Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue Q7K A 501 |
| Chain | Residue |
| A | LEU167 |
| A | HOH717 |
| A | HOH823 |
| A | HOH908 |
| A | GLY168 |
| A | ALA189 |
| A | PHE241 |
| A | GLU242 |
| A | LEU244 |
| A | ASP250 |
| A | ASN293 |
| A | LEU295 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 502 |
| Chain | Residue |
| A | VAL156 |
| A | SER158 |
| A | ALA159 |
| A | ARG431 |
| A | ALA432 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 503 |
| Chain | Residue |
| A | SER158 |
| A | ARG160 |
| A | GLU229 |
| A | PHE257 |
| A | HOH821 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 504 |
| Chain | Residue |
| A | LEU213 |
| A | ASN214 |
| A | ASP217 |
| A | SER220 |
| A | CYS224 |
| A | VAL225 |
| A | PHE278 |
| A | HOH623 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 505 |
| Chain | Residue |
| A | LEU243 |
| A | LEU244 |
| A | VAL297 |
| A | GLN298 |
| A | SER299 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 506 |
| Chain | Residue |
| A | ASP288 |
| A | SER328 |
| A | SER341 |
| A | THR342 |
| A | HOH784 |
| A | HOH906 |
| A | HOH936 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 507 |
| Chain | Residue |
| A | GLU201 |
| A | ARG204 |
| A | SER205 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 508 |
| Chain | Residue |
| A | GLU232 |
| A | HIS233 |
| A | HIS234 |
| A | LEU258 |
| A | HOH635 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 509 |
| Chain | Residue |
| A | PHE251 |
| A | ASN255 |
| A | LEU258 |
| A | PRO259 |
| A | PHE260 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 510 |
| Chain | Residue |
| A | ARG465 |
| A | GLU470 |
| A | HOH650 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 511 |
| Chain | Residue |
| A | ASP332 |
| A | GLN358 |
| A | HOH608 |
| A | HOH703 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 512 |
| Chain | Residue |
| A | TRP419 |
| A | ASP420 |
| A | SER423 |
| A | EDO515 |
| A | HOH845 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 513 |
| Chain | Residue |
| A | ASP383 |
| A | GLU386 |
| A | ALA425 |
| A | HOH610 |
| A | HOH805 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 514 |
| Chain | Residue |
| A | ARG223 |
| A | LYS267 |
| A | GLN271 |
| A | HOH854 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 515 |
| Chain | Residue |
| A | ASP418 |
| A | ASP420 |
| A | EDO512 |
| A | HOH618 |
| site_id | AD7 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 516 |
| Chain | Residue |
| A | ARG261 |
| A | ASP444 |
| A | HIS447 |
| site_id | AD8 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 517 |
| Chain | Residue |
| A | ARG343 |
| A | ARG346 |
| A | HIS382 |
| A | SER384 |
| A | HIS387 |
| A | HOH605 |
| A | HOH620 |
| A | HOH811 |
| site_id | AD9 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 518 |
| Chain | Residue |
| A | GLU162 |
| A | HIS181 |
| A | SER424 |
| A | ALA425 |
| A | TYR428 |
| A | HOH691 |
| site_id | AE1 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 519 |
| Chain | Residue |
| A | ASP333 |
| A | ASP333 |
| A | GLU334 |
| A | GLU334 |
| A | HOH601 |
| A | HOH647 |
| A | HOH647 |
| A | ASP332 |
| A | ASP332 |
| site_id | AE2 |
| Number of Residues | 7 |
| Details | binding site for residue NA A 520 |
| Chain | Residue |
| A | GLU446 |
| A | ARG449 |
| A | PRO475 |
| A | PHE476 |
| A | ASP478 |
| A | LEU479 |
| A | HOH822 |
| site_id | AE3 |
| Number of Residues | 9 |
| Details | binding site for residue EDO A 521 |
| Chain | Residue |
| A | ARG393 |
| A | GLU421 |
| A | GLU421 |
| A | HIS422 |
| A | HIS422 |
| A | SER430 |
| A | SER430 |
| A | HOH641 |
| A | HOH641 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 25 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGEGAFGKVVeCidhkaggrh.........VAVK |
| Chain | Residue | Details |
| A | LEU167-LYS191 | |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. LtHtDLKpeNILF |
| Chain | Residue | Details |
| A | LEU284-PHE296 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP288 | |
| Chain | Residue | Details |
| A | LYS191 | |
| A | LEU167 | |
