Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004672 | molecular_function | protein kinase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0006468 | biological_process | protein phosphorylation |
B | 0004672 | molecular_function | protein kinase activity |
B | 0005524 | molecular_function | ATP binding |
B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 11 |
Details | binding site for residue PO4 A 501 |
Chain | Residue |
A | HIS330 |
B | THR332 |
B | THR333 |
A | THR332 |
A | THR333 |
A | HOH601 |
A | HOH614 |
A | HOH615 |
A | HOH618 |
A | HOH870 |
B | HIS330 |
site_id | AC2 |
Number of Residues | 9 |
Details | binding site for residue PO4 A 502 |
Chain | Residue |
A | ARG402 |
A | LYS405 |
A | HOH605 |
A | HOH713 |
A | HOH724 |
A | HOH785 |
A | HOH809 |
B | HIS328 |
B | GLU329 |
site_id | AC3 |
Number of Residues | 8 |
Details | binding site for residue PO4 A 503 |
Chain | Residue |
A | ARG189 |
A | ARG189 |
A | LYS193 |
A | LYS193 |
A | TYR194 |
A | TYR194 |
A | HOH606 |
A | HOH606 |
site_id | AC4 |
Number of Residues | 7 |
Details | binding site for residue EDO A 504 |
Chain | Residue |
A | LEU412 |
A | TRP414 |
A | TRP414 |
A | HOH617 |
A | HOH617 |
A | HOH699 |
A | HOH699 |
site_id | AC5 |
Number of Residues | 5 |
Details | binding site for residue EDO A 505 |
Chain | Residue |
A | ARG451 |
A | ALA458 |
A | GLN459 |
A | ARG460 |
A | GLU465 |
site_id | AC6 |
Number of Residues | 7 |
Details | binding site for residue EDO A 506 |
Chain | Residue |
A | PHE371 |
A | THR372 |
A | LEU373 |
A | ASN427 |
A | TYR434 |
A | HOH746 |
A | HOH876 |
site_id | AC7 |
Number of Residues | 4 |
Details | binding site for residue EDO A 507 |
Chain | Residue |
A | HOH604 |
B | ASN190 |
B | GLY192 |
B | ARG195 |
site_id | AC8 |
Number of Residues | 5 |
Details | binding site for residue EDO A 508 |
Chain | Residue |
A | GLU348 |
A | HOH662 |
A | HOH732 |
B | HIS330 |
B | HIS331 |
site_id | AC9 |
Number of Residues | 6 |
Details | binding site for residue EDO A 509 |
Chain | Residue |
A | SER132 |
A | SER135 |
A | VAL145 |
A | ASP150 |
A | TRP151 |
A | NA518 |
site_id | AD1 |
Number of Residues | 3 |
Details | binding site for residue EDO A 510 |
Chain | Residue |
A | GLN153 |
A | GLU154 |
B | HIS303 |
site_id | AD2 |
Number of Residues | 2 |
Details | binding site for residue EDO A 511 |
Chain | Residue |
A | ARG199 |
A | ASN203 |
site_id | AD3 |
Number of Residues | 4 |
Details | binding site for residue EDO A 512 |
Chain | Residue |
A | GLY322 |
A | ALA324 |
A | HOH649 |
A | HOH691 |
site_id | AD4 |
Number of Residues | 3 |
Details | binding site for residue EDO A 513 |
Chain | Residue |
A | GLU295 |
A | PHE296 |
A | HOH718 |
site_id | AD5 |
Number of Residues | 4 |
Details | binding site for residue EDO A 514 |
Chain | Residue |
A | ARG422 |
A | HOH640 |
B | ASP438 |
B | SER439 |
site_id | AD6 |
Number of Residues | 5 |
Details | binding site for residue EDO A 515 |
Chain | Residue |
A | SER418 |
A | SER419 |
A | ASP420 |
A | HOH765 |
A | HOH788 |
site_id | AD7 |
Number of Residues | 6 |
Details | binding site for residue EDO A 516 |
Chain | Residue |
A | HIS330 |
A | HIS331 |
A | HOH613 |
A | HOH918 |
B | GLU348 |
B | ARG402 |
site_id | AD8 |
Number of Residues | 7 |
Details | binding site for residue NA A 517 |
Chain | Residue |
A | GLN278 |
A | THR280 |
A | THR325 |
A | PHE326 |
A | ASP327 |
A | GLN353 |
A | HOH695 |
site_id | AD9 |
Number of Residues | 4 |
Details | binding site for residue NA A 518 |
Chain | Residue |
A | HOH860 |
A | SER132 |
A | SER135 |
A | EDO509 |
site_id | AE1 |
Number of Residues | 11 |
Details | binding site for residue PQ5 A 519 |
Chain | Residue |
