6W9A
RNF12 RING domain in complex with Ube2e2
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 301 |
| Chain | Residue |
| A | PRO71 |
| A | PRO72 |
| A | PRO73 |
| A | ASN74 |
| A | SER134 |
| A | GLN135 |
| C | THR68 |
| C | LEU69 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 701 |
| Chain | Residue |
| B | CYS573 |
| B | HIS593 |
| B | CYS596 |
| B | CYS570 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 702 |
| Chain | Residue |
| B | CYS588 |
| B | HIS590 |
| B | CYS607 |
| B | CYS610 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue GOL C 301 |
| Chain | Residue |
| C | PRO119 |
| C | LYS120 |
| C | VAL121 |
| C | THR122 |
| C | VAL137 |
| C | ILE138 |
| C | LEU143 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue ZN D 701 |
| Chain | Residue |
| D | CYS570 |
| D | CYS573 |
| D | HIS593 |
| D | CYS596 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue ZN D 702 |
| Chain | Residue |
| D | CYS588 |
| D | HIS590 |
| D | CYS607 |
| D | CYS610 |
Functional Information from PROSITE/UniProt
| site_id | PS00183 |
| Number of Residues | 16 |
| Details | UBC_1 Ubiquitin-conjugating (UBC) active site signature. YHCNInsq.GvICLdiL |
| Chain | Residue | Details |
| A | TYR128-LEU143 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 292 |
| Details | Domain: {"description":"UBC core","evidences":[{"source":"PROSITE-ProRule","id":"PRU00388","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Glycyl thioester intermediate","evidences":[{"source":"PROSITE-ProRule","id":"PRU00388","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10133","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 82 |
| Details | Zinc finger: {"description":"RING-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00175","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
