Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 28 |
| Details | binding site for residue APR A 201 |
| Chain | Residue |
| A | ASP22 |
| A | ALA50 |
| A | LEU126 |
| A | SER128 |
| A | ALA129 |
| A | GLY130 |
| A | ILE131 |
| A | PHE132 |
| A | ALA154 |
| A | PHE156 |
| A | HOH301 |
| A | ILE23 |
| A | HOH302 |
| A | HOH304 |
| A | HOH309 |
| A | HOH310 |
| A | HOH320 |
| A | HOH321 |
| A | HOH325 |
| A | HOH337 |
| A | HOH338 |
| A | ALA38 |
| A | ASN40 |
| A | LYS44 |
| A | GLY46 |
| A | GLY47 |
| A | GLY48 |
| A | VAL49 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 202 |
| Chain | Residue |
| A | SER7 |
| A | GLY8 |
| A | TYR9 |
| A | HOH329 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 203 |
| Chain | Residue |
| A | GLY8 |
| A | LYS19 |
| A | ASN20 |
| A | TYR161 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 204 |
| Chain | Residue |
| A | ALA134 |
| A | ASP135 |
| E | PRO74 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 205 |
| Chain | Residue |
| A | ALA129 |
| A | GLY130 |
| A | GLY133 |
| A | ALA134 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 206 |
| Chain | Residue |
| A | ARG148 |
| D | LEU108 |
| D | SER111 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 207 |
| Chain | Residue |
| A | GLU114 |
| A | ASN115 |
| D | ASN115 |
| D | EDO203 |
| D | HOH313 |
| site_id | AC8 |
| Number of Residues | 24 |
| Details | binding site for residue APR B 201 |
| Chain | Residue |
| B | ASP22 |
| B | ILE23 |
| B | ALA38 |
| B | ASN40 |
| B | LYS44 |
| B | GLY46 |
| B | GLY47 |
| B | GLY48 |
| B | VAL49 |
| B | ALA50 |
| B | LEU126 |
| B | SER128 |
| B | ALA129 |
| B | GLY130 |
| B | ILE131 |
| B | PHE132 |
| B | ALA154 |
| B | PHE156 |
| B | HOH301 |
| B | HOH304 |
| B | HOH306 |
| B | HOH308 |
| B | HOH313 |
| B | HOH314 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 202 |
| Chain | Residue |
| B | LYS44 |
| B | HIS45 |
| B | GLN62 |
| E | ALA134 |
| E | ASP135 |
| E | PRO136 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 203 |
| Chain | Residue |
| B | ASP67 |
| B | TYR68 |
| B | THR71 |
| C | TYR9 |
| C | LEU10 |
| C | LYS11 |
| site_id | AD2 |
| Number of Residues | 27 |
| Details | binding site for residue APR C 201 |
| Chain | Residue |
| C | ALA129 |
| C | GLY130 |
| C | ILE131 |
| C | PHE132 |
| C | ALA154 |
| C | PHE156 |
| C | HOH305 |
| C | HOH312 |
| C | HOH313 |
| C | HOH320 |
| C | HOH323 |
| C | HOH324 |
| C | HOH327 |
| C | HOH329 |
| C | HOH336 |
| C | ASP22 |
| C | ILE23 |
| C | ALA38 |
| C | ASN40 |
| C | LYS44 |
| C | GLY46 |
| C | GLY47 |
| C | GLY48 |
| C | VAL49 |
| C | ALA50 |
| C | LEU126 |
| C | SER128 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue MG C 202 |
| Chain | Residue |
| C | GLY0 |
| C | HIS1 |
| C | GLU120 |
| E | HIS138 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue EDO C 203 |
| Chain | Residue |
| C | GLY8 |
| C | LYS19 |
| C | ASN20 |
| C | TYR161 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue EDO C 204 |
| Chain | Residue |
| B | ASP67 |
| C | PHE6 |
| C | SER7 |
| C | GLY8 |
| C | TYR9 |
| site_id | AD6 |
| Number of Residues | 27 |
| Details | binding site for residue APR D 201 |
| Chain | Residue |
| D | ASP22 |
| D | ILE23 |
| D | ALA38 |
| D | ASN40 |
| D | LYS44 |
| D | GLY46 |
| D | GLY47 |
| D | GLY48 |
| D | VAL49 |
| D | ALA50 |
| D | LEU126 |
| D | SER128 |
| D | ALA129 |
| D | GLY130 |
| D | ILE131 |
| D | PHE132 |
| D | ALA154 |
| D | PHE156 |
| D | EDO204 |
| D | HOH301 |
| D | HOH303 |
| D | HOH305 |
| D | HOH309 |
| D | HOH312 |
| D | HOH315 |
| D | HOH324 |
| D | HOH327 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue EDO D 202 |
| Chain | Residue |
| D | TYR68 |
| D | ASN72 |
| D | GLY73 |
| D | LEU75 |
| site_id | AD8 |
| Number of Residues | 5 |
| Details | binding site for residue EDO D 203 |
| Chain | Residue |
| A | GLN118 |
| A | EDO207 |
| D | GLY79 |
| D | SER80 |
| D | ASN115 |
| site_id | AD9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO D 204 |
| Chain | Residue |
| C | ASN58 |
| D | GLY47 |
| D | GLY48 |
| D | APR201 |
| site_id | AE1 |
| Number of Residues | 26 |
| Details | binding site for residue APR E 201 |
| Chain | Residue |
| E | ASP22 |
| E | ILE23 |
| E | ALA38 |
| E | ASN40 |
| E | LYS44 |
| E | GLY46 |
| E | GLY47 |
| E | GLY48 |
| E | VAL49 |
| E | ALA50 |
| E | LEU126 |
| E | SER128 |
| E | ALA129 |
| E | GLY130 |
| E | ILE131 |
| E | PHE132 |
| E | ALA154 |
| E | PHE156 |
| E | HOH306 |
| E | HOH313 |
| E | HOH314 |
| E | HOH320 |
| E | HOH321 |
| E | HOH322 |
| E | HOH328 |
| E | HOH329 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue MG E 202 |
| Chain | Residue |
| E | GLY0 |
| E | HIS1 |
| E | HIS91 |
| E | HOH301 |
| E | HOH307 |
| site_id | AE3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO E 203 |
| Chain | Residue |
| E | GLY8 |
| E | LYS19 |
| E | ASN20 |
| E | TYR161 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 169 |
| Details | Domain: {"description":"Macro 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00490","evidenceCode":"ECO:0000255"}]} |
