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6U2L

EM structure of MPEG-1 (L425K, beta conformation) soluble pre-pore complex

This is a non-PDB format compatible entry.
Functional Information from GO Data
ChainGOidnamespacecontents
A0002250biological_processadaptive immune response
A0002376biological_processimmune system process
A0002468biological_processdendritic cell antigen processing and presentation
A0002478biological_processantigen processing and presentation of exogenous peptide antigen
A0005576cellular_componentextracellular region
A0022829molecular_functionwide pore channel activity
A0030659cellular_componentcytoplasmic vesicle membrane
A0030670cellular_componentphagocytic vesicle membrane
A0031410cellular_componentcytoplasmic vesicle
A0042590biological_processantigen processing and presentation of exogenous peptide antigen via MHC class I
A0042742biological_processdefense response to bacterium
A0045087biological_processinnate immune response
A0045335cellular_componentphagocytic vesicle
A0050829biological_processdefense response to Gram-negative bacterium
A0050830biological_processdefense response to Gram-positive bacterium
A0055085biological_processtransmembrane transport
A0061474cellular_componentphagolysosome membrane
A0140367biological_processantibacterial innate immune response
AA0002250biological_processadaptive immune response
AA0002376biological_processimmune system process
AA0002468biological_processdendritic cell antigen processing and presentation
AA0002478biological_processantigen processing and presentation of exogenous peptide antigen
AA0005576cellular_componentextracellular region
AA0022829molecular_functionwide pore channel activity
AA0030659cellular_componentcytoplasmic vesicle membrane
AA0030670cellular_componentphagocytic vesicle membrane
AA0031410cellular_componentcytoplasmic vesicle
AA0042590biological_processantigen processing and presentation of exogenous peptide antigen via MHC class I
AA0042742biological_processdefense response to bacterium
AA0045087biological_processinnate immune response
AA0045335cellular_componentphagocytic vesicle
AA0050829biological_processdefense response to Gram-negative bacterium
AA0050830biological_processdefense response to Gram-positive bacterium
AA0055085biological_processtransmembrane transport
AA0061474cellular_componentphagolysosome membrane
AA0140367biological_processantibacterial innate immune response
B0002250biological_processadaptive immune response
B0002376biological_processimmune system process
B0002468biological_processdendritic cell antigen processing and presentation
B0002478biological_processantigen processing and presentation of exogenous peptide antigen
B0005576cellular_componentextracellular region
B0022829molecular_functionwide pore channel activity
B0030659cellular_componentcytoplasmic vesicle membrane
B0030670cellular_componentphagocytic vesicle membrane
B0031410cellular_componentcytoplasmic vesicle
B0042590biological_processantigen processing and presentation of exogenous peptide antigen via MHC class I
B0042742biological_processdefense response to bacterium
B0045087biological_processinnate immune response
B0045335cellular_componentphagocytic vesicle
B0050829biological_processdefense response to Gram-negative bacterium
B0050830biological_processdefense response to Gram-positive bacterium
B0055085biological_processtransmembrane transport
B0061474cellular_componentphagolysosome membrane
B0140367biological_processantibacterial innate immune response
BB0002250biological_processadaptive immune response
BB0002376biological_processimmune system process
BB0002468biological_processdendritic cell antigen processing and presentation
BB0002478biological_processantigen processing and presentation of exogenous peptide antigen
BB0005576cellular_componentextracellular region
BB0022829molecular_functionwide pore channel activity
BB0030659cellular_componentcytoplasmic vesicle membrane
BB0030670cellular_componentphagocytic vesicle membrane
BB0031410cellular_componentcytoplasmic vesicle
BB0042590biological_processantigen processing and presentation of exogenous peptide antigen via MHC class I
BB0042742biological_processdefense response to bacterium
BB0045087biological_processinnate immune response
BB0045335cellular_componentphagocytic vesicle
BB0050829biological_processdefense response to Gram-negative bacterium
BB0050830biological_processdefense response to Gram-positive bacterium
BB0055085biological_processtransmembrane transport
BB0061474cellular_componentphagolysosome membrane
