Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016571 | biological_process | histone methylation |
| A | 0035098 | cellular_component | ESC/E(Z) complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | binding site for residue Q3A A 501 |
| Chain | Residue |
| A | PHE97 |
| A | ARG414 |
| A | HOH751 |
| A | TYR148 |
| A | ASN194 |
| A | LYS211 |
| A | LEU240 |
| A | ASP310 |
| A | TYR365 |
| A | MET366 |
| A | ARG367 |
| site_id | AC2 |
| Number of Residues | 16 |
| Details | binding site for residue Q3A A 502 |
| Chain | Residue |
| A | HIS199 |
| A | ARG201 |
| A | ASP202 |
| A | LEU205 |
| A | LEU247 |
| A | GLY248 |
| A | ILE265 |
| A | MET271 |
| A | ILE274 |
| A | LYS275 |
| A | TYR278 |
| A | Q3A503 |
| A | HOH740 |
| A | HOH744 |
| A | HOH773 |
| A | HOH786 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | binding site for residue Q3A A 503 |
| Chain | Residue |
| A | ARG201 |
| A | ASP212 |
| A | ALA214 |
| A | ILE228 |
| A | GLY230 |
| A | GLY231 |
| A | VAL232 |
| A | LYS293 |
| A | Q3A502 |
| A | HOH754 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue NA A 504 |
| Chain | Residue |
| A | CYS182 |
| A | HIS185 |
| A | HOH906 |
| A | HOH921 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue FMT A 505 |
| Chain | Residue |
| A | LYS184 |
| A | ILE220 |
| A | HOH624 |
| A | HOH657 |
Functional Information from PROSITE/UniProt
| site_id | PS00678 |
| Number of Residues | 15 |
| Details | WD_REPEATS_1 Trp-Asp (WD) repeats signature. LLSVskDhALRLWNI |
| Chain | Residue | Details |
| A | LEU206-ILE220 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | LYS197 | |
| A | LYS268 | |
| A | LYS284 | |