A | ALA184 |
A | LYS186 |
A | PHE236 |
A | GLU237 |
A | LEU238 |
A | LEU239 |
A | ASP320 |
A | HOH675 |
A | HOH698 |
A | HOH717 |
A | HOH831 |
site_id | AE2 |
Number of Residues | 9 |
Details | binding site for residue PO4 B 501 |
Chain | Residue |
A | HOH807 |
B | ARG402 |
B | LYS403 |
B | LYS405 |
B | HOH602 |
B | HOH614 |
B | HOH706 |
B | HOH763 |
B | HOH766 |
site_id | AE3 |
Number of Residues | 7 |
Details | binding site for residue PO4 B 502 |
Chain | Residue |
B | ARG189 |
B | ARG189 |
B | LYS193 |
B | LYS193 |
B | TYR194 |
B | TYR194 |
B | HOH833 |
site_id | AE4 |
Number of Residues | 5 |
Details | binding site for residue EDO B 503 |
Chain | Residue |
B | GLY322 |
B | ALA324 |
B | HOH613 |
B | HOH728 |
B | HOH734 |
site_id | AE5 |
Number of Residues | 4 |
Details | binding site for residue EDO B 504 |
Chain | Residue |
B | HIS328 |
B | HOH640 |
B | HOH750 |
B | HOH790 |
site_id | AE6 |
Number of Residues | 6 |
Details | binding site for residue EDO B 505 |
Chain | Residue |
B | ALA458 |
B | GLN459 |
B | ARG460 |
B | GLU465 |
B | HOH635 |
B | HOH799 |
site_id | AE7 |
Number of Residues | 2 |
Details | binding site for residue EDO B 506 |
Chain | Residue |
B | ASP224 |
B | TRP225 |
site_id | AE8 |
Number of Residues | 5 |
Details | binding site for residue EDO B 507 |
Chain | Residue |
A | ASP438 |
B | ASP447 |
B | ARG450 |
B | ARG451 |
B | GLU454 |
site_id | AE9 |
Number of Residues | 2 |
Details | binding site for residue EDO B 508 |
Chain | Residue |
B | SER395 |
B | HOH624 |
site_id | AF1 |
Number of Residues | 6 |
Details | binding site for residue EDO B 509 |
Chain | Residue |
B | SER132 |
B | VAL136 |
B | VAL145 |
B | ASP150 |
B | TRP151 |
B | HIS377 |
site_id | AF2 |
Number of Residues | 9 |
Details | binding site for residue EDO B 510 |
Chain | Residue |
B | ARG147 |
B | LEU247 |
B | PHE252 |
B | GLU366 |
B | GLY370 |
B | PHE371 |
B | THR372 |
B | HOH601 |
B | HOH772 |
site_id | AF3 |
Number of Residues | 4 |
Details | binding site for residue EDO B 511 |
Chain | Residue |
B | LYS140 |
B | ILE334 |
B | ALA336 |
B | HOH607 |
site_id | AF4 |
Number of Residues | 5 |
Details | binding site for residue EDO B 512 |
Chain | Residue |
B | ASP327 |
B | GLN353 |
B | HOH637 |
B | HOH658 |
B | HOH694 |
site_id | AF5 |
Number of Residues | 3 |
Details | binding site for residue EDO B 513 |
Chain | Residue |
B | PHE371 |
B | LEU373 |
B | TYR434 |
site_id | AF6 |
Number of Residues | 5 |
Details | binding site for residue EDO B 514 |
Chain | Residue |
B | ARG380 |
B | TRP414 |
B | ASP415 |
B | SER418 |
B | GLY421 |
site_id | AF7 |
Number of Residues | 8 |
Details | binding site for residue NA B 515 |
Chain | Residue |
B | GLN278 |
B | LEU279 |
B | THR280 |
B | THR325 |
B | PHE326 |
B | ASP327 |
B | GLN353 |
B | HOH694 |
site_id | AF8 |
Number of Residues | 11 |
Details | binding site for residue PQ5 B 516 |
Chain | Residue |
B | VAL170 |
B | ALA184 |
B | LYS186 |
B | PHE236 |
B | GLU237 |
B | LEU238 |
B | LEU239 |
B | ASP320 |
B | HOH687 |
B | HOH697 |
B | HOH817 |
Functional Information from PROSITE/UniProt
site_id | PS00107 |
Number of Residues | 25 |
Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGEGTFGKVVeCldhargksq.........VALK |
Chain | Residue | Details |
A | LEU162-LYS186 | |
site_id | PS00108 |
Number of Residues | 13 |
Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. LtHtDLKpeNILF |
Chain | Residue | Details |
A | LEU279-PHE291 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | ASP283 | |
B | ASP283 | |
Chain | Residue | Details |
A | LEU162 | |
A | LYS186 | |
B | LEU162 | |
B | LYS186 | |
Chain | Residue | Details |
A | SER135 | |
B | SER135 | |