BB0140367biological_processantibacterial innate immune response
C0002250biological_processadaptive immune response
C0002376biological_processimmune system process
C0002468biological_processdendritic cell antigen processing and presentation
C0002478biological_processantigen processing and presentation of exogenous peptide antigen
C0005576cellular_componentextracellular region
C0022829molecular_functionwide pore channel activity
C0030659cellular_componentcytoplasmic vesicle membrane
C0030670cellular_componentphagocytic vesicle membrane
C0031410cellular_componentcytoplasmic vesicle
C0042590biological_processantigen processing and presentation of exogenous peptide antigen via MHC class I
C0042742biological_processdefense response to bacterium
C0045087biological_processinnate immune response
C0045335cellular_componentphagocytic vesicle
C0050829biological_processdefense response to Gram-negative bacterium
C0050830biological_processdefense response to Gram-positive bacterium
C0055085biological_processtransmembrane transport
C0061474cellular_componentphagolysosome membrane
C0140367biological_processantibacterial innate immune response
CC0002250biological_processadaptive immune response
CC0002376biological_processimmune system process
CC0002468biological_processdendritic cell antigen processing and presentation
CC0002478biological_processantigen processing and presentation of exogenous peptide antigen
CC0005576cellular_componentextracellular region
CC0022829molecular_functionwide pore channel activity
CC0030659cellular_componentcytoplasmic vesicle membrane
CC0030670cellular_componentphagocytic vesicle membrane
CC0031410cellular_componentcytoplasmic vesicle
CC0042590biological_processantigen processing and presentation of exogenous peptide antigen via MHC class I
CC0042742biological_processdefense response to bacterium
CC0045087biological_processinnate immune response
CC0045335cellular_componentphagocytic vesicle
CC0050829biological_processdefense response to Gram-negative bacterium
CC0050830biological_processdefense response to Gram-positive bacterium
CC0055085biological_processtransmembrane transport
CC0061474cellular_componentphagolysosome membrane
CC0140367biological_processantibacterial innate immune response
D0002250biological_processadaptive immune response
D0002376biological_processimmune system process
D0002468biological_processdendritic cell antigen processing and presentation
D0002478biological_processantigen processing and presentation of exogenous peptide antigen
D0005576cellular_componentextracellular region
D0022829molecular_functionwide pore channel activity
D0030659cellular_componentcytoplasmic vesicle membrane
D0030670cellular_componentphagocytic vesicle membrane
D0031410cellular_componentcytoplasmic vesicle
D0042590biological_processantigen processing and presentation of exogenous peptide antigen via MHC class I
D0042742biological_processdefense response to bacterium
D0045087biological_processinnate immune response
D0045335cellular_componentphagocytic vesicle
D0050829biological_processdefense response to Gram-negative bacterium
D0050830biological_processdefense response to Gram-positive bacterium
D0055085biological_processtransmembrane transport
D0061474cellular_componentphagolysosome membrane
D0140367biological_processantibacterial innate immune response
DD0002250biological_processadaptive immune response
DD0002376biological_processimmune system process
DD0002468biological_processdendritic cell antigen processing and presentation
DD0002478biological_processantigen processing and presentation of exogenous peptide antigen
DD0005576cellular_componentextracellular region
DD0022829molecular_functionwide pore channel activity
DD0030659cellular_componentcytoplasmic vesicle membrane
DD0030670cellular_componentphagocytic vesicle membrane
DD0031410cellular_componentcytoplasmic vesicle
DD0042590biological_processantigen processing and presentation of exogenous peptide antigen via MHC class I
DD0042742biological_processdefense response to bacterium
DD0045087biological_processinnate immune response
DD0045335cellular_componentphagocytic vesicle
DD0050829biological_processdefense response to Gram-negative bacterium
DD0050830biological_processdefense response to Gram-positive bacterium
DD0055085biological_processtransmembrane transport
DD0061474cellular_componentphagolysosome membrane
DD0140367biological_processantibacterial innate immune response
E0002250biological_processadaptive immune response
E0002376biological_processimmune system process
E0002468biological_processdendritic cell antigen processing and presentation
