6W51
Structure of the antibody fragment H2 in complex with HLA-A*02:01/p53R175H
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0006955 | biological_process | immune response |
| B | 0042612 | cellular_component | MHC class I protein complex |
| E | 0006955 | biological_process | immune response |
| E | 0042612 | cellular_component | MHC class I protein complex |
| H | 0006955 | biological_process | immune response |
| H | 0042612 | cellular_component | MHC class I protein complex |
| K | 0006955 | biological_process | immune response |
| K | 0042612 | cellular_component | MHC class I protein complex |
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH |
| Chain | Residue | Details |
| N | TYR193-HIS199 | |
| M | TYR202-HIS208 | |
| A | TYR257-HIS263 | |
| B | TYR78-HIS84 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:14534297, ECO:0000269|PubMed:16793544, ECO:0000269|PubMed:17015838, ECO:0000269|PubMed:18650397, ECO:0000269|PubMed:19515728, ECO:0000269|PubMed:20142040, ECO:0000269|PubMed:20364130 |
| Chain | Residue | Details |
| C | CYS9 | |
| F | CYS9 | |
| I | CYS9 | |
| L | CYS9 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | CARBOHYD: N-linked (Glc) (glycation) isoleucine; in hemodialysis-associated amyloidosis => ECO:0000269|PubMed:7918443 |
| Chain | Residue | Details |
| B | ILE1 | |
| E | ILE1 | |
| H | ILE1 | |
| K | ILE1 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 24 |
| Details | CARBOHYD: N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269|PubMed:7918443 |
| Chain | Residue | Details |
| B | LYS19 | |
| E | LYS58 | |
| E | LYS91 | |
| E | LYS94 | |
| H | LYS19 | |
| H | LYS41 | |
| H | LYS48 | |
| H | LYS58 | |
| H | LYS91 | |
| H | LYS94 | |
| K | LYS19 | |
| B | LYS41 | |
| K | LYS41 | |
| K | LYS48 | |
| K | LYS58 | |
| K | LYS91 | |
| K | LYS94 | |
| B | LYS48 | |
| B | LYS58 | |
| B | LYS91 | |
| B | LYS94 | |
| E | LYS19 | |
| E | LYS41 | |
| E | LYS48 |
