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6YAI

Clathrin with bound beta2 appendage of AP2

Functional Information from GO Data
ChainGOidnamespacecontents
A0000278biological_processmitotic cell cycle
A0005198molecular_functionstructural molecule activity
A0005819cellular_componentspindle
A0005905cellular_componentclathrin-coated pit
A0006886biological_processintracellular protein transport
A0006898biological_processreceptor-mediated endocytosis
A0016020cellular_componentmembrane
A0016192biological_processvesicle-mediated transport
A0030130cellular_componentclathrin coat of trans-Golgi network vesicle
A0030132cellular_componentclathrin coat of coated pit
A0030659cellular_componentcytoplasmic vesicle membrane
A0031410cellular_componentcytoplasmic vesicle
A0032051molecular_functionclathrin light chain binding
A0045334cellular_componentclathrin-coated endocytic vesicle
A0048268biological_processclathrin coat assembly
A0071439cellular_componentclathrin complex
B0000278biological_processmitotic cell cycle
B0005198molecular_functionstructural molecule activity
B0005819cellular_componentspindle
B0005905cellular_componentclathrin-coated pit
B0006886biological_processintracellular protein transport
B0006898biological_processreceptor-mediated endocytosis
B0016020cellular_componentmembrane
B0016192biological_processvesicle-mediated transport
B0030130cellular_componentclathrin coat of trans-Golgi network vesicle
B0030132cellular_componentclathrin coat of coated pit
B0030659cellular_componentcytoplasmic vesicle membrane
B0031410cellular_componentcytoplasmic vesicle
B0032051molecular_functionclathrin light chain binding
B0045334cellular_componentclathrin-coated endocytic vesicle
B0048268biological_processclathrin coat assembly
B0071439cellular_componentclathrin complex
C0000278biological_processmitotic cell cycle
C0005198molecular_functionstructural molecule activity
C0005819cellular_componentspindle
C0005905cellular_componentclathrin-coated pit
C0006886biological_processintracellular protein transport
C0006898biological_processreceptor-mediated endocytosis
C0016020cellular_componentmembrane
C0016192biological_processvesicle-mediated transport
C0030130cellular_componentclathrin coat of trans-Golgi network vesicle
C0030132cellular_componentclathrin coat of coated pit
C0030659cellular_componentcytoplasmic vesicle membrane
C0031410cellular_componentcytoplasmic vesicle
C0032051molecular_functionclathrin light chain binding
C0045334cellular_componentclathrin-coated endocytic vesicle
C0048268biological_processclathrin coat assembly
C0071439cellular_componentclathrin complex
D0005198molecular_functionstructural molecule activity
D0005802cellular_componenttrans-Golgi network
D0005829cellular_componentcytosol
D0005886cellular_componentplasma membrane
D0005905cellular_componentclathrin-coated pit
D0006886biological_processintracellular protein transport
D0016020cellular_componentmembrane
D0016192biological_processvesicle-mediated transport
D0030125cellular_componentclathrin vesicle coat
D0030130cellular_componentclathrin coat of trans-Golgi network vesicle
D0030132cellular_componentclathrin coat of coated pit
D0030659cellular_componentcytoplasmic vesicle membrane
D0030672cellular_componentsynaptic vesicle membrane
D0031410cellular_componentcytoplasmic vesicle
D0032050molecular_functionclathrin heavy chain binding
D0043231cellular_componentintracellular membrane-bounded organelle
D0060170cellular_componentciliary membrane
D0072583biological_processclathrin-dependent endocytosis
E0000278biological_processmitotic cell cycle
E0005198molecular_functionstructural molecule activity
E0005819cellular_componentspindle
E0005905cellular_componentclathrin-coated pit
E0006886biological_processintracellular protein transport
E0006898biological_processreceptor-mediated endocytosis
E0016020cellular_componentmembrane
E0016192biological_processvesicle-mediated transport
E0030130cellular_componentclathrin coat of trans-Golgi network vesicle
E0030132cellular_componentclathrin coat of coated pit
E0030659cellular_componentcytoplasmic vesicle membrane
E0031410cellular_componentcytoplasmic vesicle
