6XNN
Crystal Structure of Mouse STING CTD complex with SR-717.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B (A, B) | Stimulator of interferon genes protein | polymer | 187 | 21458.4 | 2 | UniProt (Q3TBT3) Pfam (PF15009) | Mus musculus (Mouse) | mSTING,Endoplasmic reticulum interferon stimulator,ERIS,Mediator of IRF3 activation,MMITA,Transmembrane protein 173 |
2 | C, D (A, B) | 4,5-difluoro-2-{[6-(1H-imidazol-1-yl)pyridazine-3-carbonyl]amino}benzoic acid | non-polymer | 345.3 | 2 | Chemie (V67) | |||
3 | E, F (A, B) | water | water | 18.0 | 129 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 42916.8 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 690.5 | |
All* | Total formula weight | 43607.3 |