Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004725 | molecular_function | protein tyrosine phosphatase activity |
A | 0006470 | biological_process | protein dephosphorylation |
A | 0016311 | biological_process | dephosphorylation |
B | 0004725 | molecular_function | protein tyrosine phosphatase activity |
B | 0006470 | biological_process | protein dephosphorylation |
B | 0016311 | biological_process | dephosphorylation |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 14 |
Details | binding site for residue U9Y A 601 |
Chain | Residue |
A | THR108 |
A | GLN257 |
A | PRO491 |
A | LYS492 |
A | GLN495 |
A | HOH758 |
A | GLU110 |
A | ARG111 |
A | PHE113 |
A | THR218 |
A | THR219 |
A | GLU249 |
A | GLU250 |
A | THR253 |
site_id | AC2 |
Number of Residues | 14 |
Details | binding site for residue U9Y B 601 |
Chain | Residue |
B | THR108 |
B | GLU110 |
B | ARG111 |
B | PHE113 |
B | THR218 |
B | THR219 |
B | GLU249 |
B | GLU250 |
B | THR253 |
B | LEU254 |
B | GLN257 |
B | PRO491 |
B | LYS492 |
B | GLN495 |
Functional Information from PROSITE/UniProt
site_id | PS00383 |
Number of Residues | 11 |
Details | TYR_PHOSPHATASE_1 Tyrosine specific protein phosphatases active site. VHCsaGigRTG |
Chain | Residue | Details |
A | VAL457-GLY467 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | ACT_SITE: Phosphocysteine intermediate |
Chain | Residue | Details |
A | CYS459 | |
B | CYS459 | |
site_id | SWS_FT_FI2 |
Number of Residues | 6 |
Details | BINDING: BINDING => ECO:0000250 |
Chain | Residue | Details |
A | ASP425 | |
A | CYS459 | |
A | GLN506 | |
B | ASP425 | |
B | CYS459 | |
B | GLN506 | |
Chain | Residue | Details |
A | THR2 | |
B | THR2 | |
Chain | Residue | Details |
A | TYR62 | |
B | TYR62 | |
Chain | Residue | Details |
A | TYR66 | |
B | TYR66 | |