6W6L

Cryo-EM structure of the human ribosome-TMCO1 translocon

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
1	0005048	molecular_function	signal sequence binding
1	0005262	molecular_function	calcium channel activity
1	0005515	molecular_function	protein binding
1	0005783	cellular_component	endoplasmic reticulum
1	0005784	cellular_component	Sec61 translocon complex
1	0005789	cellular_component	endoplasmic reticulum membrane
1	0006613	biological_process	cotranslational protein targeting to membrane
1	0006614	biological_process	SRP-dependent cotranslational protein targeting to membrane
1	0006616	biological_process	SRP-dependent cotranslational protein targeting to membrane, translocation
1	0006620	biological_process	post-translational protein targeting to endoplasmic reticulum membrane
1	0007029	biological_process	endoplasmic reticulum organization
1	0008320	molecular_function	protein transmembrane transporter activity
1	0015031	biological_process	protein transport
1	0016020	cellular_component	membrane
1	0031204	biological_process	post-translational protein targeting to membrane, translocation
1	0039019	biological_process	pronephric nephron development
1	0043022	molecular_function	ribosome binding
1	0045047	biological_process	protein targeting to ER
1	0045048	biological_process	protein insertion into ER membrane
1	0070588	biological_process	calcium ion transmembrane transport
2	0005515	molecular_function	protein binding
2	0005783	cellular_component	endoplasmic reticulum
2	0005789	cellular_component	endoplasmic reticulum membrane
2	0005829	cellular_component	cytosol
2	0006605	biological_process	protein targeting
2	0006886	biological_process	intracellular protein transport
2	0008320	molecular_function	protein transmembrane transporter activity
2	0015031	biological_process	protein transport
2	0016020	cellular_component	membrane
2	0031204	biological_process	post-translational protein targeting to membrane, translocation
2	0043022	molecular_function	ribosome binding
2	0045047	biological_process	protein targeting to ER
2	0071261	cellular_component	Ssh1 translocon complex
3	0003723	molecular_function	RNA binding
3	0005085	molecular_function	guanyl-nucleotide exchange factor activity
3	0005515	molecular_function	protein binding
3	0005783	cellular_component	endoplasmic reticulum
3	0005784	cellular_component	Sec61 translocon complex
3	0005789	cellular_component	endoplasmic reticulum membrane
3	0005829	cellular_component	cytosol
3	0006616	biological_process	SRP-dependent cotranslational protein targeting to membrane, translocation
3	0006886	biological_process	intracellular protein transport
3	0015031	biological_process	protein transport
3	0016020	cellular_component	membrane
3	0030970	biological_process	retrograde protein transport, ER to cytosol
3	0031204	biological_process	post-translational protein targeting to membrane, translocation
3	0031205	cellular_component	endoplasmic reticulum Sec complex
3	0036503	biological_process	ERAD pathway
3	0043022	molecular_function	ribosome binding
3	0044322	cellular_component	endoplasmic reticulum quality control compartment
3	0048408	molecular_function	epidermal growth factor binding
4	0005515	molecular_function	protein binding
4	0005634	cellular_component	nucleus
4	0005783	cellular_component	endoplasmic reticulum
4	0005789	cellular_component	endoplasmic reticulum membrane
4	0005886	cellular_component	plasma membrane
4	0031965	cellular_component	nuclear membrane
4	0032991	cellular_component	protein-containing complex
4	0036228	biological_process	protein localization to nuclear inner membrane
4	0043022	molecular_function	ribosome binding
4	0160063	biological_process	multi-pass transmembrane protein insertion into ER membrane
4	0160064	cellular_component	multi-pass translocon complex
5	0009966	biological_process	regulation of signal transduction
5	0016020	cellular_component	membrane
6	0005262	molecular_function	calcium channel activity
6	0005789	cellular_component	endoplasmic reticulum membrane
6	0016020	cellular_component	membrane
6	0032469	biological_process	endoplasmic reticulum calcium ion homeostasis
7	0005509	molecular_function	calcium ion binding
7	0005783	cellular_component	endoplasmic reticulum
7	0032469	biological_process	endoplasmic reticulum calcium ion homeostasis
a	0002181	biological_process	cytoplasmic translation
a	0003723	molecular_function	RNA binding
a	0003735	molecular_function	structural constituent of ribosome
a	0005515	molecular_function	protein binding
a	0005634	cellular_component	nucleus
a	0005654	cellular_component	nucleoplasm
a	0005730	cellular_component	nucleolus
a	0005737	cellular_component	cytoplasm
a	0005783	cellular_component	endoplasmic reticulum
a	0005791	cellular_component	rough endoplasmic reticulum
a	0005829	cellular_component	cytosol
a	0005840	cellular_component	ribosome
a	0005925	cellular_component	focal adhesion
a	0006364	biological_process	rRNA processing
a	0006412	biological_process	translation
a	0016020	cellular_component	membrane
a	0022625	cellular_component	cytosolic large ribosomal subunit
a	0022626	cellular_component	cytosolic ribosome
a	0045202	cellular_component	synapse
a	0070062	cellular_component	extracellular exosome
a	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
a	1904044	biological_process	response to aldosterone
a	1990904	cellular_component	ribonucleoprotein complex
A	0002181	biological_process	cytoplasmic translation
A	0003723	molecular_function	RNA binding
A	0003735	molecular_function	structural constituent of ribosome
A	0005515	molecular_function	protein binding
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005840	cellular_component	ribosome
A	0005925	cellular_component	focal adhesion
A	0006412	biological_process	translation
A	0014069	cellular_component	postsynaptic density
A	0015934	cellular_component	large ribosomal subunit
A	0016020	cellular_component	membrane
A	0019843	molecular_function	rRNA binding
A	0022625	cellular_component	cytosolic large ribosomal subunit
A	0022626	cellular_component	cytosolic ribosome
A	0045202	cellular_component	synapse
A	0098794	cellular_component	postsynapse
A	1990904	cellular_component	ribonucleoprotein complex
b	0002181	biological_process	cytoplasmic translation
b	0003723	molecular_function	RNA binding
b	0003735	molecular_function	structural constituent of ribosome
b	0005515	molecular_function	protein binding
b	0005654	cellular_component	nucleoplasm
b	0005737	cellular_component	cytoplasm
b	0005783	cellular_component	endoplasmic reticulum
