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6WZW

Ash1L SET domain in complex with AS-85

Functional Information from GO Data
ChainGOidnamespacecontents
A0005634cellular_componentnucleus
A0042054molecular_functionhistone methyltransferase activity
Functional Information from PDB Data
site_idAC1
Number of Residues7
Detailsbinding site for residue EPE A 2301
ChainResidue
AGLU2263
ALYS2264
AGLN2265
ALYS2269
AGLU2273
AUG72306
AHOH2449

site_idAC2
Number of Residues19
Detailsbinding site for residue SAM A 2302
ChainResidue
ASER2191
AASP2192
AHIS2193
ATYR2194
AARG2214
APHE2215
AASN2217
AHIS2218
ATYR2255
AGLN2266
ALEU2267
ACYS2268
ALYS2269
AILE2279
AHOH2431
AHOH2433
AHOH2514
ALYS2150
ATRP2152

site_idAC3
Number of Residues4
Detailsbinding site for residue ZN A 2303
ChainResidue
ACYS2091
ACYS2093
ACYS2104
ACYS2108

site_idAC4
Number of Residues4
Detailsbinding site for residue ZN A 2304
ChainResidue
ACYS2104
ACYS2117
ACYS2122
ACYS2128

site_idAC5
Number of Residues4
Detailsbinding site for residue ZN A 2305
ChainResidue
ACYS2220
ACYS2268
ACYS2270
ACYS2275

site_idAC6
Number of Residues22
Detailsbinding site for residue UG7 A 2306
ChainResidue
AALA2064
AHIS2193
ATYR2194
ACYS2195
ATYR2255
AASN2256
ASER2259
APHE2260
AASN2261
AVAL2262
ALYS2264
AGLN2265
AGLN2266
ACYS2275
AARG2276
AGLY2277
AILE2278
AILE2279
AGLY2280
AEPE2301
AHOH2412
AHOH2529

229183

PDB entries from 2024-12-18

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