6Z86

human GTP cyclohydrolase I in complex with 7-deaza-GTP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003934	molecular_function	GTP cyclohydrolase I activity
A	0046654	biological_process	tetrahydrofolate biosynthetic process
B	0003934	molecular_function	GTP cyclohydrolase I activity
B	0046654	biological_process	tetrahydrofolate biosynthetic process
C	0003934	molecular_function	GTP cyclohydrolase I activity
C	0046654	biological_process	tetrahydrofolate biosynthetic process
D	0003934	molecular_function	GTP cyclohydrolase I activity
D	0046654	biological_process	tetrahydrofolate biosynthetic process
E	0003934	molecular_function	GTP cyclohydrolase I activity
E	0046654	biological_process	tetrahydrofolate biosynthetic process
F	0003934	molecular_function	GTP cyclohydrolase I activity
F	0046654	biological_process	tetrahydrofolate biosynthetic process
G	0003934	molecular_function	GTP cyclohydrolase I activity
G	0046654	biological_process	tetrahydrofolate biosynthetic process
H	0003934	molecular_function	GTP cyclohydrolase I activity
H	0046654	biological_process	tetrahydrofolate biosynthetic process
I	0003934	molecular_function	GTP cyclohydrolase I activity
I	0046654	biological_process	tetrahydrofolate biosynthetic process
J	0003934	molecular_function	GTP cyclohydrolase I activity
J	0046654	biological_process	tetrahydrofolate biosynthetic process
K	0003934	molecular_function	GTP cyclohydrolase I activity
K	0046654	biological_process	tetrahydrofolate biosynthetic process
L	0003934	molecular_function	GTP cyclohydrolase I activity
L	0046654	biological_process	tetrahydrofolate biosynthetic process
M	0003934	molecular_function	GTP cyclohydrolase I activity
M	0046654	biological_process	tetrahydrofolate biosynthetic process
N	0003934	molecular_function	GTP cyclohydrolase I activity
N	0046654	biological_process	tetrahydrofolate biosynthetic process
O	0003934	molecular_function	GTP cyclohydrolase I activity
O	0046654	biological_process	tetrahydrofolate biosynthetic process
P	0003934	molecular_function	GTP cyclohydrolase I activity
P	0046654	biological_process	tetrahydrofolate biosynthetic process
Q	0003934	molecular_function	GTP cyclohydrolase I activity
Q	0046654	biological_process	tetrahydrofolate biosynthetic process
R	0003934	molecular_function	GTP cyclohydrolase I activity
R	0046654	biological_process	tetrahydrofolate biosynthetic process
S	0003934	molecular_function	GTP cyclohydrolase I activity
S	0046654	biological_process	tetrahydrofolate biosynthetic process
T	0003934	molecular_function	GTP cyclohydrolase I activity
T	0046654	biological_process	tetrahydrofolate biosynthetic process

Functional Information from PROSITE/UniProt

site_id	PS00859
Number of Residues	17
Details	GTP_CYCLOHYDROL_1_1 GTP cyclohydrolase I signature 1. EMVivKDIdmfSmCEHH

Chain	Residue	Details
A	GLU128-HIS144

---

site_id	PS00860
Number of Residues	11
Details	GTP_CYCLOHYDROL_1_2 GTP cyclohydrolase I signature 2. SrRlQVQERLT

Chain	Residue	Details
A	SER176-THR186

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	60
Details	Binding site: {"evidences":[{"source":"PubMed","id":"11087827","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	19
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	20
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17704208","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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