b	0005829	cellular_component	cytosol
b	0005840	cellular_component	ribosome
b	0006412	biological_process	translation
b	0015934	cellular_component	large ribosomal subunit
b	0016020	cellular_component	membrane
b	0022625	cellular_component	cytosolic large ribosomal subunit
b	0022626	cellular_component	cytosolic ribosome
b	1990904	cellular_component	ribonucleoprotein complex
B	0002181	biological_process	cytoplasmic translation
B	0003723	molecular_function	RNA binding
B	0003735	molecular_function	structural constituent of ribosome
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005730	cellular_component	nucleolus
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005840	cellular_component	ribosome
B	0005925	cellular_component	focal adhesion
B	0006412	biological_process	translation
B	0022625	cellular_component	cytosolic large ribosomal subunit
B	0022626	cellular_component	cytosolic ribosome
B	0032991	cellular_component	protein-containing complex
B	0070062	cellular_component	extracellular exosome
B	0071353	biological_process	cellular response to interleukin-4
B	1990904	cellular_component	ribonucleoprotein complex
c	0002181	biological_process	cytoplasmic translation
c	0003723	molecular_function	RNA binding
c	0003735	molecular_function	structural constituent of ribosome
c	0005737	cellular_component	cytoplasm
c	0005829	cellular_component	cytosol
c	0005840	cellular_component	ribosome
c	0006412	biological_process	translation
c	0007566	biological_process	embryo implantation
c	0008201	molecular_function	heparin binding
c	0016020	cellular_component	membrane
c	0022625	cellular_component	cytosolic large ribosomal subunit
c	0022626	cellular_component	cytosolic ribosome
c	0045296	molecular_function	cadherin binding
c	1990904	cellular_component	ribonucleoprotein complex
C	0002181	biological_process	cytoplasmic translation
C	0003723	molecular_function	RNA binding
C	0003735	molecular_function	structural constituent of ribosome
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005730	cellular_component	nucleolus
C	0005737	cellular_component	cytoplasm
C	0005791	cellular_component	rough endoplasmic reticulum
C	0005829	cellular_component	cytosol
C	0005840	cellular_component	ribosome
C	0005925	cellular_component	focal adhesion
C	0006412	biological_process	translation
C	0016020	cellular_component	membrane
C	0022625	cellular_component	cytosolic large ribosomal subunit
C	0022626	cellular_component	cytosolic ribosome
C	0070062	cellular_component	extracellular exosome
C	1990904	cellular_component	ribonucleoprotein complex
d	0002181	biological_process	cytoplasmic translation
d	0003723	molecular_function	RNA binding
d	0003735	molecular_function	structural constituent of ribosome
d	0005515	molecular_function	protein binding
d	0005634	cellular_component	nucleus
d	0005737	cellular_component	cytoplasm
d	0005829	cellular_component	cytosol
d	0005840	cellular_component	ribosome
d	0005925	cellular_component	focal adhesion
d	0006412	biological_process	translation
d	0014069	cellular_component	postsynaptic density
d	0016020	cellular_component	membrane
d	0022625	cellular_component	cytosolic large ribosomal subunit
d	0022626	cellular_component	cytosolic ribosome
d	0031640	biological_process	killing of cells of another organism
d	0045202	cellular_component	synapse
d	0050829	biological_process	defense response to Gram-negative bacterium
d	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
d	0070062	cellular_component	extracellular exosome
d	1990904	cellular_component	ribonucleoprotein complex
e	0003735	molecular_function	structural constituent of ribosome
e	0005840	cellular_component	ribosome
e	0006412	biological_process	translation
f	0002181	biological_process	cytoplasmic translation
f	0003723	molecular_function	RNA binding
f	0003735	molecular_function	structural constituent of ribosome
f	0005737	cellular_component	cytoplasm
f	0005829	cellular_component	cytosol
f	0005840	cellular_component	ribosome
f	0006412	biological_process	translation
f	0016020	cellular_component	membrane
f	0022625	cellular_component	cytosolic large ribosomal subunit
f	0022626	cellular_component	cytosolic ribosome
f	1990904	cellular_component	ribonucleoprotein complex
F	0000027	biological_process	ribosomal large subunit assembly
F	0002181	biological_process	cytoplasmic translation
F	0003723	molecular_function	RNA binding
F	0003730	molecular_function	mRNA 3'-UTR binding
F	0003735	molecular_function	structural constituent of ribosome
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005654	cellular_component	nucleoplasm
F	0005730	cellular_component	nucleolus
F	0005737	cellular_component	cytoplasm
F	0005783	cellular_component	endoplasmic reticulum
F	0005829	cellular_component	cytosol
F	0005840	cellular_component	ribosome
F	0005925	cellular_component	focal adhesion
F	0006364	biological_process	rRNA processing
F	0006412	biological_process	translation
F	0008097	molecular_function	5S rRNA binding
F	0010628	biological_process	positive regulation of gene expression
F	0016020	cellular_component	membrane
F	0019843	molecular_function	rRNA binding
F	0022625	cellular_component	cytosolic large ribosomal subunit
F	0022626	cellular_component	cytosolic ribosome
F	0031625	molecular_function	ubiquitin protein ligase binding
F	0032991	cellular_component	protein-containing complex
F	0042273	biological_process	ribosomal large subunit biogenesis
F	0045727	biological_process	positive regulation of translation
F	0048027	molecular_function	mRNA 5'-UTR binding
F	0050821	biological_process	protein stabilization
F	0070062	cellular_component	extracellular exosome
F	1901796	biological_process	regulation of signal transduction by p53 class mediator
F	1904667	biological_process	negative regulation of ubiquitin protein ligase activity
F	1990904	cellular_component	ribonucleoprotein complex
F	1990948	molecular_function	ubiquitin ligase inhibitor activity
F	2000059	biological_process	negative regulation of ubiquitin-dependent protein catabolic process
F	2000435	biological_process	negative regulation of protein neddylation
g	0000049	molecular_function	tRNA binding
g	0002181	biological_process	cytoplasmic translation
g	0003723	molecular_function	RNA binding
g	0003735	molecular_function	structural constituent of ribosome
g	0005515	molecular_function	protein binding
g	0005737	cellular_component	cytoplasm
g	0005829	cellular_component	cytosol
g	0005840	cellular_component	ribosome
g	0006364	biological_process	rRNA processing