E0002478biological_processantigen processing and presentation of exogenous peptide antigen
E0005576cellular_componentextracellular region
E0022829molecular_functionwide pore channel activity
E0030659cellular_componentcytoplasmic vesicle membrane
E0030670cellular_componentphagocytic vesicle membrane
E0031410cellular_componentcytoplasmic vesicle
E0042590biological_processantigen processing and presentation of exogenous peptide antigen via MHC class I
E0042742biological_processdefense response to bacterium
E0045087biological_processinnate immune response
E0045335cellular_componentphagocytic vesicle
E0050829biological_processdefense response to Gram-negative bacterium
E0050830biological_processdefense response to Gram-positive bacterium
E0055085biological_processtransmembrane transport
E0061474cellular_componentphagolysosome membrane
E0140367biological_processantibacterial innate immune response
EE0002250biological_processadaptive immune response
EE0002376biological_processimmune system process
EE0002468biological_processdendritic cell antigen processing and presentation
EE0002478biological_processantigen processing and presentation of exogenous peptide antigen
EE0005576cellular_componentextracellular region
EE0022829molecular_functionwide pore channel activity
EE0030659cellular_componentcytoplasmic vesicle membrane
EE0030670cellular_componentphagocytic vesicle membrane
EE0031410cellular_componentcytoplasmic vesicle
EE0042590biological_processantigen processing and presentation of exogenous peptide antigen via MHC class I
EE0042742biological_processdefense response to bacterium
EE0045087biological_processinnate immune response
EE0045335cellular_componentphagocytic vesicle
EE0050829biological_processdefense response to Gram-negative bacterium
EE0050830biological_processdefense response to Gram-positive bacterium
EE0055085biological_processtransmembrane transport
EE0061474cellular_componentphagolysosome membrane
EE0140367biological_processantibacterial innate immune response
F0002250biological_processadaptive immune response
F0002376biological_processimmune system process
F0002468biological_processdendritic cell antigen processing and presentation
F0002478biological_processantigen processing and presentation of exogenous peptide antigen
F0005576cellular_componentextracellular region
F0022829molecular_functionwide pore channel activity
F0030659cellular_componentcytoplasmic vesicle membrane
F0030670cellular_componentphagocytic vesicle membrane
F0031410cellular_componentcytoplasmic vesicle
F0042590biological_processantigen processing and presentation of exogenous peptide antigen via MHC class I
F0042742biological_processdefense response to bacterium
F0045087biological_processinnate immune response
F0045335cellular_componentphagocytic vesicle
F0050829biological_processdefense response to Gram-negative bacterium
F0050830biological_processdefense response to Gram-positive bacterium
F0055085biological_processtransmembrane transport
F0061474cellular_componentphagolysosome membrane
F0140367biological_processantibacterial innate immune response
FF0002250biological_processadaptive immune response
FF0002376biological_processimmune system process
FF0002468biological_processdendritic cell antigen processing and presentation
FF0002478biological_processantigen processing and presentation of exogenous peptide antigen
FF0005576cellular_componentextracellular region
FF0022829molecular_functionwide pore channel activity
FF0030659cellular_componentcytoplasmic vesicle membrane
FF0030670cellular_componentphagocytic vesicle membrane
FF0031410cellular_componentcytoplasmic vesicle
FF0042590biological_processantigen processing and presentation of exogenous peptide antigen via MHC class I
FF0042742biological_processdefense response to bacterium
FF0045087biological_processinnate immune response
FF0045335cellular_componentphagocytic vesicle
FF0050829biological_processdefense response to Gram-negative bacterium
FF0050830biological_processdefense response to Gram-positive bacterium
FF0055085biological_processtransmembrane transport
FF0061474cellular_componentphagolysosome membrane
FF0140367biological_processantibacterial innate immune response
G0002250biological_processadaptive immune response
G0002376biological_processimmune system process
G0002468biological_processdendritic cell antigen processing and presentation
G0002478biological_processantigen processing and presentation of exogenous peptide antigen
G0005576cellular_componentextracellular region
G0022829molecular_functionwide pore channel activity
