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6VKA

HIV Integrase Core domain (IN) in complex with dimer-spanning ligand

Functional Information from GO Data
ChainGOidnamespacecontents
A0003676molecular_functionnucleic acid binding
A0015074biological_processDNA integration
B0003676molecular_functionnucleic acid binding
B0015074biological_processDNA integration
Functional Information from PDB Data
site_idAC1
Number of Residues2
Detailsbinding site for residue IOD A 302
ChainResidue
AGLY70
BTYR194

site_idAC2
Number of Residues19
Detailsbinding site for residue QZV A 303
ChainResidue
AHIS171
ATHR174
BGLN95
BGLU96
BALA98
BTYR99
BTHR125
BALA129
BGLU170
BHIS171
BLYS173
BTHR174
AGLN95
AGLU96
ATYR99
ATHR125
AALA129
AALA169
AGLU170

site_idAC3
Number of Residues5
Detailsbinding site for residue SO4 A 304
ChainResidue
ATHR66
AHIS67
ALYS159
AHOH404
BHOH402

site_idAC4
Number of Residues7
Detailsbinding site for residue SO4 A 305
ChainResidue
ATHR93
AGLY94
ASER123
ATHR124
ATHR125
AHOH413
AHOH425

site_idAC5
Number of Residues4
Detailsbinding site for residue SO4 A 306
ChainResidue
APRO109
BTHR122
BLYS127
BLYS185

site_idAC6
Number of Residues6
Detailsbinding site for residue SO4 A 307
ChainResidue
APRO90
AGLU92
AGLY94
AGLN95
AGLU96
AHOH413

site_idAC7
Number of Residues6
Detailsbinding site for residue SO4 A 308
ChainResidue
AGLU87
ATYR99
APHE100
ALYS103
AHOH405
BLYS103

site_idAC8
Number of Residues1
Detailsbinding site for residue IOD A 309
ChainResidue
AARG187

site_idAC9
Number of Residues1
Detailsbinding site for residue IOD B 301
ChainResidue
BLYS173

site_idAD1
Number of Residues2
Detailsbinding site for residue SO4 B 303
ChainResidue
BTHR66
BHIS67

site_idAD2
Number of Residues5
Detailsbinding site for residue SO4 B 304
ChainResidue
BLEU68
BLYS159
BILE162
BGLY163
BARG166

site_idAD3
Number of Residues5
Detailsbinding site for residue SO4 B 305
ChainResidue
BSER57
BPRO58
BGLY59
BILE60
BLYS111

site_idAD4
Number of Residues4
Detailsbinding site for residue SO4 B 306
ChainResidue
BGLY94
BSER123
BTHR124
BTHR125

site_idAD5
Number of Residues6
Detailsbinding site for residue SO4 B 307
ChainResidue
ALYS103
BGLU87
BTYR99
BPHE100
BLYS103
BHOH404

site_idAD6
Number of Residues1
Detailsbinding site for residue IOD B 308
ChainResidue
BGLY70

226707

PDB entries from 2024-10-30

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