g	0006412	biological_process	translation
g	0016020	cellular_component	membrane
g	0022625	cellular_component	cytosolic large ribosomal subunit
g	0022626	cellular_component	cytosolic ribosome
g	0042273	biological_process	ribosomal large subunit biogenesis
g	0070062	cellular_component	extracellular exosome
g	1990904	cellular_component	ribonucleoprotein complex
G	0000027	biological_process	ribosomal large subunit assembly
G	0002181	biological_process	cytoplasmic translation
G	0003677	molecular_function	DNA binding
G	0003723	molecular_function	RNA binding
G	0003735	molecular_function	structural constituent of ribosome
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005737	cellular_component	cytoplasm
G	0005783	cellular_component	endoplasmic reticulum
G	0005791	cellular_component	rough endoplasmic reticulum
G	0005829	cellular_component	cytosol
G	0005840	cellular_component	ribosome
G	0005925	cellular_component	focal adhesion
G	0006355	biological_process	regulation of DNA-templated transcription
G	0006412	biological_process	translation
G	0014069	cellular_component	postsynaptic density
G	0016020	cellular_component	membrane
G	0022625	cellular_component	cytosolic large ribosomal subunit
G	0022626	cellular_component	cytosolic ribosome
G	0036464	cellular_component	cytoplasmic ribonucleoprotein granule
G	0045202	cellular_component	synapse
G	0045296	molecular_function	cadherin binding
G	1990904	cellular_component	ribonucleoprotein complex
h	0002181	biological_process	cytoplasmic translation
h	0003723	molecular_function	RNA binding
h	0003735	molecular_function	structural constituent of ribosome
h	0005515	molecular_function	protein binding
h	0005730	cellular_component	nucleolus
h	0005737	cellular_component	cytoplasm
h	0005783	cellular_component	endoplasmic reticulum
h	0005829	cellular_component	cytosol
h	0005840	cellular_component	ribosome
h	0006412	biological_process	translation
h	0022625	cellular_component	cytosolic large ribosomal subunit
h	0022626	cellular_component	cytosolic ribosome
h	0045202	cellular_component	synapse
h	0045296	molecular_function	cadherin binding
h	0070062	cellular_component	extracellular exosome
h	1990904	cellular_component	ribonucleoprotein complex
H	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H	0002181	biological_process	cytoplasmic translation
H	0003677	molecular_function	DNA binding
H	0003723	molecular_function	RNA binding
H	0003729	molecular_function	mRNA binding
H	0003735	molecular_function	structural constituent of ribosome
H	0005515	molecular_function	protein binding
H	0005634	cellular_component	nucleus
H	0005730	cellular_component	nucleolus
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0005840	cellular_component	ribosome
H	0005925	cellular_component	focal adhesion
H	0006364	biological_process	rRNA processing
H	0006412	biological_process	translation
H	0014069	cellular_component	postsynaptic density
H	0016020	cellular_component	membrane
H	0022625	cellular_component	cytosolic large ribosomal subunit
H	0022626	cellular_component	cytosolic ribosome
H	0042273	biological_process	ribosomal large subunit biogenesis
H	0042802	molecular_function	identical protein binding
H	1990904	cellular_component	ribonucleoprotein complex
i	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
i	0002181	biological_process	cytoplasmic translation
i	0003723	molecular_function	RNA binding
i	0003729	molecular_function	mRNA binding
i	0003735	molecular_function	structural constituent of ribosome
i	0005730	cellular_component	nucleolus
i	0005737	cellular_component	cytoplasm
i	0005829	cellular_component	cytosol
i	0005840	cellular_component	ribosome
i	0006412	biological_process	translation
i	0016020	cellular_component	membrane
i	0022625	cellular_component	cytosolic large ribosomal subunit
i	0022626	cellular_component	cytosolic ribosome
i	1990904	cellular_component	ribonucleoprotein complex
I	0000470	biological_process	maturation of LSU-rRNA
I	0002181	biological_process	cytoplasmic translation
I	0003723	molecular_function	RNA binding
I	0003735	molecular_function	structural constituent of ribosome
I	0005515	molecular_function	protein binding
I	0005634	cellular_component	nucleus
I	0005730	cellular_component	nucleolus
I	0005737	cellular_component	cytoplasm
I	0005829	cellular_component	cytosol
I	0005840	cellular_component	ribosome
I	0005925	cellular_component	focal adhesion
I	0006412	biological_process	translation
I	0016020	cellular_component	membrane
I	0022625	cellular_component	cytosolic large ribosomal subunit
I	0022626	cellular_component	cytosolic ribosome
I	0042254	biological_process	ribosome biogenesis
I	0045202	cellular_component	synapse
I	0045296	molecular_function	cadherin binding
I	1990904	cellular_component	ribonucleoprotein complex
j	0002181	biological_process	cytoplasmic translation
j	0003723	molecular_function	RNA binding
j	0003735	molecular_function	structural constituent of ribosome
j	0005515	molecular_function	protein binding
j	0005730	cellular_component	nucleolus
j	0005737	cellular_component	cytoplasm
j	0005829	cellular_component	cytosol
j	0005840	cellular_component	ribosome
j	0006412	biological_process	translation
j	0016020	cellular_component	membrane
j	0022625	cellular_component	cytosolic large ribosomal subunit
j	0022626	cellular_component	cytosolic ribosome
j	0045202	cellular_component	synapse
j	1990904	cellular_component	ribonucleoprotein complex
J	0002181	biological_process	cytoplasmic translation
J	0003723	molecular_function	RNA binding
J	0003735	molecular_function	structural constituent of ribosome
J	0005515	molecular_function	protein binding
J	0005634	cellular_component	nucleus
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0005840	cellular_component	ribosome
J	0005925	cellular_component	focal adhesion
J	0006412	biological_process	translation
J	0016020	cellular_component	membrane
J	0019843	molecular_function	rRNA binding
J	0022625	cellular_component	cytosolic large ribosomal subunit
J	0022626	cellular_component	cytosolic ribosome
J	1990904	cellular_component	ribonucleoprotein complex
k	0002181	biological_process	cytoplasmic translation
k	0003723	molecular_function	RNA binding
k	0003735	molecular_function	structural constituent of ribosome
k	0005737	cellular_component	cytoplasm
k	0005829	cellular_component	cytosol
k	0005840	cellular_component	ribosome
k	0006412	biological_process	translation
k	0019843	molecular_function	rRNA binding
k	0022625	cellular_component	cytosolic large ribosomal subunit
k	0022626	cellular_component	cytosolic ribosome
