6ZSM

Crystal structure of rsGCaMP double mutant Ile80His/Val116Ile in the ON state (non-illuminated)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005509	molecular_function	calcium ion binding
A	0006091	biological_process	generation of precursor metabolites and energy
A	0008218	biological_process	bioluminescence

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue CA A 501

Chain	Residue
A	ASP432
A	ASP434
A	ASP436
A	GLN438
A	GLU443
A	HOH658

---

site_id	AC2
Number of Residues	6
Details	binding site for residue CA A 502

Chain	Residue
A	THR329
A	GLU334
A	HOH707
A	ASP323
A	ASP325
A	ASP327

---

site_id	AC3
Number of Residues	6
Details	binding site for residue CA A 503

Chain	Residue
A	ASP359
A	ASP361
A	ASP363
A	THR365
A	GLU370
A	HOH641

---

site_id	AC4
Number of Residues	6
Details	binding site for residue CA A 504

Chain	Residue
A	ASP396
A	ASP398
A	ASN400
A	TYR402
A	GLU407
A	HOH686

---

site_id	AC5
Number of Residues	7
Details	binding site for residue CA A 505

Chain	Residue
A	ASP361
A	ASP363
A	ASP367
A	HOH605
A	HOH641
A	HOH758
A	HOH889

---

site_id	AC6
Number of Residues	3
Details	binding site for residue FMT A 506

Chain	Residue
A	HIS112
A	GLY141
A	HOH739

---

site_id	AC7
Number of Residues	3
Details	binding site for residue FMT A 507

Chain	Residue
A	ARG267
A	ARG280
A	GLU282

---

site_id	AC8
Number of Residues	4
Details	binding site for residue FMT A 508

Chain	Residue
A	LYS265
A	ARG267
A	GLU282
A	LYS284

---

site_id	AC9
Number of Residues	4
Details	binding site for residue FMT A 509

Chain	Residue
A	GLU175
A	ASP177
A	ILE281
A	HOH654

---

site_id	AD1
Number of Residues	7
Details	binding site for residue FMT A 510

Chain	Residue
A	GLU163
A	ALA195
A	SER230
A	TYR232
A	LYS237
A	HOH612
A	HOH616

---

site_id	AD2
Number of Residues	3
Details	binding site for residue FMT A 511

Chain	Residue
A	ASP363
A	FMT512
A	HOH758

---

site_id	AD3
Number of Residues	7
Details	binding site for residue FMT A 512

Chain	Residue
A	TYR93
A	ASP327
A	THR329
A	FMT511
A	HOH638
A	HOH646
A	HOH866

---

site_id	AD4
Number of Residues	3
Details	binding site for residue FMT A 513

Chain	Residue
A	HIS183
A	HOH694
A	HOH729

---

site_id	AD5
Number of Residues	1
Details	binding site for residue FMT A 514

Chain	Residue
A	GLN70

---

site_id	AD6
Number of Residues	3
Details	binding site for residue FMT A 515

Chain	Residue
A	VAL159
A	SER160
A	GLN238

---

site_id	AD7
Number of Residues	5
Details	binding site for residue FMT A 516

Chain	Residue
A	LEU60
A	LYS79
A	HOH613
A	HOH646
A	HOH660

---

site_id	AD8
Number of Residues	6
Details	binding site for residue FMT A 517

Chain	Residue
A	GLU126
A	LYS127
A	ARG128
A	HIS130
A	HOH648
A	HOH927

---

site_id	AD9
Number of Residues	4
Details	binding site for residue FMT A 518

Chain	Residue
A	GLN344
A	GLU390
A	HOH715
A	HOH740

---

site_id	AE1
Number of Residues	5
Details	binding site for residue FMT A 519

Chain	Residue
A	PRO109
A	ASP110
A	ARG231
A	HOH606
A	HOH672

---

site_id	AE2
Number of Residues	6
Details	binding site for residue EDO A 520

Chain	Residue
A	HIS80
A	ARG81
A	ARG377
A	TYR381
A	HOH760
A	HOH761

---

site_id	AE3
Number of Residues	5
Details	binding site for residue EDO A 521

Chain	Residue
A	HOH620
A	ARG52
A	ASP383
A	ILE388
A	MET448

---

site_id	AE4
Number of Residues	4
Details	binding site for residue EDO A 522

Chain	Residue
A	TYR95
A	GLU253
A	HOH626
A	HOH673

---

site_id	AE5
Number of Residues	2
Details	binding site for residue EDO A 523

Chain	Residue
A	HOH647
A	HOH847

---

site_id	AE6
Number of Residues	7
Details	binding site for residue EDO A 524

Chain	Residue
A	LYS79
A	ARG81
A	LEU91
A	SER384
A	GLU386
A	GLU387
A	HOH655

---

Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DKDGDGTITtkEL

Chain	Residue	Details
A	ASP325-THR337
A	ASP361-THR373
A	ASP398-HIS410
A	ASP434-GLN446

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI6
Number of Residues	1
Details	Modified residue: {"description":"(Z)-2,3-didehydrotyrosine","evidences":[{"source":"PubMed","id":"8448132","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	2
Details	Cross-link: {"description":"5-imidazolinone (Ser-Gly)","evidences":[{"source":"PubMed","id":"8448132","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---