G0030659cellular_componentcytoplasmic vesicle membrane
G0030670cellular_componentphagocytic vesicle membrane
G0031410cellular_componentcytoplasmic vesicle
G0042590biological_processantigen processing and presentation of exogenous peptide antigen via MHC class I
G0042742biological_processdefense response to bacterium
G0045087biological_processinnate immune response
G0045335cellular_componentphagocytic vesicle
G0050829biological_processdefense response to Gram-negative bacterium
G0050830biological_processdefense response to Gram-positive bacterium
G0055085biological_processtransmembrane transport
G0061474cellular_componentphagolysosome membrane
G0140367biological_processantibacterial innate immune response
GG0002250biological_processadaptive immune response
GG0002376biological_processimmune system process
GG0002468biological_processdendritic cell antigen processing and presentation
GG0002478biological_processantigen processing and presentation of exogenous peptide antigen
GG0005576cellular_componentextracellular region
GG0022829molecular_functionwide pore channel activity
GG0030659cellular_componentcytoplasmic vesicle membrane
GG0030670cellular_componentphagocytic vesicle membrane
GG0031410cellular_componentcytoplasmic vesicle
GG0042590biological_processantigen processing and presentation of exogenous peptide antigen via MHC class I
GG0042742biological_processdefense response to bacterium
GG0045087biological_processinnate immune response
GG0045335cellular_componentphagocytic vesicle
GG0050829biological_processdefense response to Gram-negative bacterium
GG0050830biological_processdefense response to Gram-positive bacterium
GG0055085biological_processtransmembrane transport
GG0061474cellular_componentphagolysosome membrane
GG0140367biological_processantibacterial innate immune response
H0002250biological_processadaptive immune response
H0002376biological_processimmune system process
H0002468biological_processdendritic cell antigen processing and presentation
H0002478biological_processantigen processing and presentation of exogenous peptide antigen
H0005576cellular_componentextracellular region
H0022829molecular_functionwide pore channel activity
H0030659cellular_componentcytoplasmic vesicle membrane
H0030670cellular_componentphagocytic vesicle membrane
H0031410cellular_componentcytoplasmic vesicle
H0042590biological_processantigen processing and presentation of exogenous peptide antigen via MHC class I
H0042742biological_processdefense response to bacterium
H0045087biological_processinnate immune response
H0045335cellular_componentphagocytic vesicle
H0050829biological_processdefense response to Gram-negative bacterium
H0050830biological_processdefense response to Gram-positive bacterium
H0055085biological_processtransmembrane transport
H0061474cellular_componentphagolysosome membrane
H0140367biological_processantibacterial innate immune response
HH0002250biological_processadaptive immune response
HH0002376biological_processimmune system process
HH0002468biological_processdendritic cell antigen processing and presentation
HH0002478biological_processantigen processing and presentation of exogenous peptide antigen
HH0005576cellular_componentextracellular region
HH0022829molecular_functionwide pore channel activity
HH0030659cellular_componentcytoplasmic vesicle membrane
HH0030670cellular_componentphagocytic vesicle membrane
HH0031410cellular_componentcytoplasmic vesicle
HH0042590biological_processantigen processing and presentation of exogenous peptide antigen via MHC class I
HH0042742biological_processdefense response to bacterium
HH0045087biological_processinnate immune response
HH0045335cellular_componentphagocytic vesicle
HH0050829biological_processdefense response to Gram-negative bacterium
HH0050830biological_processdefense response to Gram-positive bacterium
HH0055085biological_processtransmembrane transport
HH0061474cellular_componentphagolysosome membrane
HH0140367biological_processantibacterial innate immune response
I0002250biological_processadaptive immune response
I0002376biological_processimmune system process
I0002468biological_processdendritic cell antigen processing and presentation
I0002478biological_processantigen processing and presentation of exogenous peptide antigen
I0005576cellular_componentextracellular region
I0022829molecular_functionwide pore channel activity
I0030659cellular_componentcytoplasmic vesicle membrane
I0030670cellular_componentphagocytic vesicle membrane
I0031410cellular_componentcytoplasmic vesicle
