7AYR
Crystal structure of DPP8 in complex with a 4-oxo-b-lactam based inhibitor, B115
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004177 | molecular_function | aminopeptidase activity |
A | 0005515 | molecular_function | protein binding |
A | 0005737 | cellular_component | cytoplasm |
A | 0005829 | cellular_component | cytosol |
A | 0006508 | biological_process | proteolysis |
A | 0006915 | biological_process | apoptotic process |
A | 0006955 | biological_process | immune response |
A | 0008236 | molecular_function | serine-type peptidase activity |
A | 0008239 | molecular_function | dipeptidyl-peptidase activity |
A | 0043069 | biological_process | negative regulation of programmed cell death |
B | 0004177 | molecular_function | aminopeptidase activity |
B | 0005515 | molecular_function | protein binding |
B | 0005737 | cellular_component | cytoplasm |
B | 0005829 | cellular_component | cytosol |
B | 0006508 | biological_process | proteolysis |
B | 0006915 | biological_process | apoptotic process |
B | 0006955 | biological_process | immune response |
B | 0008236 | molecular_function | serine-type peptidase activity |
B | 0008239 | molecular_function | dipeptidyl-peptidase activity |
B | 0043069 | biological_process | negative regulation of programmed cell death |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 6 |
Details | ACT_SITE: Charge relay system => ECO:0000305|PubMed:12534281, ECO:0000305|PubMed:29382749 |
Chain | Residue | Details |
A | SER755 | |
A | ASP833 | |
A | HIS865 | |
B | SER755 | |
B | ASP833 | |
B | HIS865 |