6Y3Z

Crystal structure of the Pby1 ATP-grasp enzyme bound to the S. cerevisiae mRNA decapping complex (Dcp1-Dcp2-Edc3)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000184	biological_process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
A	0000290	biological_process	deadenylation-dependent decapping of nuclear-transcribed mRNA
A	0003723	molecular_function	RNA binding
A	0016787	molecular_function	hydrolase activity
A	0030145	molecular_function	manganese ion binding
A	0140933	molecular_function	5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity
B	0000184	biological_process	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
B	0000290	biological_process	deadenylation-dependent decapping of nuclear-transcribed mRNA
B	0000932	cellular_component	P-body
B	0003723	molecular_function	RNA binding
B	0003729	molecular_function	mRNA binding
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0006397	biological_process	mRNA processing
B	0008047	molecular_function	enzyme activator activity
B	0031087	biological_process	deadenylation-independent decapping of nuclear-transcribed mRNA
B	0043085	biological_process	positive regulation of catalytic activity
B	0098562	cellular_component	cytoplasmic side of membrane
B	0098745	cellular_component	RNA decapping complex
C	0003723	molecular_function	RNA binding
P	0005524	molecular_function	ATP binding
P	0036211	biological_process	protein modification process

Functional Information from PDB Data

Functional Information from PROSITE/UniProt

site_id	PS00893
Number of Residues	22
Details	NUDIX_BOX Nudix box signature. GkiskdEndidCCiREVkEEiG

Chain	Residue	Details
A	GLY134-GLY155

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"18407956","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details