I0042590biological_processantigen processing and presentation of exogenous peptide antigen via MHC class I
I0042742biological_processdefense response to bacterium
I0045087biological_processinnate immune response
I0045335cellular_componentphagocytic vesicle
I0050829biological_processdefense response to Gram-negative bacterium
I0050830biological_processdefense response to Gram-positive bacterium
I0055085biological_processtransmembrane transport
I0061474cellular_componentphagolysosome membrane
I0140367biological_processantibacterial innate immune response
II0002250biological_processadaptive immune response
II0002376biological_processimmune system process
II0002468biological_processdendritic cell antigen processing and presentation
II0002478biological_processantigen processing and presentation of exogenous peptide antigen
II0005576cellular_componentextracellular region
II0022829molecular_functionwide pore channel activity
II0030659cellular_componentcytoplasmic vesicle membrane
II0030670cellular_componentphagocytic vesicle membrane
II0031410cellular_componentcytoplasmic vesicle
II0042590biological_processantigen processing and presentation of exogenous peptide antigen via MHC class I
II0042742biological_processdefense response to bacterium
II0045087biological_processinnate immune response
II0045335cellular_componentphagocytic vesicle
II0050829biological_processdefense response to Gram-negative bacterium
II0050830biological_processdefense response to Gram-positive bacterium
II0055085biological_processtransmembrane transport
II0061474cellular_componentphagolysosome membrane
II0140367biological_processantibacterial innate immune response
J0002250biological_processadaptive immune response
J0002376biological_processimmune system process
J0002468biological_processdendritic cell antigen processing and presentation
J0002478biological_processantigen processing and presentation of exogenous peptide antigen
J0005576cellular_componentextracellular region
J0022829molecular_functionwide pore channel activity
J0030659cellular_componentcytoplasmic vesicle membrane
J0030670cellular_componentphagocytic vesicle membrane
J0031410cellular_componentcytoplasmic vesicle
J0042590biological_processantigen processing and presentation of exogenous peptide antigen via MHC class I
J0042742biological_processdefense response to bacterium
J0045087biological_processinnate immune response
J0045335cellular_componentphagocytic vesicle
J0050829biological_processdefense response to Gram-negative bacterium
J0050830biological_processdefense response to Gram-positive bacterium
J0055085biological_processtransmembrane transport
J0061474cellular_componentphagolysosome membrane
J0140367biological_processantibacterial innate immune response
JJ0002250biological_processadaptive immune response
JJ0002376biological_processimmune system process
JJ0002468biological_processdendritic cell antigen processing and presentation
JJ0002478biological_processantigen processing and presentation of exogenous peptide antigen
JJ0005576cellular_componentextracellular region
JJ0022829molecular_functionwide pore channel activity
JJ0030659cellular_componentcytoplasmic vesicle membrane
JJ0030670cellular_componentphagocytic vesicle membrane
JJ0031410cellular_componentcytoplasmic vesicle
JJ0042590biological_processantigen processing and presentation of exogenous peptide antigen via MHC class I
JJ0042742biological_processdefense response to bacterium
JJ0045087biological_processinnate immune response
JJ0045335cellular_componentphagocytic vesicle
JJ0050829biological_processdefense response to Gram-negative bacterium
JJ0050830biological_processdefense response to Gram-positive bacterium
JJ0055085biological_processtransmembrane transport
JJ0061474cellular_componentphagolysosome membrane
JJ0140367biological_processantibacterial innate immune response
K0002250biological_processadaptive immune response
K0002376biological_processimmune system process
K0002468biological_processdendritic cell antigen processing and presentation
K0002478biological_processantigen processing and presentation of exogenous peptide antigen
K0005576cellular_componentextracellular region
K0022829molecular_functionwide pore channel activity
K0030659cellular_componentcytoplasmic vesicle membrane
K0030670cellular_componentphagocytic vesicle membrane
K0031410cellular_componentcytoplasmic vesicle
K0042590biological_processantigen processing and presentation of exogenous peptide antigen via MHC class I
K0042742biological_processdefense response to bacterium
K0045087biological_processinnate immune response