E0032051molecular_functionclathrin light chain binding
E0045334cellular_componentclathrin-coated endocytic vesicle
E0048268biological_processclathrin coat assembly
E0071439cellular_componentclathrin complex
F0006886biological_processintracellular protein transport
F0016192biological_processvesicle-mediated transport
F0030117cellular_componentmembrane coat
F0030131cellular_componentclathrin adaptor complex
H0000278biological_processmitotic cell cycle
H0005198molecular_functionstructural molecule activity
H0005819cellular_componentspindle
H0005905cellular_componentclathrin-coated pit
H0006886biological_processintracellular protein transport
H0006898biological_processreceptor-mediated endocytosis
H0016020cellular_componentmembrane
H0016192biological_processvesicle-mediated transport
H0030130cellular_componentclathrin coat of trans-Golgi network vesicle
H0030132cellular_componentclathrin coat of coated pit
H0030659cellular_componentcytoplasmic vesicle membrane
H0031410cellular_componentcytoplasmic vesicle
H0032051molecular_functionclathrin light chain binding
H0045334cellular_componentclathrin-coated endocytic vesicle
H0048268biological_processclathrin coat assembly
H0071439cellular_componentclathrin complex
I0005198molecular_functionstructural molecule activity
I0005802cellular_componenttrans-Golgi network
I0005829cellular_componentcytosol
I0005886cellular_componentplasma membrane
I0005905cellular_componentclathrin-coated pit
I0006886biological_processintracellular protein transport
I0016020cellular_componentmembrane
I0016192biological_processvesicle-mediated transport
I0030125cellular_componentclathrin vesicle coat
I0030130cellular_componentclathrin coat of trans-Golgi network vesicle
I0030132cellular_componentclathrin coat of coated pit
I0030659cellular_componentcytoplasmic vesicle membrane
I0030672cellular_componentsynaptic vesicle membrane
I0031410cellular_componentcytoplasmic vesicle
I0032050molecular_functionclathrin heavy chain binding
I0043231cellular_componentintracellular membrane-bounded organelle
I0060170cellular_componentciliary membrane
I0072583biological_processclathrin-dependent endocytosis
J0000278biological_processmitotic cell cycle
J0005198molecular_functionstructural molecule activity
J0005819cellular_componentspindle
J0005905cellular_componentclathrin-coated pit
J0006886biological_processintracellular protein transport
J0006898biological_processreceptor-mediated endocytosis
J0016020cellular_componentmembrane
J0016192biological_processvesicle-mediated transport
J0030130cellular_componentclathrin coat of trans-Golgi network vesicle
J0030132cellular_componentclathrin coat of coated pit
J0030659cellular_componentcytoplasmic vesicle membrane
J0031410cellular_componentcytoplasmic vesicle
J0032051molecular_functionclathrin light chain binding
J0045334cellular_componentclathrin-coated endocytic vesicle
J0048268biological_processclathrin coat assembly
J0071439cellular_componentclathrin complex
K0000278biological_processmitotic cell cycle
K0005198molecular_functionstructural molecule activity
K0005819cellular_componentspindle
K0005905cellular_componentclathrin-coated pit
K0006886biological_processintracellular protein transport
K0006898biological_processreceptor-mediated endocytosis
K0016020cellular_componentmembrane
K0016192biological_processvesicle-mediated transport
K0030130cellular_componentclathrin coat of trans-Golgi network vesicle
K0030132cellular_componentclathrin coat of coated pit
K0030659cellular_componentcytoplasmic vesicle membrane
K0031410cellular_componentcytoplasmic vesicle
K0032051molecular_functionclathrin light chain binding
K0045334cellular_componentclathrin-coated endocytic vesicle
K0048268biological_processclathrin coat assembly
K0071439cellular_componentclathrin complex
L0000278biological_processmitotic cell cycle
L0005198molecular_functionstructural molecule activity
L0005819cellular_componentspindle
L0005905cellular_componentclathrin-coated pit
L0006886biological_processintracellular protein transport
L0006898biological_processreceptor-mediated endocytosis
L0016020cellular_componentmembrane
