Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 501 |
| Chain | Residue |
| A | TRP225 |
| A | IOD507 |
| A | HOH676 |
| B | LYS206 |
| B | TRP225 |
| B | IOD510 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 502 |
| Chain | Residue |
| A | LYS248 |
| A | ASN242 |
| A | PHE244 |
| A | GLU245 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 503 |
| Chain | Residue |
| A | ARG451 |
| A | GLU454 |
| A | GLN459 |
| A | ARG460 |
| A | ILE461 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 504 |
| Chain | Residue |
| A | ARG402 |
| A | HOH776 |
| A | HOH791 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 505 |
| Chain | Residue |
| A | ARG199 |
| A | TRP225 |
| B | ARG199 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | binding site for residue CL A 506 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | binding site for residue IOD A 507 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | binding site for residue IOD A 508 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 509 |
| Chain | Residue |
| A | HIS143 |
| A | LEU144 |
| A | ILE187 |
| site_id | AD1 |
| Number of Residues | 1 |
| Details | binding site for residue IOD A 511 |
| site_id | AD2 |
| Number of Residues | 1 |
| Details | binding site for residue IOD A 512 |
| site_id | AD3 |
| Number of Residues | 2 |
| Details | binding site for residue IOD A 513 |
| Chain | Residue |
| A | ARG131 |
| A | GLN153 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue IOD A 514 |
| Chain | Residue |
| A | ASN203 |
| B | ASN227 |
| B | HOH716 |
| site_id | AD5 |
| Number of Residues | 14 |
| Details | binding site for residue Q8T A 515 |
| Chain | Residue |
| A | LEU162 |
| A | PHE167 |
| A | VAL170 |
| A | ALA184 |
| A | GLU237 |
| A | LEU239 |
| A | ASN242 |
| A | GLU245 |
| A | GLU287 |
| A | ASN288 |
| A | LEU290 |
| A | ASP320 |
| A | HOH691 |
| A | HOH737 |
| site_id | AD6 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 501 |
| Chain | Residue |
| B | LYS248 |
| B | PHE252 |
| B | HOH612 |
| site_id | AD7 |
| Number of Residues | 2 |
| Details | binding site for residue EDO B 502 |
| Chain | Residue |
| B | CYS146 |
| B | ASN161 |
| site_id | AD8 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 503 |
| Chain | Residue |
| B | ASN242 |
| B | PHE244 |
| B | GLU245 |
| B | LYS248 |
| B | Q8T515 |
| site_id | AD9 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 504 |
| Chain | Residue |
| B | GLU378 |
| B | ARG380 |
| B | GLU381 |
| B | TRP414 |
| B | ASP415 |
| B | SER418 |
| site_id | AE1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 505 |
| Chain | Residue |
| B | ARG402 |
| B | HOH779 |
| B | HOH842 |
| site_id | AE2 |
| Number of Residues | 1 |
| Details | binding site for residue CL B 506 |
| site_id | AE3 |
| Number of Residues | 2 |
| Details | binding site for residue IOD B 507 |
| Chain | Residue |
| B | ARG131 |
| B | GLN153 |
| site_id | AE4 |
| Number of Residues | 3 |
| Details | binding site for residue CL B 508 |
| Chain | Residue |
| B | HIS143 |
| B | LEU144 |
| B | ILE187 |
| site_id | AE5 |
| Number of Residues | 2 |
| Details | binding site for residue IOD B 509 |
| Chain | Residue |
| B | HOH752 |
| B | HOH785 |
| site_id | AE6 |
| Number of Residues | 2 |
| Details | binding site for residue IOD B 510 |
| Chain | Residue |
| A | EDO501 |
| B | SER223 |
| site_id | AE7 |
| Number of Residues | 2 |
| Details | binding site for residue IOD B 511 |
| Chain | Residue |
| B | TRP414 |
| B | HOH860 |
| site_id | AE8 |
| Number of Residues | 1 |
| Details | binding site for residue IOD B 512 |
| site_id | AE9 |
| Number of Residues | 1 |
| Details | binding site for residue IOD B 513 |
| site_id | AF1 |
| Number of Residues | 4 |
| Details | binding site for residue IOD B 514 |
| Chain | Residue |
| A | GLN153 |
| A | ASN227 |
| B | ASN203 |
| B | LYS206 |
| site_id | AF2 |
| Number of Residues | 15 |
| Details | binding site for residue Q8T B 515 |
| Chain | Residue |
| B | HOH720 |
| B | LEU162 |
| B | GLU164 |
| B | PHE167 |
| B | ALA184 |
| B | PHE236 |
| B | GLU237 |
| B | LEU239 |
| B | ASN242 |
| B | GLU287 |
| B | ASN288 |
| B | LEU290 |
| B | EDO503 |
| B | HOH604 |
| B | HOH701 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 25 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGEGTFGKVVeCldhargksq.........VALK |
| Chain | Residue | Details |
| A | LEU162-LYS186 | |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. LtHtDLKpeNILF |
| Chain | Residue | Details |
| A | LEU279-PHE291 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | LEU431 | |
| B | LEU431 | |
| Chain | Residue | Details |
| A | SER310 | |
| A | ILE334 | |
| B | SER310 | |
| B | ILE334 | |
| Chain | Residue | Details |
| A | ARG155 | |
| B | ARG155 | |
| Chain | Residue | Details |
| A | GLU157 | |
| B | GLU157 | |
| Chain | Residue | Details |
| A | ALA197 | |
| A | ARG199 | |
| B | ALA197 | |
| B | ARG199 | |
| Chain | Residue | Details |
| A | ASN215 | |
| B | ASN215 | |
| Chain | Residue | Details |
| A | ASP224 | |
| A | PHE226 | |
| B | ASP224 | |
| B | PHE226 | |
| Chain | Residue | Details |
| A | ASP283 | |
| B | ASP283 | |
