6W4M

CRYSTAL STRUCTURE OF THE ADCC-POTENT, WEAKLY NEUTRALIZING HIV ENV CO-RECEPTOR BINDING SITE ANTIBODY N12-I2 FAB IN COMPLEX WITH HIV-1 CLADE A/E GP120 AND M48U1

Replaces:  5UWE

Functional Information from GO Data

Chain	GOid	namespace	contents
G	0019031	cellular_component	viral envelope
G	0019062	biological_process	virion attachment to host cell
G	0039654	biological_process	fusion of virus membrane with host endosome membrane
G	0039663	biological_process	membrane fusion involved in viral entry into host cell
G	0046718	biological_process	symbiont entry into host cell
G	0055036	cellular_component	virion membrane
G	0075509	biological_process	endocytosis involved in viral entry into host cell
G	0075512	biological_process	clathrin-dependent endocytosis of virus by host cell

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH

Chain	Residue	Details
H	TYR194-HIS200
L	TYR192-HIS198

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