K0045335cellular_componentphagocytic vesicle
K0050829biological_processdefense response to Gram-negative bacterium
K0050830biological_processdefense response to Gram-positive bacterium
K0055085biological_processtransmembrane transport
K0061474cellular_componentphagolysosome membrane
K0140367biological_processantibacterial innate immune response
KK0002250biological_processadaptive immune response
KK0002376biological_processimmune system process
KK0002468biological_processdendritic cell antigen processing and presentation
KK0002478biological_processantigen processing and presentation of exogenous peptide antigen
KK0005576cellular_componentextracellular region
KK0022829molecular_functionwide pore channel activity
KK0030659cellular_componentcytoplasmic vesicle membrane
KK0030670cellular_componentphagocytic vesicle membrane
KK0031410cellular_componentcytoplasmic vesicle
KK0042590biological_processantigen processing and presentation of exogenous peptide antigen via MHC class I
KK0042742biological_processdefense response to bacterium
KK0045087biological_processinnate immune response
KK0045335cellular_componentphagocytic vesicle
KK0050829biological_processdefense response to Gram-negative bacterium
KK0050830biological_processdefense response to Gram-positive bacterium
KK0055085biological_processtransmembrane transport
KK0061474cellular_componentphagolysosome membrane
KK0140367biological_processantibacterial innate immune response
L0002250biological_processadaptive immune response
L0002376biological_processimmune system process
L0002468biological_processdendritic cell antigen processing and presentation
L0002478biological_processantigen processing and presentation of exogenous peptide antigen
L0005576cellular_componentextracellular region
L0022829molecular_functionwide pore channel activity
L0030659cellular_componentcytoplasmic vesicle membrane
L0030670cellular_componentphagocytic vesicle membrane
L0031410cellular_componentcytoplasmic vesicle
L0042590biological_processantigen processing and presentation of exogenous peptide antigen via MHC class I
L0042742biological_processdefense response to bacterium
L0045087biological_processinnate immune response
L0045335cellular_componentphagocytic vesicle
L0050829biological_processdefense response to Gram-negative bacterium
L0050830biological_processdefense response to Gram-positive bacterium
L0055085biological_processtransmembrane transport
L0061474cellular_componentphagolysosome membrane
L0140367biological_processantibacterial innate immune response
LL0002250biological_processadaptive immune response
LL0002376biological_processimmune system process
LL0002468biological_processdendritic cell antigen processing and presentation
LL0002478biological_processantigen processing and presentation of exogenous peptide antigen
LL0005576cellular_componentextracellular region
LL0022829molecular_functionwide pore channel activity
LL0030659cellular_componentcytoplasmic vesicle membrane
LL0030670cellular_componentphagocytic vesicle membrane
LL0031410cellular_componentcytoplasmic vesicle
LL0042590biological_processantigen processing and presentation of exogenous peptide antigen via MHC class I
LL0042742biological_processdefense response to bacterium
LL0045087biological_processinnate immune response
LL0045335cellular_componentphagocytic vesicle
LL0050829biological_processdefense response to Gram-negative bacterium
LL0050830biological_processdefense response to Gram-positive bacterium
LL0055085biological_processtransmembrane transport
LL0061474cellular_componentphagolysosome membrane
LL0140367biological_processantibacterial innate immune response
M0002250biological_processadaptive immune response
M0002376biological_processimmune system process
M0002468biological_processdendritic cell antigen processing and presentation
M0002478biological_processantigen processing and presentation of exogenous peptide antigen
M0005576cellular_componentextracellular region
M0022829molecular_functionwide pore channel activity
M0030659cellular_componentcytoplasmic vesicle membrane
M0030670cellular_componentphagocytic vesicle membrane
M0031410cellular_componentcytoplasmic vesicle
M0042590biological_processantigen processing and presentation of exogenous peptide antigen via MHC class I
M0042742biological_processdefense response to bacterium
M0045087biological_processinnate immune response
M0045335cellular_componentphagocytic vesicle
M0050829biological_processdefense response to Gram-negative bacterium
M0050830biological_processdefense response to Gram-positive bacterium