k	0046872	molecular_function	metal ion binding
k	0097371	molecular_function	MDM2/MDM4 family protein binding
k	1901798	biological_process	positive regulation of signal transduction by p53 class mediator
k	1990904	cellular_component	ribonucleoprotein complex
k	1990948	molecular_function	ubiquitin ligase inhibitor activity
K	0000027	biological_process	ribosomal large subunit assembly
K	0000122	biological_process	negative regulation of transcription by RNA polymerase II
K	0002181	biological_process	cytoplasmic translation
K	0003723	molecular_function	RNA binding
K	0003735	molecular_function	structural constituent of ribosome
K	0005515	molecular_function	protein binding
K	0005634	cellular_component	nucleus
K	0005737	cellular_component	cytoplasm
K	0005783	cellular_component	endoplasmic reticulum
K	0005790	cellular_component	smooth endoplasmic reticulum
K	0005829	cellular_component	cytosol
K	0005840	cellular_component	ribosome
K	0006412	biological_process	translation
K	0006417	biological_process	regulation of translation
K	0016020	cellular_component	membrane
K	0022625	cellular_component	cytosolic large ribosomal subunit
K	0022626	cellular_component	cytosolic ribosome
K	0032991	cellular_component	protein-containing complex
K	0043066	biological_process	negative regulation of apoptotic process
K	0045182	molecular_function	translation regulator activity
K	1990403	biological_process	embryonic brain development
K	1990904	cellular_component	ribonucleoprotein complex
l	0001501	biological_process	skeletal system development
l	0001503	biological_process	ossification
l	0002181	biological_process	cytoplasmic translation
l	0003723	molecular_function	RNA binding
l	0003735	molecular_function	structural constituent of ribosome
l	0005515	molecular_function	protein binding
l	0005737	cellular_component	cytoplasm
l	0005829	cellular_component	cytosol
l	0005840	cellular_component	ribosome
l	0005925	cellular_component	focal adhesion
l	0006412	biological_process	translation
l	0006417	biological_process	regulation of translation
l	0007605	biological_process	sensory perception of sound
l	0014069	cellular_component	postsynaptic density
l	0022618	biological_process	protein-RNA complex assembly
l	0022625	cellular_component	cytosolic large ribosomal subunit
l	0022626	cellular_component	cytosolic ribosome
l	0033291	cellular_component	eukaryotic 80S initiation complex
l	0034463	biological_process	90S preribosome assembly
l	0042474	biological_process	middle ear morphogenesis
l	0045202	cellular_component	synapse
l	0048318	biological_process	axial mesoderm development
l	1990904	cellular_component	ribonucleoprotein complex
L	0000027	biological_process	ribosomal large subunit assembly
L	0002181	biological_process	cytoplasmic translation
L	0003723	molecular_function	RNA binding
L	0003735	molecular_function	structural constituent of ribosome
L	0005515	molecular_function	protein binding
L	0005634	cellular_component	nucleus
L	0005654	cellular_component	nucleoplasm
L	0005730	cellular_component	nucleolus
L	0005737	cellular_component	cytoplasm
L	0005829	cellular_component	cytosol
L	0005840	cellular_component	ribosome
L	0006364	biological_process	rRNA processing
L	0006412	biological_process	translation
L	0006605	biological_process	protein targeting
L	0008097	molecular_function	5S rRNA binding
L	0010628	biological_process	positive regulation of gene expression
L	0016020	cellular_component	membrane
L	0019843	molecular_function	rRNA binding
L	0022625	cellular_component	cytosolic large ribosomal subunit
L	0022626	cellular_component	cytosolic ribosome
L	0031625	molecular_function	ubiquitin protein ligase binding
L	0032092	biological_process	positive regulation of protein binding
L	0032435	biological_process	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
L	0032991	cellular_component	protein-containing complex
L	0034504	biological_process	protein localization to nucleus
L	0042273	biological_process	ribosomal large subunit biogenesis
L	0050821	biological_process	protein stabilization
L	0070062	cellular_component	extracellular exosome
L	1901796	biological_process	regulation of signal transduction by p53 class mediator
L	1901798	biological_process	positive regulation of signal transduction by p53 class mediator
L	1904667	biological_process	negative regulation of ubiquitin protein ligase activity
L	1990904	cellular_component	ribonucleoprotein complex
L	1990948	molecular_function	ubiquitin ligase inhibitor activity
L	2000059	biological_process	negative regulation of ubiquitin-dependent protein catabolic process
L	2000435	biological_process	negative regulation of protein neddylation
m	0002181	biological_process	cytoplasmic translation
m	0002227	biological_process	innate immune response in mucosa
m	0003723	molecular_function	RNA binding
m	0003735	molecular_function	structural constituent of ribosome
m	0005615	cellular_component	extracellular space
m	0005737	cellular_component	cytoplasm
m	0005829	cellular_component	cytosol
m	0005840	cellular_component	ribosome
m	0006412	biological_process	translation
m	0019731	biological_process	antibacterial humoral response
m	0022625	cellular_component	cytosolic large ribosomal subunit
m	0022626	cellular_component	cytosolic ribosome
m	0050830	biological_process	defense response to Gram-positive bacterium
m	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
m	1990904	cellular_component	ribonucleoprotein complex
M	0001824	biological_process	blastocyst development
M	0002181	biological_process	cytoplasmic translation
M	0003723	molecular_function	RNA binding
M	0003735	molecular_function	structural constituent of ribosome
M	0005515	molecular_function	protein binding
M	0005634	cellular_component	nucleus
M	0005730	cellular_component	nucleolus
M	0005737	cellular_component	cytoplasm
M	0005783	cellular_component	endoplasmic reticulum
M	0005829	cellular_component	cytosol
M	0005840	cellular_component	ribosome
M	0006412	biological_process	translation
M	0016020	cellular_component	membrane
M	0022625	cellular_component	cytosolic large ribosomal subunit
M	0022626	cellular_component	cytosolic ribosome
M	0045202	cellular_component	synapse
M	0060348	biological_process	bone development
M	1990904	cellular_component	ribonucleoprotein complex
N	0002181	biological_process	cytoplasmic translation
N	0003723	molecular_function	RNA binding
N	0003735	molecular_function	structural constituent of ribosome
N	0005515	molecular_function	protein binding
N	0005737	cellular_component	cytoplasm
