Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0002218 | biological_process | activation of innate immune response |
| A | 0032481 | biological_process | positive regulation of type I interferon production |
| B | 0002218 | biological_process | activation of innate immune response |
| B | 0032481 | biological_process | positive regulation of type I interferon production |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | binding site for residue V67 A 401 |
| Chain | Residue |
| A | SER161 |
| A | HOH520 |
| B | ILE234 |
| B | ARG237 |
| B | THR262 |
| B | PRO263 |
| B | V67401 |
| A | TYR162 |
| A | GLY165 |
| A | TYR166 |
| A | ARG237 |
| A | SER240 |
| A | THR262 |
| A | HOH502 |
| A | HOH511 |
| site_id | AC2 |
| Number of Residues | 16 |
| Details | binding site for residue V67 B 401 |
| Chain | Residue |
| A | ARG237 |
| A | THR262 |
| A | PRO263 |
| A | V67401 |
| B | SER161 |
| B | TYR162 |
| B | GLY165 |
| B | TYR166 |
| B | ARG237 |
| B | TYR239 |
| B | SER240 |
| B | GLU259 |
| B | THR262 |
| B | HOH503 |
| B | HOH506 |
| B | HOH523 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"23519410","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4KBY","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"23910378","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4LOK","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q86WV6","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"UniProtKB","id":"Q86WV6","evidenceCode":"ECO:0000250"}]} |