M0055085biological_processtransmembrane transport
M0061474cellular_componentphagolysosome membrane
M0140367biological_processantibacterial innate immune response
MM0002250biological_processadaptive immune response
MM0002376biological_processimmune system process
MM0002468biological_processdendritic cell antigen processing and presentation
MM0002478biological_processantigen processing and presentation of exogenous peptide antigen
MM0005576cellular_componentextracellular region
MM0022829molecular_functionwide pore channel activity
MM0030659cellular_componentcytoplasmic vesicle membrane
MM0030670cellular_componentphagocytic vesicle membrane
MM0031410cellular_componentcytoplasmic vesicle
MM0042590biological_processantigen processing and presentation of exogenous peptide antigen via MHC class I
MM0042742biological_processdefense response to bacterium
MM0045087biological_processinnate immune response
MM0045335cellular_componentphagocytic vesicle
MM0050829biological_processdefense response to Gram-negative bacterium
MM0050830biological_processdefense response to Gram-positive bacterium
MM0055085biological_processtransmembrane transport
MM0061474cellular_componentphagolysosome membrane
MM0140367biological_processantibacterial innate immune response
N0002250biological_processadaptive immune response
N0002376biological_processimmune system process
N0002468biological_processdendritic cell antigen processing and presentation
N0002478biological_processantigen processing and presentation of exogenous peptide antigen
N0005576cellular_componentextracellular region
N0022829molecular_functionwide pore channel activity
N0030659cellular_componentcytoplasmic vesicle membrane
N0030670cellular_componentphagocytic vesicle membrane
N0031410cellular_componentcytoplasmic vesicle
N0042590biological_processantigen processing and presentation of exogenous peptide antigen via MHC class I
N0042742biological_processdefense response to bacterium
N0045087biological_processinnate immune response
N0045335cellular_componentphagocytic vesicle
N0050829biological_processdefense response to Gram-negative bacterium
N0050830biological_processdefense response to Gram-positive bacterium
N0055085biological_processtransmembrane transport
N0061474cellular_componentphagolysosome membrane
N0140367biological_processantibacterial innate immune response
NN0002250biological_processadaptive immune response
NN0002376biological_processimmune system process
NN0002468biological_processdendritic cell antigen processing and presentation
NN0002478biological_processantigen processing and presentation of exogenous peptide antigen
NN0005576cellular_componentextracellular region
NN0022829molecular_functionwide pore channel activity
NN0030659cellular_componentcytoplasmic vesicle membrane
NN0030670cellular_componentphagocytic vesicle membrane
NN0031410cellular_componentcytoplasmic vesicle
NN0042590biological_processantigen processing and presentation of exogenous peptide antigen via MHC class I
NN0042742biological_processdefense response to bacterium
NN0045087biological_processinnate immune response
NN0045335cellular_componentphagocytic vesicle
NN0050829biological_processdefense response to Gram-negative bacterium
NN0050830biological_processdefense response to Gram-positive bacterium
NN0055085biological_processtransmembrane transport
NN0061474cellular_componentphagolysosome membrane
NN0140367biological_processantibacterial innate immune response
O0002250biological_processadaptive immune response
O0002376biological_processimmune system process
O0002468biological_processdendritic cell antigen processing and presentation
O0002478biological_processantigen processing and presentation of exogenous peptide antigen
O0005576cellular_componentextracellular region
O0022829molecular_functionwide pore channel activity
O0030659cellular_componentcytoplasmic vesicle membrane
O0030670cellular_componentphagocytic vesicle membrane
O0031410cellular_componentcytoplasmic vesicle
O0042590biological_processantigen processing and presentation of exogenous peptide antigen via MHC class I
O0042742biological_processdefense response to bacterium
O0045087biological_processinnate immune response
O0045335cellular_componentphagocytic vesicle
O0050829biological_processdefense response to Gram-negative bacterium
O0050830biological_processdefense response to Gram-positive bacterium
O0055085biological_processtransmembrane transport
O0061474cellular_componentphagolysosome membrane
O0140367biological_processantibacterial innate immune response
OO0002250biological_processadaptive immune response
