6TDC

PPAR gamma ligand binding domain in complex with MRL-871

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0004879	molecular_function	nuclear receptor activity
A	0005634	cellular_component	nucleus
A	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PDB Data

site_id	AC1
Number of Residues	15
Details	binding site for residue 4F1 A 601

Chain	Residue
A	PHE310
A	SER370
A	PHE391
A	MET392
A	LYS395
A	PHE396
A	HIS477
A	CYS313
A	GLN314
A	ARG316
A	SER317
A	ILE354
A	LEU358
A	MET362
A	ILE369

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site_id	AC2
Number of Residues	4
Details	binding site for residue GOL A 602

Chain	Residue
A	ARG240
A	THR266
A	LYS268
A	GLN448

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG

Chain	Residue	Details
A	GLN342
A	GLU379
A	TYR505

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site_id	SWS_FT_FI2
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:36737649

Chain	Residue	Details
A	MET280

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