6TEO
Crystal structure of a yeast Snu114-Prp8 complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000244 | biological_process | spliceosomal tri-snRNP complex assembly |
| A | 0000349 | biological_process | generation of catalytic spliceosome for first transesterification step |
| A | 0000387 | biological_process | spliceosomal snRNP assembly |
| A | 0000388 | biological_process | spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) |
| A | 0000398 | biological_process | mRNA splicing, via spliceosome |
| A | 0000974 | cellular_component | Prp19 complex |
| A | 0003924 | molecular_function | GTPase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005525 | molecular_function | GTP binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005682 | cellular_component | U5 snRNP |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006397 | biological_process | mRNA processing |
| A | 0008380 | biological_process | RNA splicing |
| A | 0030623 | molecular_function | U5 snRNA binding |
| A | 0046540 | cellular_component | U4/U6 x U5 tri-snRNP complex |
| A | 0071007 | cellular_component | U2-type catalytic step 2 spliceosome |
| B | 0000398 | biological_process | mRNA splicing, via spliceosome |
| B | 0005681 | cellular_component | spliceosomal complex |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0000244 | biological_process | spliceosomal tri-snRNP complex assembly |
| C | 0000349 | biological_process | generation of catalytic spliceosome for first transesterification step |
| C | 0000387 | biological_process | spliceosomal snRNP assembly |
| C | 0000388 | biological_process | spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) |
| C | 0000398 | biological_process | mRNA splicing, via spliceosome |
| C | 0000974 | cellular_component | Prp19 complex |
| C | 0003924 | molecular_function | GTPase activity |
| C | 0005515 | molecular_function | protein binding |
| C | 0005525 | molecular_function | GTP binding |
| C | 0005634 | cellular_component | nucleus |
| C | 0005682 | cellular_component | U5 snRNP |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0006397 | biological_process | mRNA processing |
| C | 0008380 | biological_process | RNA splicing |
| C | 0030623 | molecular_function | U5 snRNA binding |
| C | 0046540 | cellular_component | U4/U6 x U5 tri-snRNP complex |
| C | 0071007 | cellular_component | U2-type catalytic step 2 spliceosome |
| D | 0000398 | biological_process | mRNA splicing, via spliceosome |
| D | 0005681 | cellular_component | spliceosomal complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 1101 |
| Chain | Residue |
| A | GLN251 |
| A | LYS254 |
| A | HIS934 |
| site_id | AC2 |
| Number of Residues | 20 |
| Details | binding site for residue GTP A 1102 |
| Chain | Residue |
| A | THR147 |
| A | SER148 |
| A | LEU189 |
| A | SER190 |
| A | PRO216 |
| A | GLY217 |
| A | ASN268 |
| A | LYS269 |
| A | ASP271 |
| A | SER315 |
| A | THR316 |
| A | LYS317 |
| A | MG1103 |
| A | HOH1201 |
| A | PRO141 |
| A | LEU142 |
| A | HIS143 |
| A | SER144 |
| A | GLY145 |
| A | LYS146 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 1103 |
| Chain | Residue |
| A | THR147 |
| A | ASP179 |
| A | LEU189 |
| A | SER190 |
| A | GTP1102 |
| A | HOH1201 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 C 1101 |
| Chain | Residue |
| C | GLN251 |
| C | LYS254 |
| C | ARG725 |
| C | HIS934 |
| site_id | AC5 |
| Number of Residues | 19 |
| Details | binding site for residue GTP C 1102 |
| Chain | Residue |
| C | PRO141 |
| C | LEU142 |
| C | HIS143 |
| C | SER144 |
| C | GLY145 |
| C | LYS146 |
| C | THR147 |
| C | SER148 |
| C | LEU189 |
| C | SER190 |
| C | GLY217 |
| C | ASN268 |
| C | LYS269 |
| C | ASP271 |
| C | SER315 |
| C | THR316 |
| C | LYS317 |
| C | MG1103 |
| C | HOH1202 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue MG C 1103 |
| Chain | Residue |
| C | THR147 |
| C | SER190 |
| C | GTP1102 |
| C | HOH1202 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 414 |
| Details | Domain: {"description":"tr-type G","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 14 |
| Details | Region: {"description":"G1","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Region: {"description":"G2","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Region: {"description":"G3","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | Region: {"description":"G4","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | Region: {"description":"G5","evidences":[{"source":"PROSITE-ProRule","id":"PRU01059","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 28 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