OO0002376biological_processimmune system process
OO0002468biological_processdendritic cell antigen processing and presentation
OO0002478biological_processantigen processing and presentation of exogenous peptide antigen
OO0005576cellular_componentextracellular region
OO0022829molecular_functionwide pore channel activity
OO0030659cellular_componentcytoplasmic vesicle membrane
OO0030670cellular_componentphagocytic vesicle membrane
OO0031410cellular_componentcytoplasmic vesicle
OO0042590biological_processantigen processing and presentation of exogenous peptide antigen via MHC class I
OO0042742biological_processdefense response to bacterium
OO0045087biological_processinnate immune response
OO0045335cellular_componentphagocytic vesicle
OO0050829biological_processdefense response to Gram-negative bacterium
OO0050830biological_processdefense response to Gram-positive bacterium
OO0055085biological_processtransmembrane transport
OO0061474cellular_componentphagolysosome membrane
OO0140367biological_processantibacterial innate immune response
P0002250biological_processadaptive immune response
P0002376biological_processimmune system process
P0002468biological_processdendritic cell antigen processing and presentation
P0002478biological_processantigen processing and presentation of exogenous peptide antigen
P0005576cellular_componentextracellular region
P0022829molecular_functionwide pore channel activity
P0030659cellular_componentcytoplasmic vesicle membrane
P0030670cellular_componentphagocytic vesicle membrane
P0031410cellular_componentcytoplasmic vesicle
P0042590biological_processantigen processing and presentation of exogenous peptide antigen via MHC class I
P0042742biological_processdefense response to bacterium
P0045087biological_processinnate immune response
P0045335cellular_componentphagocytic vesicle
P0050829biological_processdefense response to Gram-negative bacterium
P0050830biological_processdefense response to Gram-positive bacterium
P0055085biological_processtransmembrane transport
P0061474cellular_componentphagolysosome membrane
P0140367biological_processantibacterial innate immune response
PP0002250biological_processadaptive immune response
PP0002376biological_processimmune system process
PP0002468biological_processdendritic cell antigen processing and presentation
PP0002478biological_processantigen processing and presentation of exogenous peptide antigen
PP0005576cellular_componentextracellular region
PP0022829molecular_functionwide pore channel activity
PP0030659cellular_componentcytoplasmic vesicle membrane
PP0030670cellular_componentphagocytic vesicle membrane
PP0031410cellular_componentcytoplasmic vesicle
PP0042590biological_processantigen processing and presentation of exogenous peptide antigen via MHC class I
PP0042742biological_processdefense response to bacterium
PP0045087biological_processinnate immune response
PP0045335cellular_componentphagocytic vesicle
PP0050829biological_processdefense response to Gram-negative bacterium
PP0050830biological_processdefense response to Gram-positive bacterium
PP0055085biological_processtransmembrane transport
PP0061474cellular_componentphagolysosome membrane
PP0140367biological_processantibacterial innate immune response
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues928
DetailsTransmembrane: {"description":"Beta stranded","evidences":[{"source":"UniProtKB","id":"A1L314","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues10080
DetailsDomain: {"description":"MACPF","evidences":[{"source":"PROSITE-ProRule","id":"PRU00745","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues96
DetailsSite: {"description":"Cleavage; by LGMN","evidences":[{"source":"UniProtKB","id":"A1L314","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI4
Number of Residues32
DetailsSite: {"description":"Cleavage; by trypsin","evidences":[{"source":"UniProtKB","id":"A1L314","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI5
Number of Residues64
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"31537793","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6U23","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6U2J","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6U2K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6U2L","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6U2W","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

site_idSWS_FT_FI6
Number of Residues32
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

243911

PDB entries from 2025-10-29

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