N	0005829	cellular_component	cytosol
N	0005840	cellular_component	ribosome
N	0006364	biological_process	rRNA processing
N	0006412	biological_process	translation
N	0014069	cellular_component	postsynaptic density
N	0016020	cellular_component	membrane
N	0022625	cellular_component	cytosolic large ribosomal subunit
N	0022626	cellular_component	cytosolic ribosome
N	0042273	biological_process	ribosomal large subunit biogenesis
N	0045202	cellular_component	synapse
N	0045296	molecular_function	cadherin binding
N	0070062	cellular_component	extracellular exosome
N	1990904	cellular_component	ribonucleoprotein complex
o	0002181	biological_process	cytoplasmic translation
o	0003723	molecular_function	RNA binding
o	0003730	molecular_function	mRNA 3'-UTR binding
o	0003735	molecular_function	structural constituent of ribosome
o	0005515	molecular_function	protein binding
o	0005737	cellular_component	cytoplasm
o	0005783	cellular_component	endoplasmic reticulum
o	0005829	cellular_component	cytosol
o	0005840	cellular_component	ribosome
o	0006412	biological_process	translation
o	0022625	cellular_component	cytosolic large ribosomal subunit
o	0048027	molecular_function	mRNA 5'-UTR binding
o	1990904	cellular_component	ribonucleoprotein complex
O	0002181	biological_process	cytoplasmic translation
O	0003723	molecular_function	RNA binding
O	0003735	molecular_function	structural constituent of ribosome
O	0005515	molecular_function	protein binding
O	0005634	cellular_component	nucleus
O	0005737	cellular_component	cytoplasm
O	0005829	cellular_component	cytosol
O	0005840	cellular_component	ribosome
O	0006412	biological_process	translation
O	0022625	cellular_component	cytosolic large ribosomal subunit
O	0022626	cellular_component	cytosolic ribosome
O	0031672	cellular_component	A band
O	0044391	cellular_component	ribosomal subunit
O	0045202	cellular_component	synapse
O	0045296	molecular_function	cadherin binding
O	0045471	biological_process	response to ethanol
O	1990904	cellular_component	ribonucleoprotein complex
p	0003735	molecular_function	structural constituent of ribosome
p	0005840	cellular_component	ribosome
p	0006412	biological_process	translation
P	0002181	biological_process	cytoplasmic translation
P	0003723	molecular_function	RNA binding
P	0003729	molecular_function	mRNA binding
P	0003735	molecular_function	structural constituent of ribosome
P	0005634	cellular_component	nucleus
P	0005730	cellular_component	nucleolus
P	0005737	cellular_component	cytoplasm
P	0005829	cellular_component	cytosol
P	0005840	cellular_component	ribosome
P	0005925	cellular_component	focal adhesion
P	0006412	biological_process	translation
P	0006417	biological_process	regulation of translation
P	0015934	cellular_component	large ribosomal subunit
P	0016020	cellular_component	membrane
P	0017148	biological_process	negative regulation of translation
P	0022625	cellular_component	cytosolic large ribosomal subunit
P	0022626	cellular_component	cytosolic ribosome
P	0032496	biological_process	response to lipopolysaccharide
P	0042592	biological_process	homeostatic process
P	0045202	cellular_component	synapse
P	0048246	biological_process	macrophage chemotaxis
P	0060425	biological_process	lung morphogenesis
P	0071346	biological_process	cellular response to type II interferon
P	0097452	cellular_component	GAIT complex
P	1901194	biological_process	negative regulation of formation of translation preinitiation complex
P	1990904	cellular_component	ribonucleoprotein complex
q	0002181	biological_process	cytoplasmic translation
q	0003723	molecular_function	RNA binding
q	0003735	molecular_function	structural constituent of ribosome
q	0005515	molecular_function	protein binding
q	0005634	cellular_component	nucleus
q	0005737	cellular_component	cytoplasm
q	0005829	cellular_component	cytosol
q	0005840	cellular_component	ribosome
q	0005925	cellular_component	focal adhesion
q	0006412	biological_process	translation
q	0022625	cellular_component	cytosolic large ribosomal subunit
q	0022626	cellular_component	cytosolic ribosome
q	0046872	molecular_function	metal ion binding
q	0070062	cellular_component	extracellular exosome
q	1990904	cellular_component	ribonucleoprotein complex
Q	0002181	biological_process	cytoplasmic translation
Q	0003723	molecular_function	RNA binding
Q	0003735	molecular_function	structural constituent of ribosome
Q	0005515	molecular_function	protein binding
Q	0005634	cellular_component	nucleus
Q	0005737	cellular_component	cytoplasm
Q	0005829	cellular_component	cytosol
Q	0005840	cellular_component	ribosome
Q	0006412	biological_process	translation
Q	0015934	cellular_component	large ribosomal subunit
Q	0022625	cellular_component	cytosolic large ribosomal subunit
Q	0022626	cellular_component	cytosolic ribosome
Q	1990904	cellular_component	ribonucleoprotein complex
r	0002181	biological_process	cytoplasmic translation
r	0003723	molecular_function	RNA binding
r	0003735	molecular_function	structural constituent of ribosome
r	0005515	molecular_function	protein binding
r	0005737	cellular_component	cytoplasm
r	0005829	cellular_component	cytosol
r	0005840	cellular_component	ribosome
r	0006412	biological_process	translation
r	0016020	cellular_component	membrane
r	0022625	cellular_component	cytosolic large ribosomal subunit
r	0022626	cellular_component	cytosolic ribosome
r	0030425	cellular_component	dendrite
r	0036464	cellular_component	cytoplasmic ribonucleoprotein granule
r	0044297	cellular_component	cell body
r	0045202	cellular_component	synapse
r	0070062	cellular_component	extracellular exosome
r	1990904	cellular_component	ribonucleoprotein complex
R	0002181	biological_process	cytoplasmic translation
R	0003723	molecular_function	RNA binding
R	0003735	molecular_function	structural constituent of ribosome
R	0005515	molecular_function	protein binding
R	0005634	cellular_component	nucleus
R	0005730	cellular_component	nucleolus
R	0005737	cellular_component	cytoplasm
R	0005783	cellular_component	endoplasmic reticulum
R	0005791	cellular_component	rough endoplasmic reticulum
R	0005829	cellular_component	cytosol
R	0005840	cellular_component	ribosome
R	0005925	cellular_component	focal adhesion
R	0006412	biological_process	translation
R	0016020	cellular_component	membrane
R	0022625	cellular_component	cytosolic large ribosomal subunit
R	0022626	cellular_component	cytosolic ribosome
R	0043232	cellular_component	intracellular non-membrane-bounded organelle
R	1990904	cellular_component	ribonucleoprotein complex
S	0002181	biological_process	cytoplasmic translation