L0016192biological_processvesicle-mediated transport
L0030130cellular_componentclathrin coat of trans-Golgi network vesicle
L0030132cellular_componentclathrin coat of coated pit
L0030659cellular_componentcytoplasmic vesicle membrane
L0031410cellular_componentcytoplasmic vesicle
L0032051molecular_functionclathrin light chain binding
L0045334cellular_componentclathrin-coated endocytic vesicle
L0048268biological_processclathrin coat assembly
L0071439cellular_componentclathrin complex
M0000278biological_processmitotic cell cycle
M0005198molecular_functionstructural molecule activity
M0005819cellular_componentspindle
M0005905cellular_componentclathrin-coated pit
M0006886biological_processintracellular protein transport
M0006898biological_processreceptor-mediated endocytosis
M0016020cellular_componentmembrane
M0016192biological_processvesicle-mediated transport
M0030130cellular_componentclathrin coat of trans-Golgi network vesicle
M0030132cellular_componentclathrin coat of coated pit
M0030659cellular_componentcytoplasmic vesicle membrane
M0031410cellular_componentcytoplasmic vesicle
M0032051molecular_functionclathrin light chain binding
M0045334cellular_componentclathrin-coated endocytic vesicle
M0048268biological_processclathrin coat assembly
M0071439cellular_componentclathrin complex
N0005198molecular_functionstructural molecule activity
N0005802cellular_componenttrans-Golgi network
N0005829cellular_componentcytosol
N0005886cellular_componentplasma membrane
N0005905cellular_componentclathrin-coated pit
N0006886biological_processintracellular protein transport
N0016020cellular_componentmembrane
N0016192biological_processvesicle-mediated transport
N0030125cellular_componentclathrin vesicle coat
N0030130cellular_componentclathrin coat of trans-Golgi network vesicle
N0030132cellular_componentclathrin coat of coated pit
N0030659cellular_componentcytoplasmic vesicle membrane
N0030672cellular_componentsynaptic vesicle membrane
N0031410cellular_componentcytoplasmic vesicle
N0032050molecular_functionclathrin heavy chain binding
N0043231cellular_componentintracellular membrane-bounded organelle
N0060170cellular_componentciliary membrane
N0072583biological_processclathrin-dependent endocytosis
O0005198molecular_functionstructural molecule activity
O0005802cellular_componenttrans-Golgi network
O0005829cellular_componentcytosol
O0005886cellular_componentplasma membrane
O0005905cellular_componentclathrin-coated pit
O0006886biological_processintracellular protein transport
O0016020cellular_componentmembrane
O0016192biological_processvesicle-mediated transport
O0030125cellular_componentclathrin vesicle coat
O0030130cellular_componentclathrin coat of trans-Golgi network vesicle
O0030132cellular_componentclathrin coat of coated pit
O0030659cellular_componentcytoplasmic vesicle membrane
O0030672cellular_componentsynaptic vesicle membrane
O0031410cellular_componentcytoplasmic vesicle
O0032050molecular_functionclathrin heavy chain binding
O0043231cellular_componentintracellular membrane-bounded organelle
O0060170cellular_componentciliary membrane
O0072583biological_processclathrin-dependent endocytosis
Functional Information from PROSITE/UniProt
site_idPS00224
Number of Residues7
DetailsCLATHRIN_LIGHT_CHN_1 Clathrin light chain signature 1. FLAQQES
ChainResidueDetails
DPHE27-SER33

site_idPS00581
Number of Residues14
DetailsCLATHRIN_LIGHT_CHN_2 Clathrin light chain signature 2. KDvSRLRsVLMsLK
ChainResidueDetails
DLYS210-LYS223

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI3
Number of Residues96
DetailsRegion: {"description":"Interaction with ARRB1"}
ChainResidueDetails

site_idSWS_FT_FI4
Number of Residues1
DetailsModified residue: {"description":"Phosphotyrosine; by SRC","evidences":[{"source":"PubMed","id":"17456551","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18938240","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI5
Number of Residues1
DetailsModified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P62944","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

238582

PDB entries from 2025-07-09

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