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7AVV

Crystal structure of SOS1 in complex with compound 9

Functional Information from GO Data
ChainGOidnamespacecontents
A0005085molecular_functionguanyl-nucleotide exchange factor activity
A0007264biological_processsmall GTPase-mediated signal transduction
Functional Information from PDB Data
site_idAC1
Number of Residues3
Detailsbinding site for residue IMD A 1101
ChainResidue
ATYR884
APHE890
AS2W1102

site_idAC2
Number of Residues9
Detailsbinding site for residue S2W A 1102
ChainResidue
AGLU902
AHIS905
AIMD1101
AMET878
AASN879
ATYR884
APHE890
ALYS898
ALEU901

Functional Information from PROSITE/UniProt
site_idPS00720
Number of Residues34
DetailsRASGEF Ras Guanine-nucleotide exchange factors domain signature. VPFfGiyLtNIlkteegnpevlkrhgkel.................INFsK
ChainResidueDetails
AVAL927-LYS960

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PDB entries from 2024-07-10

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