Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0002001 | biological_process | renin secretion into blood stream |
| A | 0002281 | biological_process | macrophage activation involved in immune response |
| A | 0004930 | molecular_function | G protein-coupled receptor activity |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0007186 | biological_process | G protein-coupled receptor signaling pathway |
| A | 0016020 | cellular_component | membrane |
| A | 0038023 | molecular_function | signaling receptor activity |
| A | 0042593 | biological_process | glucose homeostasis |
| A | 0050729 | biological_process | positive regulation of inflammatory response |
| A | 0050921 | biological_process | positive regulation of chemotaxis |
| A | 0051592 | biological_process | response to calcium ion |
| A | 0060177 | biological_process | regulation of angiotensin metabolic process |
| A | 0097009 | biological_process | energy homeostasis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue Q4T A 401 |
| Chain | Residue |
| A | TYR26 |
| A | TYR244 |
| A | ARG276 |
| A | PHE280 |
| A | HOH523 |
| A | LEU75 |
| A | SER78 |
| A | TYR79 |
| A | TRP84 |
| A | ASN94 |
| A | ARG95 |
| A | LEU98 |
| A | CYS168 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residue OLC A 402 |
| Chain | Residue |
| A | TYR57 |
| A | PHE111 |
| A | ASP115 |
| A | LEU118 |
| A | LEU129 |
| A | PHE134 |
| A | ILE138 |
| A | OLC403 |
| A | OLC407 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue OLC A 403 |
| Chain | Residue |
| A | TYR117 |
| A | LEU118 |
| A | LYS121 |
| A | LEU137 |
| A | PHE202 |
| A | OLC402 |
| A | OLC407 |
| A | HOH527 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue OLC A 404 |
| Chain | Residue |
| A | PHE156 |
| A | THR158 |
| A | ASN176 |
| A | TYR179 |
| A | SER180 |
| A | TYR183 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue OLC A 405 |
| Chain | Residue |
| A | LYS49 |
| A | TRP51 |
| A | ASN60 |
| A | LYS132 |
| A | TRP143 |
| A | OLC408 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue OLC A 406 |
| Chain | Residue |
| A | ILE63 |
| A | CYS70 |
| A | SER93 |
| A | ASN94 |
| A | OLC413 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | binding site for residue OLC A 407 |
| Chain | Residue |
| A | VAL144 |
| A | LEU145 |
| A | ILE194 |
| A | SER197 |
| A | VAL198 |
| A | TYR204 |
| A | OLC402 |
| A | OLC403 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue OLC A 408 |
| Chain | Residue |
| A | LEU45 |
| A | MET48 |
| A | TRP51 |
| A | OLC405 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue OLC A 409 |
| Chain | Residue |
| A | LEU185 |
| A | THR188 |
| A | HIS245 |
| A | ASN249 |
| A | ALA253 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue OLC A 410 |
| Chain | Residue |
| A | LYS178 |
| A | LEU181 |
| A | ILE182 |
| A | LEU185 |
| site_id | AD2 |
| Number of Residues | 7 |
| Details | binding site for residue OLC A 411 |
| Chain | Residue |
| A | TYR21 |
| A | PHE25 |
| A | MET247 |
| A | ILE268 |
| A | LEU271 |
| A | THR275 |
| A | OLC412 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue OLC A 412 |
| Chain | Residue |
| A | TRP10 |
| A | TYR20 |
| A | CYS263 |
| A | ALA267 |
| A | OLC411 |
| A | HOH533 |
| site_id | AD4 |
| Number of Residues | 9 |
| Details | binding site for residue OLC A 413 |
| Chain | Residue |
| A | TYR86 |
| A | GLY87 |
| A | ASP88 |
| A | VAL89 |
| A | LEU90 |
| A | TYR96 |
| A | VAL97 |
| A | OLC406 |
| B | GLY17 |
| site_id | AD5 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 414 |
| Chain | Residue |
| A | HIS127 |
| A | HIS127 |
| A | ILE128 |
| A | ILE128 |
| A | LEU129 |
| A | LEU129 |
| site_id | AD6 |
| Number of Residues | 1 |
| Details | binding site for residue CL A 415 |
Functional Information from PROSITE/UniProt
| site_id | PS00237 |
| Number of Residues | 17 |
| Details | G_PROTEIN_RECEP_F1_1 G-protein coupled receptors family 1 signature. TSIlFLTFISIDRYLlM |
| Chain | Residue | Details |
| A | THR104-MET120 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=1 => ECO:0000255 |
| Chain | Residue | Details |
| A | ILE28-MET48 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 60 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000255 |
| Chain | Residue | Details |
| A | LYS49-ASN55 | |
| A | LYS121-GLU133 | |
| A | TYR203-PRO226 | |
| A | ARG298-LEU317 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=2 => ECO:0000255 |
| Chain | Residue | Details |
| A | VAL56-ILE76 | |
| site_id | SWS_FT_FI4 |
| Number of Residues | 76 |
| Details | TOPO_DOM: Extracellular => ECO:0000255 |
| Chain | Residue | Details |
| A | ARG77-HIS99 | |
| A | THR155-LEU181 | |
| A | ARG248-ARG276 | |
| site_id | SWS_FT_FI5 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=3 => ECO:0000255 |
| Chain | Residue | Details |
| A | ALA100-MET120 | |
| site_id | SWS_FT_FI6 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=4 => ECO:0000255 |
| Chain | Residue | Details |
| A | PHE134-LEU154 | |
| site_id | SWS_FT_FI7 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=5 => ECO:0000255 |
| Chain | Residue | Details |
| A | ILE182-PHE202 | |
| site_id | SWS_FT_FI8 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=6 => ECO:0000255 |
| Chain | Residue | Details |
| A | LEU227-MET247 | |
| site_id | SWS_FT_FI9 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=7 => ECO:0000255 |
| Chain | Residue | Details |
| A | PRO277-PHE297 | |
| site_id | SWS_FT_FI10 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