S	0003723	molecular_function	RNA binding
S	0003735	molecular_function	structural constituent of ribosome
S	0005515	molecular_function	protein binding
S	0005730	cellular_component	nucleolus
S	0005737	cellular_component	cytoplasm
S	0005829	cellular_component	cytosol
S	0005840	cellular_component	ribosome
S	0005925	cellular_component	focal adhesion
S	0006412	biological_process	translation
S	0016020	cellular_component	membrane
S	0022625	cellular_component	cytosolic large ribosomal subunit
S	0022626	cellular_component	cytosolic ribosome
S	0045202	cellular_component	synapse
S	1990904	cellular_component	ribonucleoprotein complex
T	0002181	biological_process	cytoplasmic translation
T	0003723	molecular_function	RNA binding
T	0003735	molecular_function	structural constituent of ribosome
T	0005515	molecular_function	protein binding
T	0005737	cellular_component	cytoplasm
T	0005829	cellular_component	cytosol
T	0005840	cellular_component	ribosome
T	0006412	biological_process	translation
T	0016020	cellular_component	membrane
T	0022625	cellular_component	cytosolic large ribosomal subunit
T	0022626	cellular_component	cytosolic ribosome
T	1990904	cellular_component	ribonucleoprotein complex
U	0002181	biological_process	cytoplasmic translation
U	0003723	molecular_function	RNA binding
U	0003735	molecular_function	structural constituent of ribosome
U	0005515	molecular_function	protein binding
U	0005737	cellular_component	cytoplasm
U	0005783	cellular_component	endoplasmic reticulum
U	0005829	cellular_component	cytosol
U	0005840	cellular_component	ribosome
U	0006412	biological_process	translation
U	0016020	cellular_component	membrane
U	0022625	cellular_component	cytosolic large ribosomal subunit
U	0022626	cellular_component	cytosolic ribosome
U	0045202	cellular_component	synapse
U	1990904	cellular_component	ribonucleoprotein complex
V	0002181	biological_process	cytoplasmic translation
V	0003723	molecular_function	RNA binding
V	0003735	molecular_function	structural constituent of ribosome
V	0005515	molecular_function	protein binding
V	0005634	cellular_component	nucleus
V	0005737	cellular_component	cytoplasm
V	0005829	cellular_component	cytosol
V	0005840	cellular_component	ribosome
V	0005925	cellular_component	focal adhesion
V	0006412	biological_process	translation
V	0008201	molecular_function	heparin binding
V	0022625	cellular_component	cytosolic large ribosomal subunit
V	0022626	cellular_component	cytosolic ribosome
V	0042802	molecular_function	identical protein binding
V	0045202	cellular_component	synapse
V	0046632	biological_process	alpha-beta T cell differentiation
V	0070062	cellular_component	extracellular exosome
V	0098793	cellular_component	presynapse
V	0098978	cellular_component	glutamatergic synapse
V	0140236	biological_process	translation at presynapse
V	1990904	cellular_component	ribonucleoprotein complex
W	0003735	molecular_function	structural constituent of ribosome
W	0005840	cellular_component	ribosome
W	0006412	biological_process	translation
X	0002181	biological_process	cytoplasmic translation
X	0003723	molecular_function	RNA binding
X	0003729	molecular_function	mRNA binding
X	0003735	molecular_function	structural constituent of ribosome
X	0005515	molecular_function	protein binding
X	0005737	cellular_component	cytoplasm
X	0005783	cellular_component	endoplasmic reticulum
X	0005829	cellular_component	cytosol
X	0005840	cellular_component	ribosome
X	0006412	biological_process	translation
X	0010458	biological_process	exit from mitosis
X	0016020	cellular_component	membrane
X	0021554	biological_process	optic nerve development
X	0022625	cellular_component	cytosolic large ribosomal subunit
X	0022626	cellular_component	cytosolic ribosome
X	0031290	biological_process	retinal ganglion cell axon guidance
X	0045202	cellular_component	synapse
X	0045296	molecular_function	cadherin binding
X	0060041	biological_process	retina development in camera-type eye
X	0070062	cellular_component	extracellular exosome
X	1990904	cellular_component	ribonucleoprotein complex
Y	0000027	biological_process	ribosomal large subunit assembly
Y	0002181	biological_process	cytoplasmic translation
Y	0003723	molecular_function	RNA binding
Y	0003735	molecular_function	structural constituent of ribosome
Y	0005515	molecular_function	protein binding
Y	0005634	cellular_component	nucleus
Y	0005730	cellular_component	nucleolus
Y	0005737	cellular_component	cytoplasm
Y	0005829	cellular_component	cytosol
Y	0005840	cellular_component	ribosome
Y	0006412	biological_process	translation
Y	0019843	molecular_function	rRNA binding
Y	0022625	cellular_component	cytosolic large ribosomal subunit
Y	0022626	cellular_component	cytosolic ribosome
Y	0045296	molecular_function	cadherin binding
Y	0070062	cellular_component	extracellular exosome
Y	1904841	molecular_function	TORC2 complex binding
Y	1990904	cellular_component	ribonucleoprotein complex
Z	0002181	biological_process	cytoplasmic translation
Z	0003723	molecular_function	RNA binding
Z	0003735	molecular_function	structural constituent of ribosome
Z	0005515	molecular_function	protein binding
Z	0005654	cellular_component	nucleoplasm
Z	0005730	cellular_component	nucleolus
Z	0005737	cellular_component	cytoplasm
Z	0005829	cellular_component	cytosol
Z	0005840	cellular_component	ribosome
Z	0006364	biological_process	rRNA processing
Z	0006412	biological_process	translation
Z	0006977	biological_process	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
Z	0015934	cellular_component	large ribosomal subunit
Z	0016020	cellular_component	membrane
Z	0022625	cellular_component	cytosolic large ribosomal subunit
Z	0022626	cellular_component	cytosolic ribosome
Z	0034644	biological_process	cellular response to UV
Z	0042273	biological_process	ribosomal large subunit biogenesis
Z	0045202	cellular_component	synapse
Z	0045727	biological_process	positive regulation of translation
Z	0048027	molecular_function	mRNA 5'-UTR binding
Z	0070062	cellular_component	extracellular exosome
Z	0071479	biological_process	cellular response to ionizing radiation
Z	0071480	biological_process	cellular response to gamma radiation
Z	1902164	biological_process	positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
Z	1902167	biological_process	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
Z	1904803	biological_process	regulation of translation involved in cellular response to UV
Z	1990904	cellular_component	ribonucleoprotein complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue MG B 501

