6UMG

Crystal structure of erenumab Fab bound to the extracellular domain of CGRP receptor

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0004930	molecular_function	G protein-coupled receptor activity
C	0004948	molecular_function	calcitonin receptor activity
C	0007186	biological_process	G protein-coupled receptor signaling pathway
C	0016020	cellular_component	membrane
R	0006886	biological_process	intracellular protein transport
R	0008277	biological_process	regulation of G protein-coupled receptor signaling pathway
R	0015026	molecular_function	coreceptor activity
R	0016020	cellular_component	membrane
c	0004930	molecular_function	G protein-coupled receptor activity
c	0004948	molecular_function	calcitonin receptor activity
c	0007186	biological_process	G protein-coupled receptor signaling pathway
c	0016020	cellular_component	membrane
r	0006886	biological_process	intracellular protein transport
r	0008277	biological_process	regulation of G protein-coupled receptor signaling pathway
r	0015026	molecular_function	coreceptor activity
r	0016020	cellular_component	membrane

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YSCQVTH

Chain	Residue	Details
L	TYR195-HIS201
H	TYR211-HIS217

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site_id	PS00649
Number of Residues	25
Details	G_PROTEIN_RECEP_F2_1 G-protein coupled receptors family 2 signature 1. CnrtWDgwl.CWndVaagtesmqlCP

Chain	Residue	Details
C	CYS65-PRO89

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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