | MET810 |
| A | ALA811 |
| A | TRP812 |
| A | ILE815 |
| A | PHE845 |
| A | VAL853 |
| A | ASN856 |
| A | ALA857 |
| A | EDO1002 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 1002 |
| Chain | Residue |
| A | TRP827 |
| A | PHE845 |
| A | TYR869 |
| A | LEU870 |
| A | TRP888 |
| A | EDO1001 |
| A | HOH1111 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 1003 |
| Chain | Residue |
| A | SER892 |
| A | ARG895 |
| A | PRO897 |
| A | HOH1138 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 1004 |
| Chain | Residue |
| A | GLY786 |
| A | VAL804 |
| A | HOH1122 |
| A | HOH1129 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 1005 |
| Chain | Residue |
| A | ASP668 |
| A | HOH1137 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue PO4 A 1006 |
| Chain | Residue |
| A | GLY801 |
| A | ARG802 |
| A | ARG872 |
| A | PRO874 |
| A | ALA875 |
| A | ARG903 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 A 1007 |
| Chain | Residue |
| A | LYS671 |
| A | TRP834 |
| A | PHE845 |
| A | LEU870 |
| A | SER871 |
| A | HOH1130 |
| A | HOH1171 |
| A | HOH1201 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 1008 |
| Chain | Residue |
| A | TRP812 |
| A | GLU813 |
| A | ARG890 |
| A | GLU891 |
| A | SER892 |
| site_id | AC9 |
| Number of Residues | 17 |
| Details | binding site for residue TJW A 1009 |
| Chain | Residue |
| A | ALA653 |
| A | GLU672 |
| A | MET676 |
| A | ILE685 |
| A | THR701 |
| A | ASP702 |
| A | TYR703 |
| A | MET704 |
| A | GLY707 |
| A | PHE762 |
| A | HIS764 |
| A | ILE782 |
| A | ALA783 |
| A | ASP784 |
| A | GLN847 |
| A | HOH1139 |
| A | HOH1220 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 1010 |
| Chain | Residue |
| A | LYS655 |
| A | GLU672 |
| A | HOH1139 |
Functional Information from PROSITE/UniProt
| site_id | PS00109 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. FVHrDLATRNCLV |
| Chain | Residue | Details |
| A | PHE762-VAL774 | |
| site_id | PS00239 |
| Number of Residues | 9 |
| Details | RECEPTOR_TYR_KIN_II Receptor tyrosine kinase class II signature. NLYagdYYR |
| Chain | Residue | Details |
| A | ASN790-ARG798 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP766 | |
| Chain | Residue | Details |
| A | LEU616 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | LYS655 | |
| Chain | Residue | Details |
| A | SER631 | |
| Chain | Residue | Details |
| A | TYR740 | |
| Chain | Residue | Details |
| A | TYR792 | |
| A | TYR796 | |
| A | TYR797 | |