Chain	Residue
B	LYS30
B	SER31
t	C4676
t	C4677

---

site_id	AC2
Number of Residues	1
Details	binding site for residue MG D 201

Chain	Residue
D	C35

---

site_id	AC3
Number of Residues	3
Details	binding site for residue MG D 202

Chain	Residue
D	C117
D	G133
D	G134

---

site_id	AC4
Number of Residues	1
Details	binding site for residue MG D 204

Chain	Residue
D	A20

---

site_id	AC5
Number of Residues	4
Details	binding site for residue MG E 201

Chain	Residue
E	A54
E	A55
E	MG204
L	LYS154

---

site_id	AC6
Number of Residues	2
Details	binding site for residue MG E 202

Chain	Residue
E	G81
E	G82

---

site_id	AC7
Number of Residues	3
Details	binding site for residue MG E 203

Chain	Residue
E	G64
E	G65
E	U109

---

site_id	AC8
Number of Residues	4
Details	binding site for residue MG E 204

Chain	Residue
E	U53
E	A54
E	A55
E	MG201

---

site_id	AC9
Number of Residues	3
Details	binding site for residue MG E 205

Chain	Residue
E	A83
E	U84
t	G1876

---

site_id	AD1
Number of Residues	2
Details	binding site for residue MG E 206

Chain	Residue
E	G61
E	U62

---

site_id	AD2
Number of Residues	2
Details	binding site for residue MG E 207

Chain	Residue
E	G37
E	U38

---

site_id	AD3
Number of Residues	2
Details	binding site for residue MG E 208

Chain	Residue
E	G37
E	U38

---

site_id	AD4
Number of Residues	3
Details	binding site for residue MG E 209

Chain	Residue
E	A32
E	G41
E	A42

---

site_id	AD5
Number of Residues	4
Details	binding site for residue ZN k 102

Chain	Residue
k	CYS19
k	CYS22
k	CYS34
k	CYS37

---

site_id	AD6
Number of Residues	4
Details	binding site for residue ZN p 201

Chain	Residue
p	CYS12
p	GLN19
p	CYS72
p	CYS77

---

site_id	AD7
Number of Residues	5
Details	binding site for residue ZN q 101

Chain	Residue
q	CYS39
q	CYS42
q	CYS57
q	SER59
q	CYS60

---

site_id	AD8
Number of Residues	5
Details	binding site for residue MG t 5101

Chain	Residue
A	ARG198
t	C3621
t	A3622
t	A3623
t	G3662

---

site_id	AD9
Number of Residues	4
Details	binding site for residue MG t 5102

Chain	Residue
b	GLY18
t	A1831
t	G2262
t	G2263

---

site_id	AE1
Number of Residues	2
Details	binding site for residue MG t 5103

Chain	Residue
t	G1861
t	C1862

---

site_id	AE2
Number of Residues	2
Details	binding site for residue MG t 5105

Chain	Residue
t	A347
t	U348

---

site_id	AE3
Number of Residues	3
Details	binding site for residue MG t 5106

Chain	Residue
t	G1508
t	A1509
t	U1510

---

site_id	AE4
Number of Residues	1
Details	binding site for residue MG t 5108

Chain	Residue
t	A2261

---

site_id	AE5
Number of Residues	3
Details	binding site for residue MG t 5109

Chain	Residue
t	G1662
t	G1663
t	G1834

---

site_id	AE6
Number of Residues	4
Details	binding site for residue MG t 5110

Chain	Residue
f	ASP42
t	U1300
t	A1305
t	A1309

---

Functional Information from PROSITE/UniProt

site_id	PS00049
Number of Residues	27
Details	RIBOSOMAL_L14 Ribosomal protein L14 signature. AVVIrqrksyrrk.DGvflyFedNagVI

Chain	Residue	Details
W	ALA79-ILE105

---

site_id	PS00050
Number of Residues	16
Details	RIBOSOMAL_L23 Ribosomal protein L23 signature. KKAYVRLApdydaldV

Chain	Residue	Details
Y	LYS134-VAL149

---

site_id	PS00051
Number of Residues	17
Details	RIBOSOMAL_L39E Ribosomal protein L39e signature. KTgnkIryNskrRHWRR

Chain	Residue	Details
m	LYS30-ARG46

---

site_id	PS00358
Number of Residues	17
Details	RIBOSOMAL_L5 Ribosomal protein L5 signature. LeqLTGQtpVfSkARyT

Chain	Residue	Details
L	LEU40-THR56

---

site_id	PS00464
Number of Residues	25
Details	RIBOSOMAL_L22 Ribosomal protein L22 signature. RrrTyRAhGRinpymsspCHIEMiL

Chain	Residue	Details
Q	ARG126-LEU150

---

site_id	PS00467
Number of Residues	12
Details	RIBOSOMAL_L2 Ribosomal protein L2 signature. PrvRGVAmNPvE

Chain	Residue	Details
A	PRO197-GLU208

---

site_id	PS00474
Number of Residues	24
Details	RIBOSOMAL_L3 Ribosomal protein L3 signature. FgqdemiDviGvTkGKGykGvtsR

Chain	Residue	Details
B	PHE211-ARG234

---

site_id	PS00475
Number of Residues	32
Details	RIBOSOMAL_L15 Ribosomal protein L15 signature. KVLGkGkLpkqp.ViVkakfFSrrAeekIksvG

Chain	Residue	Details
b	LYS110-GLY141

---

site_id	PS00526
Number of Residues	20
Details	RIBOSOMAL_L19E Ribosomal protein L19e signature. QKRLaSsvlrCGkkkVWLDP

Chain	Residue	Details
S	GLN7-PRO26

---

site_id	PS00579
Number of Residues	15
Details	RIBOSOMAL_L29 Ribosomal protein L29 signature. KLSKIRvVRKSIARV

Chain	Residue	Details
i	LYS43-VAL57

---

site_id	PS00580
Number of Residues	21
Details	RIBOSOMAL_L32E Ribosomal protein L32e signature. FiRhqsdRyvKIkrn..WRKprG

Chain	Residue	Details
f	PHE20-GLY40

---

site_id	PS00634
Number of Residues	33
Details	RIBOSOMAL_L30 Ribosomal protein L30 signature. VLqlLrLrQifNgTfvklnkasinMLriVepYI

Chain	Residue	Details
H	VAL108-ILE140

---

site_id	PS00687
Number of Residues	8
Details	ALDEHYDE_DEHYDR_GLU Aldehyde dehydrogenases glutamic acid active site. GESSGKNV

Chain	Residue	Details
C	GLY15-VAL22

---

site_id	PS00700
Number of Residues	22
Details	RIBOSOMAL_L6_2 Ribosomal protein L6 signature 2. QattVknKdiRkFlDGIYVseK

Chain	Residue	Details
J	GLN163-LYS184

---

site_id	PS00709
Number of Residues	25
Details	RIBOSOMAL_L30E_1 Ribosomal protein L30e signature 1. SgkyvlGyKqtLKmiRqGkaKlVIL

Chain	Residue	Details
d	SER24-LEU48

---

site_id	PS00755
Number of Residues	20
Details	SECY_1 Protein secY signature 1. TLMeLGIsPIVtSGLIMQLL

Chain	Residue	Details
1	THR75-LEU94

---

site_id	PS00756
Number of Residues	19
Details	SECY_2 Protein secY signature 2. LLdElLQkgyGLGSGiSLF

Chain	Residue	Details
1	LEU164-PHE182

---

site_id	PS00783
Number of Residues	24
Details	RIBOSOMAL_L13 Ribosomal protein L13 signature. VRGMLPhktkrGQaaldrLkVFdG

Chain	Residue	Details
P	VAL84-GLY107

---

site_id	PS00939
Number of Residues	27
Details	RIBOSOMAL_L1E Ribosomal protein L1e signature. NttqKryAIcSALaASAlpalvmsKGH

