6UWH

Intermediate engineered variant of I-OnuI meganuclease with improved thermostability and partially altered specificity

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004519	molecular_function	endonuclease activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue CA A 401

Chain	Residue
A	ALA21
A	ASP178
A	HOH512
B	DC14
C	DA16
C	HOH207

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site_id	AC2
Number of Residues	7
Details	binding site for residue CA A 402

Chain	Residue
A	HOH521
B	DG15
B	HOH102
C	HOH204
A	GLU22
A	GLY177
A	HOH510

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site_id	AC3
Number of Residues	4
Details	binding site for residue CA A 403

Chain	Residue
A	PHE182
A	LYS294
B	DC17
B	DC18

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site_id	AC4
Number of Residues	1
Details	binding site for residue EDO A 404

Chain	Residue
A	LYS54

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site_id	AC5
Number of Residues	6
Details	binding site for residue CA C 101

Chain	Residue
A	GLU22
A	THR48
A	HOH514
C	DT15
C	DA16
C	HOH201

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