6VEO
ATAD2B bromodomain in complex with 4-({[(3R,4R)-4-{[3-methyl-5-(5-methylpyridin-3-yl)-2-oxo-1,2-dihydro-1,7-naphthyridin-8-yl]amino}piperidin-3-yl]oxy}methyl)-1lambda~6~-thiane-1,1-dione (compound 38)
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 1101 |
| Chain | Residue |
| A | LYS1011 |
| A | LYS1021 |
| A | LYS1025 |
| A | LYS1079 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 1102 |
| Chain | Residue |
| A | ARG961 |
| A | ARG964 |
| A | ARG968 |
| A | HIS1015 |
| site_id | AC3 |
| Number of Residues | 13 |
| Details | binding site for residue YD4 A 1103 |
| Chain | Residue |
| A | VAL987 |
| A | ASP988 |
| A | VAL992 |
| A | TYR1037 |
| A | ASN1038 |
| A | ASP1042 |
| A | GLY1044 |
| A | ASP1045 |
| A | ILE1048 |
| A | ARG1051 |
| A | HOH1213 |
| A | HOH1248 |
| A | ILE982 |
Functional Information from PROSITE/UniProt
| site_id | PS00633 |
| Number of Residues | 58 |
| Details | BROMODOMAIN_1 Bromodomain signature. FniFskpvDieevs..DYLevIkepMdlstVitkidkhn..Yltakdflkdidl.IcsNAleY |
| Chain | Residue | Details |
| A | PHE980-TYR1037 | |