Chain	Residue	Details
C	ASN116-HIS142

---

site_id	PS00993
Number of Residues	21
Details	RIBOSOMAL_L30E_2 Ribosomal protein L30e signature 2. ELGTacGKyyrvctLaIiDpG

Chain	Residue	Details
d	GLU80-GLY100

---

site_id	PS01067
Number of Residues	29
Details	SECE_SEC61G Protein secE/sec61-gamma signature. FvKDsIrlVkRctKPdrkEfqkiaMATAI

Chain	Residue	Details
2	PHE14-ILE42

---

site_id	PS01073
Number of Residues	18
Details	RIBOSOMAL_L24E Ribosomal protein L24e signature. FsGykIyPGhGrrYaRtD

Chain	Residue	Details
X	PHE8-ASP25

---

site_id	PS01077
Number of Residues	20
Details	RIBOSOMAL_L37E Ribosomal protein L37e signature. GTsSfGkRrnkt.HtlCrRCG

Chain	Residue	Details
k	GLY4-GLY23

---

site_id	PS01082
Number of Residues	18
Details	RIBOSOMAL_L7AE Ribosomal protein L7Ae signature. CrkmgVPYciIkGKarLG

Chain	Residue	Details
I	CYS174-GLY191

---

site_id	PS01104
Number of Residues	15
Details	RIBOSOMAL_L13E Ribosomal protein L13e signature. RaGRGFSLeELrvaG

Chain	Residue	Details
M	ARG71-GLY85

---

site_id	PS01105
Number of Residues	22
Details	RIBOSOMAL_L35AE Ribosomal protein L35Ae signature. GKVtRaHGnsGmVrAkFrsnLP

Chain	Residue	Details
g	GLY72-PRO93

---

site_id	PS01106
Number of Residues	18
Details	RIBOSOMAL_L18E Ribosomal protein L18e signature. KrLfmSRtnRPpLSLsRM

Chain	Residue	Details
R	LYS49-MET66

---

site_id	PS01107
Number of Residues	12
Details	RIBOSOMAL_L27E Ribosomal protein L27e signature. GKNkWFFqkLRF

Chain	Residue	Details
a	GLY125-PHE136

---

site_id	PS01108
Number of Residues	19
Details	RIBOSOMAL_L24 Ribosomal protein L24 signature. DDeVqVVrGhyKGqqiGkV

Chain	Residue	Details
Z	ASP52-VAL70

---

site_id	PS01144
Number of Residues	15
Details	RIBOSOMAL_L31E Ribosomal protein L31e signature. VRIDtrLNkAvWaKG

Chain	Residue	Details
e	VAL62-GLY76

---

site_id	PS01145
Number of Residues	14
Details	RIBOSOMAL_L34E Ribosomal protein L34e signature. TaSnKtrlsRTPGN

Chain	Residue	Details
h	THR15-ASN28

---

site_id	PS01170
Number of Residues	19
Details	RIBOSOMAL_L6E Ribosomal protein L6e signature. NrvPLRRthqkFVIATSt.K

Chain	Residue	Details
G	ASN182-LYS200

---

site_id	PS01171
Number of Residues	26
Details	RIBOSOMAL_L21E Ribosomal protein L21e signature. GDiVdikgmgtvqk.GmpHkcYhGkTG

Chain	Residue	Details
U	GLY37-GLY62

---

site_id	PS01172
Number of Residues	12
Details	RIBOSOMAL_L44E Ribosomal protein L44e signature. KtTKKivLRleC

Chain	Residue	Details
p	LYS61-CYS72

---

site_id	PS01190
Number of Residues	11
Details	RIBOSOMAL_L36E Ribosomal protein L36e signature. PYERRaMELLK

Chain	Residue	Details
j	PRO52-LYS62

---

site_id	PS01194
Number of Residues	24
Details	RIBOSOMAL_L15E Ribosomal protein L15e signature. DKARrLGYkAkqGYVIYRiRVrRG

Chain	Residue	Details
O	ASP46-GLY69

---

site_id	PS01257
Number of Residues	22
Details	RIBOSOMAL_L10E Ribosomal protein L10e signature. ADRlqtGMRgAFGKPqGtvARV

Chain	Residue	Details
K	ALA108-VAL129

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	67
Details	TRANSMEM: Helical => ECO:0000250|UniProtKB:A0A8I3PI99

Chain	Residue	Details
6	PHE5-ARG32
6	ARG87-ASN106
6	CYS141-LEU162
4	ILE99-ARG124
4	TRP130-MET155
4	PHE165-VAL187
4	TRP195-TYR216

---

site_id	SWS_FT_FI2
Number of Residues	78
Details	TOPO_DOM: Cytoplasmic => ECO:0000250|UniProtKB:A0A8I3PI99

Chain	Residue	Details
6	THR33-VAL86
1	GLY446-VAL462
6	GLY163-SER188
4	ILE156-THR164
4	VAL217-SER224
1	TYR173-TRP193
1	ASN241-PHE261
1	ILE289-SER309
1	LEU355-PHE375
1	ALA421-ILE441

---

site_id	SWS_FT_FI3
Number of Residues	22
Details	TOPO_DOM: Lumenal => ECO:0000250|UniProtKB:A0A8I3PI99

Chain	Residue	Details
6	SER107-THR120
6	ARG131-ASP140
4	HIS188-SER194
1	ALA310-VAL354
1	GLY442-THR445
I	LYS125
I	LYS245

---

site_id	SWS_FT_FI4
Number of Residues	9
Details	INTRAMEM: INTRAMEM => ECO:0000250|UniProtKB:A0A8I3PI99

Chain	Residue	Details
6	PRO121-HIS130
5	ASN428

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231

Chain	Residue	Details
6	SER60
B	LYS366

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:18691976, ECO:0007744|PubMed:20068231

Chain	Residue	Details
6	SER188
T	LYS128
T	LYS170

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648

Chain	Residue	Details
3	SER13
M	LYS174
M	LYS177
B	LYS386
B	LYS393

---

site_id	SWS_FT_FI8
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:23186163

Chain	Residue	Details
3	SER14
B	LYS399
X	LYS35
X	LYS147

---

site_id	SWS_FT_FI9
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569

Chain	Residue	Details
3	SER17
B	LYS366

---

site_id	SWS_FT_FI10
Number of Residues	1
Details	LIPID: S-palmitoyl cysteine => ECO:0000305|PubMed:21044946

Chain	Residue	Details
3	CYS39

---

site_id	SWS_FT_FI11
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733

Chain	Residue	Details
C	LYS239
C	LYS327

---

site_id	SWS_FT_FI12
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1); alternate => ECO:0007744|PubMed:25114211

Chain	Residue	Details
C	LYS364

---